| UniProt ID | SKIP_ARATH | |
|---|---|---|
| UniProt AC | O80653 | |
| Protein Name | SNW/SKI-interacting protein | |
| Gene Name | SKIP | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 613 | |
| Subcellular Localization | Nucleus speckle . | |
| Protein Description | Splicing factor involved in post-transcriptional regulation of circadian clock and flowering time genes. Associates with the pre-mRNA of PRR7, PRR9, ELF3 and GI, and is necessary for the regulation of their alternative splicing and mRNA maturation. Probably involved in splice site recognition.. | |
| Protein Sequence | MKSLNDLPAPKSTTTTYYDHSNDAWFKNRVTESETVKSSSIKFKVVPAYLNRQGLRPKNPEDFGDGGAFPEIHLPQYPLLMGKNKSNKPGAKTLPVTVDAQGNVVFDAIVRQNENSRKIVYSQHKDIIPKFLKNEGDLGTVVDEEEELQKEIQETAEETKAAIEKIVNVRLSAAQPSNIARQSGDSQYIKYKPSQQSSAFNSGAKERIIRMVEMPVDPLDPPKFKHKRVPRASGSPPVPVMHSPPRPVTVKDQQDWKIPPCISNWKNPKGYTIPLDKRLAADGRGLQDVQINDNFAKLSEALYVAEQKAREAVSMRSKVQKEMVMKDKERKEQELRALAQKARSERTGAAMSMPVSSDRGRSESVDPRGDYDNYDQDRGREREREEPQETREEREKRIQREKIREERRRERERERRLDAKDAAMGKKSKITRDRDRDISEKVALGMASTGGKGGGEVMYDQRLFNQDKGMDSGFAADDQYNLYDKGLFTAQPTLSTLYKPKKDNDEEMYGNADEQLDKIKNTERFKPDKAFTGASERVGSKRDRPVEFEKEEEQDPFGLEKWVSDLKKGKKPLDKIGSGGTMRASGGGGSSSRDDDHGGSGRTKINFERSDRR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 33 | Phosphorylation | FKNRVTESETVKSSS HHCCCCCCCEECCCC | 23111157 | ||
| 35 | Phosphorylation | NRVTESETVKSSSIK CCCCCCCEECCCCCE | 24894044 | ||
| 39 | Phosphorylation | ESETVKSSSIKFKVV CCCEECCCCCEEEEE | 23111157 | ||
| 172 | Phosphorylation | KIVNVRLSAAQPSNI HHHHCCCCCCCCCHH | 24243849 | ||
| 177 | Phosphorylation | RLSAAQPSNIARQSG CCCCCCCCHHHCCCC | 19880383 | ||
| 233 | Phosphorylation | HKRVPRASGSPPVPV CCCCCCCCCCCCCCC | 27532006 | ||
| 235 | Phosphorylation | RVPRASGSPPVPVMH CCCCCCCCCCCCCCC | 27532006 | ||
| 243 | Phosphorylation | PPVPVMHSPPRPVTV CCCCCCCCCCCCEEC | 27532006 | ||
| 249 | Phosphorylation | HSPPRPVTVKDQQDW CCCCCCEECCCCCCC | 23776212 | ||
| 352 | Phosphorylation | ERTGAAMSMPVSSDR HCCCCCCCCCCCCCC | 25561503 | ||
| 356 | Phosphorylation | AAMSMPVSSDRGRSE CCCCCCCCCCCCCCC | 30407730 | ||
| 357 | Phosphorylation | AMSMPVSSDRGRSES CCCCCCCCCCCCCCC | 25561503 | ||
| 362 | Phosphorylation | VSSDRGRSESVDPRG CCCCCCCCCCCCCCC | 25561503 | ||
| 364 | Phosphorylation | SDRGRSESVDPRGDY CCCCCCCCCCCCCCC | 25561503 | ||
| 449 | Phosphorylation | VALGMASTGGKGGGE HHHHCCCCCCCCCCC | 22074104 | ||
| 578 | Phosphorylation | KPLDKIGSGGTMRAS CCHHHCCCCCCEECC | 25561503 | ||
| 590 | Phosphorylation | RASGGGGSSSRDDDH ECCCCCCCCCCCCCC | 29654922 | ||
| 591 | Phosphorylation | ASGGGGSSSRDDDHG CCCCCCCCCCCCCCC | 29654922 | ||
| 592 | Phosphorylation | SGGGGSSSRDDDHGG CCCCCCCCCCCCCCC | 29654922 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SKIP_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SKIP_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SKIP_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| SR45_ARATH | SR45 | physical | 22942380 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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