ATML1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ATML1_ARATH
• UniProt AC: Q8RWU4
• Protein Name: Homeobox-leucine zipper protein MERISTEM L1
• Gene Name: ATML1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 762
• Subcellular Localization: Nucleus .
• Protein Description: Probable transcription factor involved in cell specification and pattern formation during embryogenesis. Binds to the L1 box DNA sequence 5'-TAAATG[CT]A-3'. Plays a role in maintaining the identity of L1 cells, possibly by interacting with their L1 box or other target-gene promoters. Functionally redundant to PDF2..
• Protein Sequence: MYHPNMFESHHHMFDMTPKNSENDLGITGSHEEDFETKSGAEVTMENPLEEELQDPNQRPNKKKRYHRHTQRQIQELESFFKECPHPDDKQRKELSRELSLEPLQVKFWFQNKRTQMKAQHERHENQILKSENDKLRAENNRYKDALSNATCPNCGGPAAIGEMSFDEQHLRIENARLREEIDRISAIAAKYVGKPLMANSSSFPQLSSSHHIPSRSLDLEVGNFGNNNNSHTGFVGEMFGSSDILRSVSIPSEADKPMIVELAVAAMEELVRMAQTGDPLWVSSDNSVEILNEEEYFRTFPRGIGPKPIGLRSEASRESTVVIMNHINLIEILMDVNQWSSVFCGIVSRALTLEVLSTGVAGNYNGALQVMTAEFQVPSPLVPTRENYFVRYCKQHSDGIWAVVDVSLDSLRPSPITRSRRRPSGCLIQELQNGYSKVTWVEHIEVDDRSVHNMYKPLVNTGLAFGAKRWVATLDRQCERLASSMASNIPACDLSVITSPEGRKSMLKLAERMVMSFCTGVGASTAHAWTTLSTTGSDDVRVMTRKSMDDPGRPPGIVLSAATSFWIPVAPKRVFDFLRDENSRSEWDILSNGGLVQEMAHIANGRDPGNSVSLLRVNSGNSGQSNMLILQESCTDASGSYVIYAPVDIIAMNVVLSGGDPDYVALLPSGFAILPDGSARGGGGSANASAGAGVEGGGEGNNLEVVTTTGSCGGSLLTVAFQILVDSVPTAKLSLGSVATVNSLIKCTVERIKAALACDGA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
28	Phosphorylation	SENDLGITGSHEEDF CCCCCCCCCCCHHHH	30.73	27531888
30	Phosphorylation	NDLGITGSHEEDFET CCCCCCCCCHHHHCC	21.05	30291188
39	Phosphorylation	EEDFETKSGAEVTME HHHHCCCCCCEEEEC	51.13	27545962
44	Phosphorylation	TKSGAEVTMENPLEE CCCCCEEEECCCCHH	15.40	27545962
100	Phosphorylation	KELSRELSLEPLQVK HHHHHHHCCCHHHHH	26.40	30291188
203	Phosphorylation	PLMANSSSFPQLSSS CCCCCCCCCCCCCCC	40.54	29654922

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ATML1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ATML1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ATML1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PDF2_ARATH	PDF2	physical	24147836
PDF2_ARATH	PDF2	physical	24989044

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.