TI10A_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TI10A_ARATH
• UniProt AC: Q9LMA8
• Protein Name: Protein TIFY 10A
• Gene Name: TIFY10A
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 253
• Subcellular Localization: Nucleus .
• Protein Description: Repressor of jasmonate responses. Jasmonoyl-isoleucine (JA-Ile) specifically promotes COI1-TIFY10A/JAZ1 interaction. Interacts with COI1 and inositol pentakisphosphate to form a high-affinity jasmonates coreceptor..
• Protein Sequence: MSSSMECSEFVGSRRFTGKKPSFSQTCSRLSQYLKENGSFGDLSLGMACKPDVNGTLGNSRQPTTTMSLFPCEASNMDSMVQDVKPTNLFPRQPSFSSSSSSLPKEDVLKMTQTTRSVKPESQTAPLTIFYAGQVIVFNDFSAEKAKEVINLASKGTANSLAKNQTDIRSNIATIANQVPHPRKTTTQEPIQSSPTPLTELPIARRASLHRFLEKRKDRVTSKAPYQLCDPAKASSNPQTTGNMSWLGLAAEI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
95	Phosphorylation	NLFPRQPSFSSSSSS CCCCCCCCCCCCCCC	29.44	25561503
97	Phosphorylation	FPRQPSFSSSSSSLP CCCCCCCCCCCCCCC	33.38	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
-	K	Ubiquitination	E3 ubiquitin ligase	COI1	O04197	PMID:22199232

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TI10A_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TI10A_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
COI1_ARATH	COI1	physical	18547396
MYC2_ARATH	MYC2	physical	18547396
COI1_ARATH	COI1	physical	17637677
COI1_ARATH	COI1	physical	19717617
NINJA_ARATH	NINJA	physical	20360743
COI1_ARATH	COI1	physical	20360743
TIF3B_ARATH	JAZ12	physical	20360743
MYC4_ARATH	AT4G17880	physical	21321051
MYC2_ARATH	MYC2	physical	21321051
MYC3_ARATH	AT5G46760	physical	21321051
MYB21_ARATH	MYB21	physical	21447791
MYB24_ARATH	MYB24	physical	21447791
MYC2_ARATH	MYC2	physical	21335373
MYC3_ARATH	AT5G46760	physical	21335373
MYC4_ARATH	AT4G17880	physical	21335373
EIN3_ARATH	EIN3	physical	21737749
HDA6_ARATH	HDA6	physical	21737749
CSN5A_ARATH	CSN5A	physical	21798944
TI10A_ARATH	JAZ1	physical	21798944
TIF5A_ARATH	JAZ8	physical	21798944
ICE1_ARATH	ICE1	physical	23933884
SCRM2_ARATH	SCRM2	physical	23933884
RGA_ARATH	RGA1	physical	21145503
MYC2_ARATH	MYC2	physical	21145503
MYC2_ARATH	MYC2	physical	19309455
TI10A_ARATH	JAZ1	physical	19309455
TIF6A_ARATH	JAZ4	physical	19309455
TIF5A_ARATH	JAZ8	physical	19309455
TIF7_ARATH	TIFY7	physical	19309455
BH013_ARATH	AT1G01260	physical	23935516
AIB_ARATH	AIB	physical	23935516
BH003_ARATH	AT4G16430	physical	23935516
BH014_ARATH	AT4G00870	physical	23935516
MYC2_ARATH	MYC2	physical	23169619
TI10A_ARATH	JAZ1	physical	19151223
TI10B_ARATH	TIFY10B	physical	19151223
TIF5A_ARATH	JAZ8	physical	19151223
TIF9_ARATH	JAZ10	physical	19151223
TIF3A_ARATH	JAZ11	physical	19151223
BH028_ARATH	NIG1	physical	26002869
MYC3_ARATH	AT5G46760	physical	25817565
MYC2_ARATH	MYC2	physical	25817565
RAP27_ARATH	RAP2.7	physical	26410299
TOE2_ARATH	TOE2	physical	26410299

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.