PGMC1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PGMC1_ARATH
• UniProt AC: O49299
• Protein Name: Probable phosphoglucomutase, cytoplasmic 1
• Gene Name: At1g23190
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 583
• Subcellular Localization: Cytoplasm.
• Protein Description: This enzyme participates in both the breakdown and synthesis of glucose..
• Protein Sequence: MVFKVSTVSTSPIDGQKPGTSGLRKKVKVFKQPNYLENFVQATFNALTAEKVKGATLVVSGDGRYYSKDAVQIIIKMAAANGVRRVWVGKNTLLSTPAVSAVIRERSGADGSKATGAFILTASHNPGGPTEDFGIKYNMENGGPAPESITDKIYENTKTIKEYPIAQDLPNVDISAVGVTSFEGPEGKFDVEVFDPADDYVKLMKSIFDFEAIRKLLSSPKFTFCYDALHGVAGAYAHRIFVEELGAQESALLNCTPKEDFGGGHPDPNLTYAKELVARMGLGKSDTGGEPPEFGAAADGDADRNMILGKRFFVTPSDSVAIIAANAIGAIPYFSSGLKGVARSMPTSAALDVVAKSLNLKFFEVPTGWKFFGNLMDAGMCSVCGEESFGTGSDHIREKDGIWAVLAWMSILAHKNKGNIDGNAKLVSVEDIVRQHWATYGRHYYTRYDYENVDAGKAKELMEHLVKLQSSIPEVNKIVKGIRSDVASVASADEFEYKDPVDGSISKHQGIRYLFEDGSRLVFRLSGTGSEGATIRLYIEQYEKDASKTGRESQEALSPLVDLALKLSKMEEFTGRSAPTVIT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	VFKVSTVSTSPIDGQ CEEEEEEECCCCCCC	24.21	29654922
21	Phosphorylation	DGQKPGTSGLRKKVK CCCCCCCCCHHHHCE	41.57	29654922
56	Phosphorylation	AEKVKGATLVVSGDG HHHCCCCEEEECCCC	28.84	28295753
66	Phosphorylation	VSGDGRYYSKDAVQI ECCCCCEECHHHHHH	14.10	28295753
67	Phosphorylation	SGDGRYYSKDAVQII CCCCCEECHHHHHHH	18.35	28295753
115	Phosphorylation	GADGSKATGAFILTA CCCCCCCCEEEEEEE	32.55	23776212
121	Phosphorylation	ATGAFILTASHNPGG CCEEEEEEECCCCCC	22.69	24601666
123	Phosphorylation	GAFILTASHNPGGPT EEEEEEECCCCCCCH	20.68	30291188
130	Phosphorylation	SHNPGGPTEDFGIKY CCCCCCCHHHCCCEE	52.00	23776212
280	Sulfoxidation	AKELVARMGLGKSDT HHHHHHHHCCCCCCC	3.61	25693801
287	Phosphorylation	MGLGKSDTGGEPPEF HCCCCCCCCCCCCCC	54.93	19880383
317	Phosphorylation	KRFFVTPSDSVAIIA CEEEECCCHHHHHHH	32.90	23111157
336	Phosphorylation	GAIPYFSSGLKGVAR CHHHCCCCCHHHHHH	37.94	23111157
345	Sulfoxidation	LKGVARSMPTSAALD HHHHHHHCCCHHHHH	3.32	25693801
484	Phosphorylation	KIVKGIRSDVASVAS HHHHHHHHCHHHHCC	34.22	23776212
488	Phosphorylation	GIRSDVASVASADEF HHHHCHHHHCCCCCC	20.33	30291188
491	Phosphorylation	SDVASVASADEFEYK HCHHHHCCCCCCCCC	33.81	23776212
497	Phosphorylation	ASADEFEYKDPVDGS CCCCCCCCCCCCCCC	26.47	23776212
526	Phosphorylation	SRLVFRLSGTGSEGA CEEEEEEECCCCCCE	30.01	25561503
530	Phosphorylation	FRLSGTGSEGATIRL EEEECCCCCCEEEEE	32.47	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PGMC1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PGMC1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PGMC1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SUMO3_ARATH	SUMO3	physical	20855607
SUMO1_ARATH	SUMO1	physical	20855607

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.