PDF2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PDF2_ARATH
• UniProt AC: Q93V99
• Protein Name: Homeobox-leucine zipper protein PROTODERMAL FACTOR 2
• Gene Name: PDF2
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 743
• Subcellular Localization: Nucleus .
• Protein Description: Probable transcription factor that binds to the L1 box DNA sequence 5'-TAAATG[CT]A-3'. Plays a role in maintaining the identity of L1 cells, possibly by interacting with their L1 box or other target-gene promoters. Functionally redundant to ATML1..
• Protein Sequence: MYHPNMFESHHMFDMTPKSTSDNDLGITGSREDDFETKSGTEVTTENPSGEELQDPSQRPNKKKRYHRHTQRQIQELESFFKECPHPDDKQRKELSRDLNLEPLQVKFWFQNKRTQMKAQSERHENQILKSDNDKLRAENNRYKEALSNATCPNCGGPAAIGEMSFDEQHLRIENARLREEIDRISAIAAKYVGKPLGSSFAPLAIHAPSRSLDLEVGNFGNQTGFVGEMYGTGDILRSVSIPSETDKPIIVELAVAAMEELVRMAQTGDPLWLSTDNSVEILNEEEYFRTFPRGIGPKPLGLRSEASRQSAVVIMNHINLVEILMDVNQWSCVFSGIVSRALTLEVLSTGVAGNYNGALQVMTAEFQVPSPLVPTRENYFVRYCKQHSDGSWAVVDVSLDSLRPSTPILRTRRRPSGCLIQELPNGYSKVTWIEHMEVDDRSVHNMYKPLVQSGLAFGAKRWVATLERQCERLASSMASNIPGDLSVITSPEGRKSMLKLAERMVMSFCSGVGASTAHAWTTMSTTGSDDVRVMTRKSMDDPGRPPGIVLSAATSFWIPVAPKRVFDFLRDENSRKEWDILSNGGMVQEMAHIANGHEPGNCVSLLRVNSGNSSQSNMLILQESCTDASGSYVIYAPVDIVAMNVVLSGGDPDYVALLPSGFAILPDGSVGGGDGNQHQEMVSTTSSGSCGGSLLTVAFQILVDSVPTAKLSLGSVATVNSLIKCTVERIKAAVSCDVGGGA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
19	Phosphorylation	MFDMTPKSTSDNDLG CCCCCCCCCCCCCCC	34.05	29654922
20	Phosphorylation	FDMTPKSTSDNDLGI CCCCCCCCCCCCCCC	46.34	29654922
21	Phosphorylation	DMTPKSTSDNDLGIT CCCCCCCCCCCCCCC	41.32	30291188
39	Phosphorylation	EDDFETKSGTEVTTE CCCCCCCCCCEEEEC	59.37	25561503
49	Phosphorylation	EVTTENPSGEELQDP EEEECCCCCCCCCCC	71.11	30291188
121	Phosphorylation	RTQMKAQSERHENQI HHHHHHHHHHHHHHH	41.27	19880383
131	Phosphorylation	HENQILKSDNDKLRA HHHHHHHCHHHHHHH	37.90	24894044
336	Phosphorylation	NQWSCVFSGIVSRAL CHHHHHHHHHHHHHH	13.76	28011693
476	Phosphorylation	RQCERLASSMASNIP HHHHHHHHHHHHCCC	25.82	23776212
477	Phosphorylation	QCERLASSMASNIPG HHHHHHHHHHHCCCC	16.86	23776212
480	Phosphorylation	RLASSMASNIPGDLS HHHHHHHHCCCCCCE	27.01	23776212
487	Phosphorylation	SNIPGDLSVITSPEG HCCCCCCEEEECCCH	19.06	23776212
490	Phosphorylation	PGDLSVITSPEGRKS CCCCEEEECCCHHHH	35.75	23776212
491	Phosphorylation	GDLSVITSPEGRKSM CCCEEEECCCHHHHH	15.16	23776212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PDF2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PDF2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PDF2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RBS2B_ARATH	AT5G38420	physical	21798944
ATML1_ARATH	ATML1	physical	24147836
PDF2_ARATH	PDF2	physical	24147836

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.