IAA29_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: IAA29_ARATH
• UniProt AC: Q93WC4
• Protein Name: Auxin-responsive protein IAA29
• Gene Name: IAA29
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 251
• Subcellular Localization: Nucleus.
• Protein Description: Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression..
• Protein Sequence: MELDLGLSLSPHKSSKLGFNFDLNKHCAIEGAASCLGTEKLRFEATFGLGNVEENCYMPKQRLFALNGQPNEEDEDPLESESSIVYDDEEENSEVVGWPPVKTCMIKYGSYHHRHIRNHHHCPYHHRGRRITAMNNNISNPTTATVGSSSSSSISSRSSMYVKVKMDGVAIARKVDIKLFNSYESLTNSLITMFTEYEDCDREDTNYTFTFQGKEGDWLLRGDVTWKIFAESVHRISIIRDRPCAYTRCLF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
132	Phosphorylation	HHRGRRITAMNNNIS CCCCCCEEEECCCCC	20.31	22074104
139	Phosphorylation	TAMNNNISNPTTATV EEECCCCCCCCCCCC	38.59	22074104
142	Phosphorylation	NNNISNPTTATVGSS CCCCCCCCCCCCCCC	33.06	22074104
143	Phosphorylation	NNISNPTTATVGSSS CCCCCCCCCCCCCCC	22.91	22074104
145	Phosphorylation	ISNPTTATVGSSSSS CCCCCCCCCCCCCCC	24.25	22074104
148	Phosphorylation	PTTATVGSSSSSSIS CCCCCCCCCCCCCCC	23.78	22074104
156	Phosphorylation	SSSSSISSRSSMYVK CCCCCCCCCCCCEEE	34.22	22074104
158	Phosphorylation	SSSISSRSSMYVKVK CCCCCCCCCCEEEEE	22.77	22074104
159	Phosphorylation	SSISSRSSMYVKVKM CCCCCCCCCEEEEEE	17.02	22074104
161	Phosphorylation	ISSRSSMYVKVKMDG CCCCCCCEEEEEECC	10.08	22074104
232	Phosphorylation	TWKIFAESVHRISII EEEEEEEEEEEEEEE	21.57	23572148
247	Phosphorylation	RDRPCAYTRCLF--- CCCCCCEEECCC---	9.07	23572148

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of IAA29_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of IAA29_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of IAA29_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ARFG_ARATH	NPH4	physical	23757399
WRK57_ARATH	WRKY57	physical	24424094
ARFS_ARATH	ARF19	physical	21734647
IAA5_ARATH	IAA5	physical	21734647
IAA33_ARATH	IAA33	physical	21734647
ARFG_ARATH	NPH4	physical	21734647
ARFQ_ARATH	ARF17	physical	21734647

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.