NINJA_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NINJA_ARATH
• UniProt AC: Q9SV55
• Protein Name: AFP homolog 2 {ECO:0000303|PubMed:18484180}
• Gene Name: AFPH2 {ECO:0000303|PubMed:18484180}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 425
• Subcellular Localization: Nucleus .
• Protein Description: Acts as a transcriptional repressor. Negative regulator of jasmonate responses. Connects the JAZ proteins and the non-JAZ protein TIFY8 with the TOPLESS corepressors..
• Protein Sequence: MDDDNGLELSLGLSCGGSTGKAKGNNNNNAGSSSENYRAEGGDRSAKVIDDFKNFLHPTSQRPAEPSSGSQRSDSGQQPPQNFFNDLSKAPTTEAEASTKPLWVEDESRKEAGNKRKFGFPGMNDDKKKEKDSSHVDMHEKKTKASHVSTATDEGSTAENEDVAESEVGGGSSSNHAKEVVRPPTDTNIVDNLTGQRRSNHGGSGTEEFTMRNMSYTVPFTVHPQNVVTSMPYSLPTKESGQHAAATSLLQPNANAGNLPIMFGYSPVQLPMLDKDGSGGIVALSQSPFAGRVPSNSATAKGEGKQPVAEEGSSEDASERPTGDNSNLNTAFSFDFSAIKPGMAADVKFGGSGARPNLPWVSTTGSGPHGRTISGVTYRYNANQIKIVCACHGSHMSPEEFVRHASEEYVSPESSMGMTAASAHT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
32	Phosphorylation	NNNNNAGSSSENYRA CCCCCCCCCCCCCCC	28.42	29654922
67	Phosphorylation	SQRPAEPSSGSQRSD CCCCCCCCCCCCCCC	38.54	29654922
68	Phosphorylation	QRPAEPSSGSQRSDS CCCCCCCCCCCCCCC	53.86	25561503
70	Phosphorylation	PAEPSSGSQRSDSGQ CCCCCCCCCCCCCCC	25.11	25561503
73	Phosphorylation	PSSGSQRSDSGQQPP CCCCCCCCCCCCCCC	28.61	23776212
75	Phosphorylation	SGSQRSDSGQQPPQN CCCCCCCCCCCCCCC	39.48	23776212
88	Phosphorylation	QNFFNDLSKAPTTEA CCCCHHHHCCCCCCC	29.63	23776212
146	Phosphorylation	HEKKTKASHVSTATD HHHHHHHHHCEECCC	26.44	30407730
149	Phosphorylation	KTKASHVSTATDEGS HHHHHHCEECCCCCC	13.60	30407730
150	Phosphorylation	TKASHVSTATDEGST HHHHHCEECCCCCCC	32.27	30407730
152	Phosphorylation	ASHVSTATDEGSTAE HHHCEECCCCCCCCC	34.37	30407730
156	Phosphorylation	STATDEGSTAENEDV EECCCCCCCCCCHHH	23.54	23111157
157	Phosphorylation	TATDEGSTAENEDVA ECCCCCCCCCCHHHC	49.17	27545962
166	Phosphorylation	ENEDVAESEVGGGSS CCHHHCCCCCCCCCC	28.04	24601666
172	Phosphorylation	ESEVGGGSSSNHAKE CCCCCCCCCCCCCCC	33.59	24601666
173	Phosphorylation	SEVGGGSSSNHAKEV CCCCCCCCCCCCCCC	38.13	27545962
174	Phosphorylation	EVGGGSSSNHAKEVV CCCCCCCCCCCCCCC	34.04	27531888
278	Phosphorylation	PMLDKDGSGGIVALS CEECCCCCCCEEEEE	43.94	19880383
285	Phosphorylation	SGGIVALSQSPFAGR CCCEEEEECCCCCCC	20.90	30589143
287	Phosphorylation	GIVALSQSPFAGRVP CEEEEECCCCCCCCC	20.71	23111157
297	Phosphorylation	AGRVPSNSATAKGEG CCCCCCCCCCCCCCC	31.19	25561503
299	Phosphorylation	RVPSNSATAKGEGKQ CCCCCCCCCCCCCCC	28.82	25561503
411	Phosphorylation	HASEEYVSPESSMGM HCCHHHCCCHHHCCC	23.27	23111157
414	Phosphorylation	EEYVSPESSMGMTAA HHHCCCHHHCCCCHH	29.07	23111157
422	Phosphorylation	SMGMTAASAHT---- HCCCCHHCCCC----	20.37	30589143
425	Phosphorylation	MTAASAHT------- CCHHCCCC-------	39.77	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NINJA_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NINJA_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NINJA_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TPL_ARATH	TPL	physical	20360743
TIF8_ARATH	TIFY8	physical	24416306
TI10A_ARATH	JAZ1	physical	26320228
TI10B_ARATH	TIFY10B	physical	26320228
TDX_ARATH	TDX	physical	26320228
TIF6A_ARATH	JAZ4	physical	26320228
TI11A_ARATH	JAZ5	physical	26320228
TI11B_ARATH	JAZ6	physical	26320228
TIF7_ARATH	TIFY7	physical	26320228
TIF9_ARATH	JAZ10	physical	26320228
TIF3A_ARATH	JAZ11	physical	26320228
TIF3B_ARATH	JAZ12	physical	26320228

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.