ARFG_ARATH - dbPTM
ARFG_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ARFG_ARATH
UniProt AC P93022
Protein Name Auxin response factor 7
Gene Name ARF7
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 1164
Subcellular Localization Nucleus.
Protein Description Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Act as a transcriptional activator of several tropic stimulus-induced (TSI) genes, including SAUR50. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Required for differential growth responses of aerial tissues. Involved in ethylene responses. Regulates lateral root formation through direct regulation of LBD16 and/or LBD29. Functionally redundant with ARF19. Mediates embryo axis formation and vascular tissues differentiation. Functionally redundant with ARF5..
Protein Sequence MKAPSSNGVSPNPVEGERRNINSELWHACAGPLISLPPAGSLVVYFPQGHSEQVAASMQKQTDFIPSYPNLPSKLICMLHNVTLNADPETDEVYAQMTLQPVNKYDRDALLASDMGLKLNRQPNEFFCKTLTASDTSTHGGFSVPRRAAEKIFPALDFSMQPPCQELVAKDIHDNTWTFRHIYRGQPKRHLLTTGWSVFVSTKRLFAGDSVLFIRDGKAQLLLGIRRANRQQPALSSSVISSDSMHIGVLAAAAHANANNSPFTIFYNPRAAPAEFVVPLAKYTKAMYAQVSLGMRFRMIFETEECGVRRYMGTVTGISDLDPVRWKNSQWRNLQIGWDESAAGDRPSRVSVWDIEPVLTPFYICPPPFFRPRFSGQPGMPDDETDMESALKRAMPWLDNSLEMKDPSSTIFPGLSLVQWMNMQQQNGQLPSAAAQPGFFPSMLSPTAALHNNLGGTDDPSKLLSFQTPHGGISSSNLQFNKQNQQAPMSQLPQPPTTLSQQQQLQQLLHSSLNHQQQQSQSQQQQQQQQLLQQQQQLQSQQHSNNNQSQSQQQQQLLQQQQQQQLQQQHQQPLQQQTQQQQLRTQPLQSHSHPQPQQLQQHKLQQLQVPQNQLYNGQQAAQQHQSQQASTHHLQPQLVSGSMASSVITPPSSSLNQSFQQQQQQSKQLQQAHHHLGASTSQSSVIETSKSSSNLMSAPPQETQFSRQVEQQQPPGLNGQNQQTLLQQKAHQAQAQQIFQQSLLEQPHIQFQLLQRLQQQQQQQFLSPQSQLPHHQLQSQQLQQLPTLSQGHQFPSSCTNNGLSTLQPPQMLVSRPQEKQNPPVGGGVKAYSGITDGGDAPSSSTSPSTNNCQISSSGFLNRSQSGPAILIPDAAIDMSGNLVQDLYSKSDMRLKQELVGQQKSKASLTDHQLEASASGTSYGLDGGENNRQQNFLAPTFGLDGDSRNSLLGGANVDNGFVPDTLLSRGYDSQKDLQNMLSNYGGVTNDIGTEMSTSAVRTQSFGVPNVPAISNDLAVNDAGVLGGGLWPAQTQRMRTYTKVQKRGSVGRSIDVNRYRGYDELRHDLARMFGIEGQLEDPQTSDWKLVYVDHENDILLVGDDPWEEFVNCVQSIKILSSAEVQQMSLDGNFAGVPVTNQACSGGDSGNAWRGHYDDNSATSFNR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
193PhosphorylationQPKRHLLTTGWSVFV
CCCCEEECCCCEEEE
29.6219880383
194PhosphorylationPKRHLLTTGWSVFVS
CCCEEECCCCEEEEE
36.3019880383
201PhosphorylationTGWSVFVSTKRLFAG
CCCEEEEEECCCCCC
19.4219880383
202PhosphorylationGWSVFVSTKRLFAGD
CCEEEEEECCCCCCC
18.1919880383
916PhosphorylationTDHQLEASASGTSYG
CHHHHHHHHCCCCCC
17.3730407730
918PhosphorylationHQLEASASGTSYGLD
HHHHHHHCCCCCCCC
39.8630407730
920PhosphorylationLEASASGTSYGLDGG
HHHHHCCCCCCCCCC
19.1130407730
921PhosphorylationEASASGTSYGLDGGE
HHHHCCCCCCCCCCC
22.2630407730
922PhosphorylationASASGTSYGLDGGEN
HHHCCCCCCCCCCCC
22.8830407730
1057PhosphorylationRSIDVNRYRGYDELR
CCCCCCCCCCHHHHH
11.8219880383
1158PhosphorylationRGHYDDNSATSFNR-
CCCCCCCCCCCCCC-
39.6630407730
1160PhosphorylationHYDDNSATSFNR---
CCCCCCCCCCCC---
33.4030407730
1161PhosphorylationYDDNSATSFNR----
CCCCCCCCCCC----
21.9030407730

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ARFG_ARATH !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ARFG_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ARFG_ARATH !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ARFG_ARATHNPH4physical
16854942
ARFE_ARATHMPphysical
14973283
IAA12_ARATHIAA12physical
14973283
ARFG_ARATHNPH4physical
24706860
IAA11_ARATHIAA11physical
21734647
IAA7_ARATHIAA7physical
21734647
IAA3_ARATHSHY2physical
21734647
IAA2_ARATHIAA2physical
21734647
IAA1_ARATHIAA1physical
21734647
IAA27_ARATHPAP2physical
21734647
IAA19_ARATHIAA19physical
21734647
IAA17_ARATHAXR3physical
21734647
IAA1_ARATHIAA1physical
25566309
IAA2_ARATHIAA2physical
25566309
IAA3_ARATHSHY2physical
25566309
IAA4_ARATHATAUX2-11physical
25566309
IAA5_ARATHIAA5physical
25566309
IAA6_ARATHIAA6physical
25566309
IAA8_ARATHIAA8physical
25566309
IAA9_ARATHIAA9physical
25566309
IAA10_ARATHIAA10physical
25566309
IAA11_ARATHIAA11physical
25566309
IAA12_ARATHIAA12physical
25566309
IAA13_ARATHIAA13physical
25566309
IAA14_ARATHIAA14physical
25566309
IAA15_ARATHIAA15physical
25566309
IAA16_ARATHIAA16physical
25566309
IAA17_ARATHAXR3physical
25566309
IAA18_ARATHIAA18physical
25566309
IAA19_ARATHIAA19physical
25566309
IAA20_ARATHIAA20physical
25566309
IAA26_ARATHPAP1physical
25566309
IAA27_ARATHPAP2physical
25566309
IAA28_ARATHIAA28physical
25566309
IAA29_ARATHIAA29physical
25566309
IAA30_ARATHIAA30physical
25566309
IAA31_ARATHIAA31physical
25566309
IAA32_ARATHIAA32physical
25566309
IAA33_ARATHIAA33physical
25566309
IAA34_ARATHIAA34physical
25566309
IAA19_ARATHIAA19physical
14729917
IAA1_ARATHIAA1physical
14729917
IAA6_ARATHIAA6physical
14729917
IAA13_ARATHIAA13physical
14729917
ARFG_ARATHNPH4physical
25839233

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ARFG_ARATH

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Related Literatures of Post-Translational Modification

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