MYC4_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MYC4_ARATH
• UniProt AC: O49687
• Protein Name: Transcription factor MYC4
• Gene Name: MYC4
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 589
• Subcellular Localization: Nucleus .
• Protein Description: Transcription factor involved in jasmonic acid (JA) gene regulation. With MYC2 and MYC3, controls additively subsets of JA-dependent responses. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the G-box (5'-CACGTG-3') of promoters. Activates multiple TIFY/JAZ promoters..
• Protein Sequence: MSPTNVQVTDYHLNQSKTDTTNLWSTDDDASVMEAFIGGGSDHSSLFPPLPPPPLPQVNEDNLQQRLQALIEGANENWTYAVFWQSSHGFAGEDNNNNNTVLLGWGDGYYKGEEEKSRKKKSNPASAAEQEHRKRVIRELNSLISGGVGGGDEAGDEEVTDTEWFFLVSMTQSFVKGTGLPGQAFSNSDTIWLSGSNALAGSSCERARQGQIYGLQTMVCVATENGVVELGSSEIIHQSSDLVDKVDTFFNFNNGGGEFGSWAFNLNPDQGENDPGLWISEPNGVDSGLVAAPVMNNGGNDSTSNSDSQPISKLCNGSSVENPNPKVLKSCEMVNFKNGIENGQEEDSSNKKRSPVSNNEEGMLSFTSVLPCDSNHSDLEASVAKEAESNRVVVEPEKKPRKRGRKPANGREEPLNHVEAERQRREKLNQRFYSLRAVVPNVSKMDKASLLGDAISYISELKSKLQKAESDKEELQKQIDVMNKEAGNAKSSVKDRKCLNQESSVLIEMEVDVKIIGWDAMIRIQCSKRNHPGAKFMEALKELDLEVNHASLSVVNDLMIQQATVKMGNQFFTQDQLKVALTEKVGECP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
449	Phosphorylation	VSKMDKASLLGDAIS CCCCCHHHHHHHHHH		28295753
456	Phosphorylation	SLLGDAISYISELKS HHHHHHHHHHHHHHH		28295753
459	Phosphorylation	GDAISYISELKSKLQ HHHHHHHHHHHHHHH		28295753

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MYC4_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MYC4_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MYC4_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TI10B_ARATH	TIFY10B	physical	21335373
TIF3A_ARATH	JAZ11	physical	21335373
TIF3B_ARATH	JAZ12	physical	21335373
MYC4_ARATH	AT4G17880	physical	21335373
MYC3_ARATH	AT5G46760	physical	21335373
MYC2_ARATH	MYC2	physical	21335373
MED25_ARATH	PFT1	physical	22822211
MYB21_ARATH	MYB21	physical	26002869
MYB24_ARATH	MYB24	physical	26002869

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.