RGA_ARATH - dbPTM
RGA_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RGA_ARATH
UniProt AC Q9SLH3
Protein Name DELLA protein RGA
Gene Name RGA
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 587
Subcellular Localization Nucleus .
Protein Description Probable transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes. Positively regulates XERICO expression in seeds. Upon GA application, it is degraded by the proteasome, allowing the GA signaling pathway. Compared to other DELLA proteins, it is the most sensitive to GA application. No effect of the BOI proteins on its stability. Its activity is probably regulated by other phytohormones such as auxin and ethylene, attenuation of auxin transport delaying its GA-induced degradation..
Protein Sequence MKRDHHQFQGRLSNHGTSSSSSSISKDKMMMVKKEEDGGGNMDDELLAVLGYKVRSSEMAEVALKLEQLETMMSNVQEDGLSHLATDTVHYNPSELYSWLDNMLSELNPPPLPASSNGLDPVLPSPEICGFPASDYDLKVIPGNAIYQFPAIDSSSSSNNQNKRLKSCSSPDSMVTSTSTGTQIGGVIGTTVTTTTTTTTAAGESTRSVILVDSQENGVRLVHALMACAEAIQQNNLTLAEALVKQIGCLAVSQAGAMRKVATYFAEALARRIYRLSPPQNQIDHCLSDTLQMHFYETCPYLKFAHFTANQAILEAFEGKKRVHVIDFSMNQGLQWPALMQALALREGGPPTFRLTGIGPPAPDNSDHLHEVGCKLAQLAEAIHVEFEYRGFVANSLADLDASMLELRPSDTEAVAVNSVFELHKLLGRPGGIEKVLGVVKQIKPVIFTVVEQESNHNGPVFLDRFTESLHYYSTLFDSLEGVPNSQDKVMSEVYLGKQICNLVACEGPDRVERHETLSQWGNRFGSSGLAPAHLGSNAFKQASMLLSVFNSGQGYRVEESNGCLMLGWHTRPLITTSAWKLSTAAY
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
13PhosphorylationHQFQGRLSNHGTSSS
CCCCCCCCCCCCCCC		25.9728295753
17O-linked_GlycosylationGRLSNHGTSSSSSSI
CCCCCCCCCCCCCCC		20.2026773002
18O-linked_GlycosylationRLSNHGTSSSSSSIS
CCCCCCCCCCCCCCC		32.5826773002
18PhosphorylationRLSNHGTSSSSSSIS
CCCCCCCCCCCCCCC		32.5819880383
19PhosphorylationLSNHGTSSSSSSISK
CCCCCCCCCCCCCCC		33.7928295753
20O-linked_GlycosylationSNHGTSSSSSSISKD
CCCCCCCCCCCCCCC		33.7226773002
21PhosphorylationNHGTSSSSSSISKDK
CCCCCCCCCCCCCCC		30.0123111157
22PhosphorylationHGTSSSSSSISKDKM
CCCCCCCCCCCCCCE		33.3728295753
23PhosphorylationGTSSSSSSISKDKMM
CCCCCCCCCCCCCEE		32.5928295753
25PhosphorylationSSSSSSISKDKMMMV
CCCCCCCCCCCEEEE		36.4328295753
56O-linked_GlycosylationVLGYKVRSSEMAEVA
HHCEEECCHHHHHHH		33.3726773002
57O-linked_GlycosylationLGYKVRSSEMAEVAL
HCEEECCHHHHHHHH		22.3426773002
82O-linked_GlycosylationNVQEDGLSHLATDTV
HCCCCHHHHHCCCCC		23.2226773002
115O-linked_GlycosylationNPPPLPASSNGLDPV
CCCCCCCCCCCCCCC		23.5426773002
116O-linked_GlycosylationPPPLPASSNGLDPVL
CCCCCCCCCCCCCCC		36.7026773002
176O-linked_GlycosylationSSPDSMVTSTSTGTQ
CCCCCCCEECCCCCE		20.0426773002
177O-linked_GlycosylationSPDSMVTSTSTGTQI
CCCCCCEECCCCCEE		14.6726773002
178O-linked_GlycosylationPDSMVTSTSTGTQIG
CCCCCEECCCCCEEC		22.4226773002
179O-linked_GlycosylationDSMVTSTSTGTQIGG
CCCCEECCCCCEECC		25.3026773002
193O-linked_GlycosylationGVIGTTVTTTTTTTT
CEEEEEEEEEEEEEE		19.1426773002
253O-linked_GlycosylationQIGCLAVSQAGAMRK
HHCHHHHHCCCHHHH		14.5426773002
527O-linked_GlycosylationQWGNRFGSSGLAPAH
HHHHCCCCCCCCCCC		20.6526773002
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
-KUbiquitinationE3 ubiquitin ligaseGID2Q9STX3
PMID:22199232
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RGA_ARATH !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RGA_ARATH !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PIF3_ARATHPIF3physical
18216857
PIF4_ARATHPIF4physical
18216857
PIF4_ARATHPIF4physical
20093430
PIF1_ARATHPIL5physical
20093430
SPT_ARATHSPTphysical
20093430
PIF6_ARATHPIL2physical
20093430
PSA7A_ARATHPAD1physical
21798944
FRL1A_ARATHFRL1physical
21798944
AB8I_ARATHABC1physical
21798944
SF3B6_ARATHAT5G12190physical
21798944
BZR1_ARATHBZR1physical
22820377
BZR1_ARATHBZR1physical
23033541
SUMO1_ARATHSUMO1physical
24434138
SUMO2_ARATHSUMO2physical
24434138
RAP23_ARATHEBPphysical
25118255
TIF6B_ARATHJAZ3physical
21145503
TIF7_ARATHTIFY7physical
21145503
TI10A_ARATHJAZ1physical
21145503
GID1A_ARATHGID1Aphysical
25761145
TMKL1_ARATHTMKL1physical
21423366
GL1_ARATHMYB0physical
24659329
EGL1_ARATHEGL3physical
24659329
GL3_ARATHGL3physical
24659329
TCP8_ARATHAT1G58100physical
25127215
TCP9_ARATHAT2G45680physical
25127215
TCP14_ARATHTCP14physical
25127215
TCP15_ARATHAT1G69690physical
25127215
TCP20_ARATHTCP20physical
25127215
TCP22_ARATHAT1G72010physical
25127215
TCP23_ARATHAT1G35560physical
25127215
ARFF_ARATHARF6physical
24867218
ARFG_ARATHNPH4physical
24867218
ARFH_ARATHARF8physical
24867218
IDD3_ARATHMGPphysical
24821766
IDD10_ARATHJKDphysical
24821766
NFYC3_ARATHNF-YC3physical
25105952
NFYC9_ARATHNF-YC9physical
25105952
NFYA1_ARATHNF-YA1physical
25105952
NFYA2_ARATHNF-YA2physical
25105952
NFYB2_ARATHNF-YB2physical
25105952
ATML1_ARATHATML1physical
24989044
PDF2_ARATHPDF2physical
24989044
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RGA_ARATH

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Related Literatures of Post-Translational Modification

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