dbPTM

HAC5_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HAC5_ARATH
UniProt AC	Q9LE42
Protein Name	Histone acetyltransferase HAC5
Gene Name	HAC5
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	1670
Subcellular Localization	Nucleus .
Protein Description	Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation..
Protein Sequence	MAQGQNRTVLQSGQMHNSVVASASSVSSQPNMVNGISQDTLLLRQEMLNRTYAWLQQRQPSKTDDASKAKLSEVAKRLESAMWRTATSKEDYLDFRSFDVRVESTLKQLLSQRRANPSSSVSTMVQTPGVSHGWGQSYTATPMVDTSKFNSSNNLSDATTETGRLLPTNRMYRGTINNGRQELSAVGQMIPTPGFDNSANADVYQSHRNEEYSGDGGKLLATGSDFGNPSQLQKQRPTGSNDLMGYNLDHQLGGGFRSNIHQNTSGMTSIPLNAGVGMSGNNVHLANVPRSSEGVLSSTHFSTFSQPSQQPVEQLQVSHVNRYSMSNSGTFVSGNLYGVQTSSGSIETAVDMNSMSLNSMRRVDTSFGSQSGLQNNPLLKPHLRHQFENGNFQSSSNSKENLAQVSHRPLERQFNQQAHYGQYHQQELLMNNDAYRQSQPASNLVSQVKNEPRVEYYNEAFQMQAINKVEPSKPQNQYKQNTVKDEYVGAQSAPVSSSQLKMSPSFPPQTHQTQQVSQWKDSSSLSAGVQPVSGLGQWHSSSQNLTPISKNSNEEREHFGVRFHKQHEGTNNSSSVRESTNCLTVAPSGTLDVPHLPVGINVLSKQLNGDCGLSYKNQRRWLLFLLHVRKCNAAEDNCESKYCFTAKTLLKHINCCKAPACAYQYCHQTRQLIHHYKHCGDEACPVCVFVKNFKEKQKEKFTFLQRAEPSSASLNHGPKESFESMRTSSERDSEAPFVVDDLQPSPKRQKVEKPSQFAYPDTQGNPATISAGVSQAHFSMGLQEKDRLPSDVCKPVRSNVPMNADSSDSSRRLVPVSRELEKPVCKDTHMGRHGVKSALDGESLRLSKQEKPKRMNEISAPKEENAEQSLGVVSASNCGKSKIKGVSLIELFTPEQVEEHIRGLRQWVGQSKTKAEKNKAMGLSMSENSCQLCAVERLAFEPTPIYCTPCGARVKRNAMHYTVVAGESRHYVCIPCYNEARANTVSVDGTPVPKSRFEKKKNDEEVEESWVQCDKCQAWQHQICALFNGRRNHGQAEYTCPNCYIQEVEQGERKPVSQNVILGAKSLPASTLSNHLEQRLFKKLKQERQERARLQGKSYEEVPGADSLVIRVVASVDKILEVKPRFLDIFREDNYSSEFPYKSKAILLFQKIEGVEVCLFGMYVQEFGTDSASPNQRRVYLSYLDSVKYFRPDVRTVSGEALRTFVYHEILIGYLDYCKKRGFSSCYIWACPPLKGEDYILYCHPEIQKTPKTDKLREWYLAMLKKASKEKVVVECTNFYDHFFVQSGECRAKVTAARLPYFDGDYWPGAAEDLIDQMSQEEDGKKSNRKLMPKKVISKRALKAVGQLDLSVNASKDLLLMHKLGEIILPMKEDFIMVHLQHCCKHCCTLMVSGNRWVCNQCKNFQICDKCHEVEENRVEKEKHPVNQKEKHVLYPVAIDNIPTEIKDNDDILESEFFDTRQAFLSLCQGNHYQYDTLRRAKHSSMMILYHLHNPTVPAFAMACAICQQELETAQGWRCEVCPDYDVCNACYSKGINHPHSIISRPSATDSVVQNTQTNQIQNAQLREVLLHVMTCCTAQCQYPRCRVIKGLIRHGLVCKTRGCIACKKMWSLFRLHSRNCRDPQCKVPKCRELRAHFSRKQQQADSRRRAAVMEMVRQRAADTTASTPE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
745	Phosphorylation	VVDDLQPSPKRQKVE EECCCCCCCCCCCCC	30.05	30291188

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of HAC5_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HAC5_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HAC5_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of HAC5_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HAC5_ARATH

Related Literatures of Post-Translational Modification