CRWN4_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CRWN4_ARATH
• UniProt AC: Q9FLH0
• Protein Name: Protein CROWDED NUCLEI 4 {ECO:0000303|PubMed:24308514}
• Gene Name: CRWN4 {ECO:0000303|PubMed:24308514}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 1010
• Subcellular Localization: Nucleus membrane ; Peripheral membrane protein . Nucleus, nucleoplasm . Nucleus lamina . Cytoplasm . Recruited to the nucleus envelope (NE) by SUN proteins and is immobilised therein (By similarity). Localized frequently to the nuclear periphery as p
• Protein Description: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments (By similarity). Required for nucleus structure organization (e.g. size and shape). [PubMed: 24308514]
• Protein Sequence: MATSSRSERFPITPSTAATNRLTITPNSRVLKSPLTEEIMWKRLKDAGFDEQSIKNRDKAALIAYIAKLESEVYDYQHNMGLLLLEKNELSSQYEEIKASVDESDLTHMREKSAYVSALAEAKKREESLKKDVGIAKECISSLEKTLHEMRAECAETKVSAGSTMSEAHVMIEDALKKLADAEAKMRAAEALQAEANRYHRIAERKLKEVESREDDLTRRLASFKSECETKENEMVIERQTLNERRKSLQQEHERLLDAQVSLNQREDHIFARSQELAELEKGLDTAKTTFEEERKAFEDKKSNLEIALALCAKREEAVSERESSLLKKEQELLVAEEKIASKESELIQNVLANQEVILRKRKSDVEAELECKSKSVEVEIESKRRAWELREVDIKQREDLVGEKEHDLEVQSRALAEKEKDITEKSFNLDEKEKNLVATEEDINRKTTMLEDEKERLRKLDLELQQSLTSLEDKRKRVDSATQKLEALKSETSELSTLEMKLKEELDDLRAQKLEMLAEADRLKVEKAKFEAEWEHIDVKREELRKEAEYITRQREAFSMYLKDERDNIKEERDALRNQHKNDVESLNREREEFMNKMVEEHSEWLSKIQRERADFLLGIEMQKRELEYCIENKREELENSSRDREKAFEQEKKLEEERIQSLKEMAEKELEHVQVELKRLDAERLEIKLDRERREREWAELKDSVEELKVQREKLETQRHMLRAERDEIRHEIEELKKLENLKVALDDMSMAKMQLSNLERSWEKVSALKQKVVSRDDELDLQNGVSTVSNSEDGYNSSMERQNGLTPSSATPFSWIKRCTNLIFKTSPEKSTLMHHYEEEGGVPSEKLKLESSRREEKAYTEGLSIAVERLEAGRKRRGNTSGDETSEPSNNKKRKHDVTQKYSDEADTQSVISSPQNVPEDKHELPSSQTQTPSGMVVISETVKITRVTCETEVTNKVTTLDCSESPSEAGRKMGEETEDGDCNQTGINASETVIHNEAATEDICT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MATSSRSERF -----CCCCCCCCCC		25561503
4	Phosphorylation	----MATSSRSERFP ----CCCCCCCCCCC		25561503
5	Phosphorylation	---MATSSRSERFPI ---CCCCCCCCCCCC		25561503
7	Phosphorylation	-MATSSRSERFPITP -CCCCCCCCCCCCCC		25561503
13	Phosphorylation	RSERFPITPSTAATN CCCCCCCCCCCCCCC		25561503
15	Phosphorylation	ERFPITPSTAATNRL CCCCCCCCCCCCCCE		25561503
16	Phosphorylation	RFPITPSTAATNRLT CCCCCCCCCCCCCEE		25561503
759	Phosphorylation	SMAKMQLSNLERSWE HHHHHHHHHHHHHHH		30407730
789	Phosphorylation	LDLQNGVSTVSNSED CCCCCCCEECCCCCC		23776212
790	Phosphorylation	DLQNGVSTVSNSEDG CCCCCCEECCCCCCC		23776212
792	Phosphorylation	QNGVSTVSNSEDGYN CCCCEECCCCCCCCC		23776212
794	Phosphorylation	GVSTVSNSEDGYNSS CCEECCCCCCCCCCH		23776212
798	Phosphorylation	VSNSEDGYNSSMERQ CCCCCCCCCCHHHHC		23776212
800	Phosphorylation	NSEDGYNSSMERQNG CCCCCCCCHHHHCCC		23776212
801	Phosphorylation	SEDGYNSSMERQNGL CCCCCCCHHHHCCCC		23776212
848	Phosphorylation	EEEGGVPSEKLKLES CCCCCCCHHHHCCCH		25561503
884	Phosphorylation	GRKRRGNTSGDETSE HCCCCCCCCCCCCCC		23776212
885	Phosphorylation	RKRRGNTSGDETSEP CCCCCCCCCCCCCCC		23776212
889	Phosphorylation	GNTSGDETSEPSNNK CCCCCCCCCCCCCCC		23776212
890	Phosphorylation	NTSGDETSEPSNNKK CCCCCCCCCCCCCCC		23776212
893	Phosphorylation	GDETSEPSNNKKRKH CCCCCCCCCCCCCCC		23776212
914	Phosphorylation	SDEADTQSVISSPQN CCCHHHHHHCCCCCC		30407730
917	Phosphorylation	ADTQSVISSPQNVPE HHHHHHCCCCCCCCC		30407730
918	Phosphorylation	DTQSVISSPQNVPED HHHHHCCCCCCCCCC		30407730
968	Phosphorylation	KVTTLDCSESPSEAG CCEEEECCCCHHHHH		23776212
970	Phosphorylation	TTLDCSESPSEAGRK EEEECCCCHHHHHHH		30291188
972	Phosphorylation	LDCSESPSEAGRKMG EECCCCHHHHHHHCC		30291188
995	Phosphorylation	NQTGINASETVIHNE CCCCCCCCCEEECCC		18463617
997	Phosphorylation	TGINASETVIHNEAA CCCCCCCEEECCCHH		18463617
999	Phosphorylation	INASETVIHNEAATE CCCCCEEECCCHHCC		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CRWN4_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CRWN4_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CRWN4_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of CRWN4_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.