FZR3_ARATH - dbPTM
FZR3_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID FZR3_ARATH
UniProt AC Q8LPL5
Protein Name Protein FIZZY-RELATED 3
Gene Name FZR3
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 481
Subcellular Localization
Protein Description Activator protein that regulates the ubiquitin ligase activity and substrate specificity of the anaphase promoting complex/cyclosome (APC/C)..
Protein Sequence MASPQSTKTGLNLPAGMNQTSLRLETFSSSFRGISSLSSPSKSTCSDRFIPCRSSSRLHAFDLQDKEPTTPVKEGGNEAYSRLLKSELFGSDFASPLLSPAGGQGSASSPMSPCTNMLRFKTDRSNSSPSSPFSPSILGNDNGHSSDSSPPPKPPRKVPKTPHKVLDAPSLQDDFYLNVVDWSSQNVLAVGLGTCVYLWTASNSKVTKLCDLGPNDSVCSVQWTREGSYISIGTSHGQVQVWDGTQCKRVRTMGGHQTRTGVLAWNSRILSSGSRDRNILQHDIRVQSDFVSKLVGHKSEVCGLKWSHDDRELASGGNDNQLLVWNNHSQQPILKLTEHTAAVKAITWSPHQSSLLASGGGTADRCIRFWNTTNGNQLNSIDTGSQVCNLAWSKNVNEIVSTHGYSQNQIMLWKYPSMSKVATLTGHSMRVLYLATSPDGQTIVTGAGDETLRFWNVFPSVKMQTPVKDTGLWSLGRTQIR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
460PhosphorylationRFWNVFPSVKMQTPV
EEEECCCCCCCCCCC
23.9328295753
465PhosphorylationFPSVKMQTPVKDTGL
CCCCCCCCCCCCCCC
26.9328295753

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of FZR3_ARATH !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of FZR3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of FZR3_ARATH !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
APC4_SCHPOcut20physical
15970679
CDKA1_ARATHCDC2physical
15970679
CCB23_ARATHCYCB2;3physical
20407024
APC2_ARATHAPC2physical
20706207
CDC23_ARATHAPC8physical
20706207
CKS2_ARATHCKS2physical
20706207
PYM_ARATHUVI4physical
20706207
GIG1_ARATHUVI4-LIKEphysical
20706207
CD27B_ARATHHBTphysical
20706207
APC1_ARATHEMB2771physical
20706207
APC4_ARATHAT4G21530physical
20706207
APC5_ARATHAT1G06590physical
20706207
APC7_ARATHAT2G39090physical
20706207
CDC16_ARATHAPC6physical
20706207
CKS1_ARATHCKS1physical
20706207
SKIP_ARATHSKIPphysical
20706207
IF2B_ARATHEIF2 BETAphysical
20706207
PGMC1_ARATHAT1G23190physical
20706207
THO4B_ARATHAT5G02530physical
20706207
TCPA_ARATHTCP-1physical
20706207

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of FZR3_ARATH

loading...

Related Literatures of Post-Translational Modification

TOP