IAA18_ARATH - dbPTM
IAA18_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID IAA18_ARATH
UniProt AC O24408
Protein Name Auxin-responsive protein IAA18
Gene Name IAA18
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 267
Subcellular Localization Nucleus.
Protein Description Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression..
Protein Sequence MEGYSRNGEISPKLLDLMIPQERRNWFHDEKNSVFKTEEKKLELKLGPPGEEDDDESMIRHMKKEPKDKSILSLAGKYFSPSSTKTTSHKRTAPGPVVGWPPVRSFRKNLASGSSSKLGNDSTTSNGVTLKNQKCDAAAKTTEPKRQGGMFVKINMYGVPIGRKVDLSAHNSYEQLSFTVDKLFRGLLAAQRDFPSSIEDEKPITGLLDGNGEYTLTYEDNEGDKMLVGDVPWQMFVSSVKRLRVIKTSEISSALTYGNGKQEKMRR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of IAA18_ARATH !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of IAA18_ARATH !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of IAA18_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of IAA18_ARATH !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
IAA11_ARATHIAA11physical
21798944
PP216_ARATHEMB2750physical
21798944
TIG_ARATHAT5G55220physical
21798944
IAA19_ARATHIAA19physical
21798944
IAA2_ARATHIAA2physical
21798944
IAA31_ARATHIAA31physical
21798944
IAA7_ARATHIAA7physical
21798944
IAA1_ARATHIAA1physical
21798944
IAA8_ARATHIAA8physical
21798944
ARFI_ARATHARF9physical
21734647
ARFS_ARATHARF19physical
21734647
IAA1_ARATHIAA1physical
21734647
IAA10_ARATHIAA10physical
21734647
IAA12_ARATHIAA12physical
21734647
IAA17_ARATHAXR3physical
21734647
IAA31_ARATHIAA31physical
21734647
IAA28_ARATHIAA28physical
21734647
IAA20_ARATHIAA20physical
21734647
ARFE_ARATHMPphysical
21734647
ARFF_ARATHARF6physical
21734647
ARFG_ARATHNPH4physical
21734647
ARFH_ARATHARF8physical
21734647

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of IAA18_ARATH

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Related Literatures of Post-Translational Modification

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