GCSP1_ARATH - dbPTM
GCSP1_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID GCSP1_ARATH
UniProt AC Q94B78
Protein Name Glycine dehydrogenase (decarboxylating) 1, mitochondrial
Gene Name GLDP1
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 1037
Subcellular Localization Mitochondrion .
Protein Description The glycine decarboxylase (GDC) or glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (By similarity)..
Protein Sequence MERARRLAYRGIVKRLVNDTKRHRNAETPHLVPHAPARYVSSLSPFISTPRSVNHTAAFGRHQQTRSISVDAVKPSDTFPRRHNSATPDEQTHMAKFCGFDHIDSLIDATVPKSIRLDSMKFSKFDAGLTESQMIQHMVDLASKNKVFKSFIGMGYYNTHVPTVILRNIMENPAWYTQYTPYQAEISQGRLESLLNFQTVITDLTGLPMSNASLLDEGTAAAEAMAMCNNILKGKKKTFVIASNCHPQTIDVCKTRADGFDLKVVTSDLKDIDYSSGDVCGVLVQYPGTEGEVLDYAEFVKNAHANGVKVVMATDLLALTVLKPPGEFGADIVVGSAQRFGVPMGYGGPHAAFLATSQEYKRMMPGRIIGISVDSSGKQALRMAMQTREQHIRRDKATSNICTAQALLANMAAMYAVYHGPAGLKSIAQRVHGLAGIFSLGLNKLGVAEVQELPFFDTVKIKCSDAHAIADAASKSEINLRVVDSTTITASFDETTTLDDVDKLFKVFASGKPVPFTAESLAPEVQNSIPSSLTRESPYLTHPIFNMYHTEHELLRYIHKLQSKDLSLCHSMIPLGSCTMKLNATTEMMPVTWPSFTDIHPFAPVEQAQGYQEMFENLGDLLCTITGFDSFSLQPNAGAAGEYAGLMVIRAYHMSRGDHHRNVCIIPVSAHGTNPASAAMCGMKIITVGTDAKGNINIEEVRKAAEANKDNLAALMVTYPSTHGVYEEGIDEICNIIHENGGQVYMDGANMNAQVGLTSPGFIGADVCHLNLHKTFCIPHGGGGPGMGPIGVKNHLAPFLPSHPVIPTGGIPQPEKTAPLGAISAAPWGSALILPISYTYIAMMGSGGLTDASKIAILNANYMAKRLEKHYPVLFRGVNGTVAHEFIIDLRGFKNTAGIEPEDVAKRLMDYGFHGPTMSWPVPGTLMIEPTESESKAELDRFCDALISIREEIAQIEKGNADVQNNVLKGAPHPPSLLMADTWKKPYSREYAAFPAPWLRSSKFWPTTGRVDNVYGDRKLVCTLLPEEEQVAAAVSA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
39PhosphorylationVPHAPARYVSSLSPF
CCCCCHHHHCCCCCC		27.2028295753
42PhosphorylationAPARYVSSLSPFIST
CCHHHHCCCCCCCCC		3.1428295753
48PhosphorylationSSLSPFISTPRSVNH
CCCCCCCCCCCCCCC		5.3328295753
67PhosphorylationGRHQQTRSISVDAVK
CCCCCCCEEEEEEEC		28.8028295753
69PhosphorylationHQQTRSISVDAVKPS
CCCCCEEEEEEECCH		28.9228295753
78PhosphorylationDAVKPSDTFPRRHNS
EEECCHHCCCCCCCC		7.8828295753
98GlutathionylationQTHMAKFCGFDHIDS
HHHHHHHCCCCCHHH		31.0816286078
263AcetylationRADGFDLKVVTSDLK
CCCCCCEEEEECCCC		26.8924727099
267PhosphorylationFDLKVVTSDLKDIDY
CCEEEEECCCCCCCC		51.6219880383
402GlutathionylationDKATSNICTAQALLA
HHHHHCHHHHHHHHH		52.3216286078
463GlutathionylationFDTVKIKCSDAHAIA
CEEEEEEECCHHHHH		51.4716286078
557PhosphorylationTEHELLRYIHKLQSK
CHHHHHHHHHHHCCC		23.2722440515
774OtherVCHLNLHKTFCIPHG
EEECEEECEEEECCC		2.88-
774N6-(pyridoxal phosphate)lysineVCHLNLHKTFCIPHG
EEECEEECEEEECCC		2.88-
777GlutathionylationLNLHKTFCIPHGGGG
CEEECEEEECCCCCC		19.2116286078
817PhosphorylationGIPQPEKTAPLGAIS
CCCCCCCCCCCCCCC		3.5525368622
824PhosphorylationTAPLGAISAAPWGSA
CCCCCCCCCCCCCCE		20.1625368622
830PhosphorylationISAAPWGSALILPIS
CCCCCCCCEEEEEEE		20.4425368622
837PhosphorylationSALILPISYTYIAMM
CEEEEEEEEEEEHHH		8.4925368622
838PhosphorylationALILPISYTYIAMMG
EEEEEEEEEEEHHHC		4.4125368622
839PhosphorylationLILPISYTYIAMMGS
EEEEEEEEEEHHHCC		4.2625368622
840PhosphorylationILPISYTYIAMMGSG
EEEEEEEEEHHHCCC		2.9925368622
896PhosphorylationDLRGFKNTAGIEPED
ECCCCCCCCCCCHHH		3.9829797451
943GlutathionylationKAELDRFCDALISIR
HHHHHHHHHHHHHHH		31.6816286078
958AcetylationEEIAQIEKGNADVQN
HHHHHHHCCCHHHHC		37.7824727099
1001PhosphorylationFPAPWLRSSKFWPTT
CCCHHHHCCCCCCCC		32.4625561503
1002PhosphorylationPAPWLRSSKFWPTTG
CCHHHHCCCCCCCCC		11.0525561503
1022GlutathionylationYGDRKLVCTLLPEEE
ECCCEEEEEECCHHH		24.1016286078
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of GCSP1_ARATH !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference
98CGlutathionylation

20089767
777CGlutathionylation

20089767
943CGlutathionylation

20089767
1022CGlutathionylation

20571115
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of GCSP1_ARATH !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of GCSP1_ARATH !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of GCSP1_ARATH

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Related Literatures of Post-Translational Modification

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