ARFE_ARATH - dbPTM
ARFE_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ARFE_ARATH
UniProt AC P93024
Protein Name Auxin response factor 5
Gene Name ARF5
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 902
Subcellular Localization Nucleus.
Protein Description Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Mediates embryo axis formation and vascular tissues differentiation. Functionally redundant with ARF7. May be necessary to counteract AMP1 activity..
Protein Sequence MMASLSCVEDKMKTSCLVNGGGTITTTTSQSTLLEEMKLLKDQSGTRKPVINSELWHACAGPLVCLPQVGSLVYYFSQGHSEQVAVSTRRSATTQVPNYPNLPSQLMCQVHNVTLHADKDSDEIYAQMSLQPVHSERDVFPVPDFGMLRGSKHPTEFFCKTLTASDTSTHGGFSVPRRAAEKLFPPLDYSAQPPTQELVVRDLHENTWTFRHIYRGQPKRHLLTTGWSLFVGSKRLRAGDSVLFIRDEKSQLMVGVRRANRQQTALPSSVLSADSMHIGVLAAAAHATANRTPFLIFYNPRACPAEFVIPLAKYRKAICGSQLSVGMRFGMMFETEDSGKRRYMGTIVGISDLDPLRWPGSKWRNLQVEWDEPGCNDKPTRVSPWDIETPESLFIFPSLTSGLKRQLHPSYFAGETEWGSLIKRPLIRVPDSANGIMPYASFPSMASEQLMKMMMRPHNNQNVPSFMSEMQQNIVMGNGGLLGDMKMQQPLMMNQKSEMVQPQNKLTVNPSASNTSGQEQNLSQSMSAPAKPENSTLSGCSSGRVQHGLEQSMEQASQVTTSTVCNEEKVNQLLQKPGASSPVQADQCLDITHQIYQPQSDPINGFSFLETDELTSQVSSFQSLAGSYKQPFILSSQDSSAVVLPDSTNSPLFHDVWDTQLNGLKFDQFSPLMQQDLYASQNICMSNSTTSNILDPPLSNTVLDDFCAIKDTDFQNHPSGCLVGNNNTSFAQDVQSQITSASFADSQAFSRQDFPDNSGGTGTSSSNVDFDDCSLRQNSKGSSWQKIATPRVRTYTKVQKTGSVGRSIDVTSFKDYEELKSAIECMFGLEGLLTHPQSSGWKLVYVDYESDVLLVGDDPWEEFVGCVRCIRILSPTEVQQMSEEGMKLLNSAGINDLKTSVS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
346PhosphorylationGKRRYMGTIVGISDL
CCEEEEEEEEECCCC		8.9226091701
432PhosphorylationPLIRVPDSANGIMPY
CEEECCCCCCCCCCC		19.9823776212
439PhosphorylationSANGIMPYASFPSMA
CCCCCCCCCCCCHHH		9.4823776212
441PhosphorylationNGIMPYASFPSMASE
CCCCCCCCCCHHHHH		31.6723776212
444PhosphorylationMPYASFPSMASEQLM
CCCCCCCHHHHHHHH		25.6023776212
447PhosphorylationASFPSMASEQLMKMM
CCCCHHHHHHHHHHH		19.7523776212
499SulfoxidationMMNQKSEMVQPQNKL
CCCCCCCCCCCCCCE		4.3523289948
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ARFE_ARATH !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ARFE_ARATH !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ARFE_ARATH !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ARFG_ARATHNPH4physical
16854942
ARFG_ARATHNPH4physical
14973283
IAA12_ARATHIAA12physical
14973283
BRX_ARATHBRXphysical
21149702
ARFR_ARATHARF18physical
22096563
ARFE_ARATHMPphysical
24485461
ARFE_ARATHMPphysical
21734647
IAA12_ARATHIAA12physical
21734647
IAA2_ARATHIAA2physical
21734647
IAA3_ARATHSHY2physical
21734647
IAA17_ARATHAXR3physical
21734647
IAA8_ARATHIAA8physical
21734647
IAA11_ARATHIAA11physical
21734647
IAA7_ARATHIAA7physical
21734647
IAA34_ARATHIAA34physical
21734647
IAA31_ARATHIAA31physical
21734647
IAA29_ARATHIAA29physical
21734647
IAA28_ARATHIAA28physical
21734647
IAA32_ARATHIAA32physical
21734647
IAA1_ARATHIAA1physical
25566309
IAA2_ARATHIAA2physical
25566309
IAA3_ARATHSHY2physical
25566309
IAA4_ARATHATAUX2-11physical
25566309
IAA5_ARATHIAA5physical
25566309
IAA6_ARATHIAA6physical
25566309
IAA7_ARATHIAA7physical
25566309
IAA8_ARATHIAA8physical
25566309
IAA9_ARATHIAA9physical
25566309
IAA10_ARATHIAA10physical
25566309
IAA11_ARATHIAA11physical
25566309
IAA12_ARATHIAA12physical
25566309
IAA13_ARATHIAA13physical
25566309
IAA14_ARATHIAA14physical
25566309
IAA15_ARATHIAA15physical
25566309
IAA16_ARATHIAA16physical
25566309
IAA17_ARATHAXR3physical
25566309
IAA18_ARATHIAA18physical
25566309
IAA19_ARATHIAA19physical
25566309
IAA20_ARATHIAA20physical
25566309
IAA26_ARATHPAP1physical
25566309
IAA27_ARATHPAP2physical
25566309
IAA28_ARATHIAA28physical
25566309
IAA29_ARATHIAA29physical
25566309
IAA30_ARATHIAA30physical
25566309
IAA31_ARATHIAA31physical
25566309
IAA32_ARATHIAA32physical
25566309
IAA33_ARATHIAA33physical
25566309
IAA34_ARATHIAA34physical
25566309
IAA19_ARATHIAA19physical
14729917
IAA1_ARATHIAA1physical
14729917
IAA6_ARATHIAA6physical
14729917
IAA13_ARATHIAA13physical
14729917
ARFE_ARATHMPphysical
25512488
ARFE_ARATHMPphysical
24710426
IAA12_ARATHIAA12physical
24710426
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ARFE_ARATH

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory