MYC3_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MYC3_ARATH
• UniProt AC: Q9FIP9
• Protein Name: Transcription factor MYC3
• Gene Name: MYC3
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 592
• Subcellular Localization: Nucleus .
• Protein Description: Transcription factor involved in tryptophan, jasmonic acid (JA) and other stress-responsive gene regulation. With MYC2 and MYC4, controls additively subsets of JA-dependent responses. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the G-box (5'-CACGTG-3') of promoters. Activates multiple TIFY/JAZ promoters..
• Protein Sequence: MNGTTSSINFLTSDDDASAAAMEAFIGTNHHSSLFPPPPQQPPQPQFNEDTLQQRLQALIESAGENWTYAIFWQISHDFDSSTGDNTVILGWGDGYYKGEEDKEKKKNNTNTAEQEHRKRVIRELNSLISGGIGVSDESNDEEVTDTEWFFLVSMTQSFVNGVGLPGESFLNSRVIWLSGSGALTGSGCERAGQGQIYGLKTMVCIATQNGVVELGSSEVISQSSDLMHKVNNLFNFNNGGGNNGVEASSWGFNLNPDQGENDPALWISEPTNTGIESPARVNNGNNSNSNSKSDSHQISKLEKNDISSVENQNRQSSCLVEKDLTFQGGLLKSNETLSFCGNESSKKRTSVSKGSNNDEGMLSFSTVVRSAANDSDHSDLEASVVKEAIVVEPPEKKPRKRGRKPANGREEPLNHVEAERQRREKLNQRFYSLRAVVPNVSKMDKASLLGDAISYINELKSKLQQAESDKEEIQKKLDGMSKEGNNGKGCGSRAKERKSSNQDSTASSIEMEIDVKIIGWDVMIRVQCGKKDHPGARFMEALKELDLEVNHASLSVVNDLMIQQATVKMGSQFFNHDQLKVALMTKVGENY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
294	Phosphorylation	NSNSNSKSDSHQISK CCCCCCCCCHHHHHH		25561503
296	Phosphorylation	NSNSKSDSHQISKLE CCCCCCCHHHHHHHH		25561503
308	Phosphorylation	KLEKNDISSVENQNR HHHHCCHHHHHCCCC		30407730
309	Phosphorylation	LEKNDISSVENQNRQ HHHCCHHHHHCCCCH		30407730
339	Phosphorylation	LKSNETLSFCGNESS ECCCCEEEECCCCCC		30291188
371	Phosphorylation	SFSTVVRSAANDSDH EHHHHHHHHHCCCCC		23776212
376	Phosphorylation	VRSAANDSDHSDLEA HHHHHCCCCCHHHHH		23776212
379	Phosphorylation	AANDSDHSDLEASVV HHCCCCCHHHHHHHE		19880383
384	Phosphorylation	DHSDLEASVVKEAIV CCHHHHHHHEEEEEE		23776212
482	Phosphorylation	QKKLDGMSKEGNNGK HHHHHCCCCCCCCCC		19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MYC3_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MYC3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MYC3_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TI10A_ARATH	JAZ1	physical	21335373
TI10B_ARATH	TIFY10B	physical	21335373
TIF6B_ARATH	JAZ3	physical	21335373
TI11A_ARATH	JAZ5	physical	21335373
TI11B_ARATH	JAZ6	physical	21335373
TIF5A_ARATH	JAZ8	physical	21335373
TIF7_ARATH	TIFY7	physical	21335373
TIF9_ARATH	JAZ10	physical	21335373
TIF3A_ARATH	JAZ11	physical	21335373
TIF3B_ARATH	JAZ12	physical	21335373
MYC4_ARATH	AT4G17880	physical	21335373
MYC3_ARATH	AT5G46760	physical	21335373
MYC2_ARATH	MYC2	physical	21335373
MED25_ARATH	PFT1	physical	22822211
TI10A_ARATH	JAZ1	physical	25049362
HY5_ARATH	HY5	physical	19802365
MYB21_ARATH	MYB21	physical	26002869
MYB24_ARATH	MYB24	physical	26002869
TIF7_ARATH	TIFY7	physical	26258305
MED25_ARATH	PFT1	physical	26258305

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.