| UniProt ID | MYC2_ARATH | |
|---|---|---|
| UniProt AC | Q39204 | |
| Protein Name | Transcription factor MYC2 | |
| Gene Name | MYC2 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 623 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Transcriptional activator. Common transcription factor of light, abscisic acid (ABA), and jasmonic acid (JA) signaling pathways. With MYC3 and MYC4, controls additively subsets of JA-dependent responses. In cooperation with MYB2 is involved in the regulation of ABA-inducible genes under drought stress conditions. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the MYC recognition site (5'-CACATG-3'), and to the G-box (5'-CACNTG-3') and Z-box (5'-ATACGTGT-3') of promoters. Binds directly to the promoters of the transcription factors PLETHORA1 (PLT1) and PLT2 and represses their expression. Negative regulator of blue light-mediated photomorphogenic growth and blue- and far-red-light regulated gene expression. Activates multiple TIFY/JAZ promoters. Positive regulator of lateral root formation. Regulates sesquiterpene biosynthesis. Subjected to proteasome-dependent proteolysis. The presence of the destruction element (DE) involved in turnover is required for the function to regulate gene transcription.. | |
| Protein Sequence | MTDYRLQPTMNLWTTDDNASMMEAFMSSSDISTLWPPASTTTTTATTETTPTPAMEIPAQAGFNQETLQQRLQALIEGTHEGWTYAIFWQPSYDFSGASVLGWGDGYYKGEEDKANPRRRSSSPPFSTPADQEYRKKVLRELNSLISGGVAPSDDAVDEEVTDTEWFFLVSMTQSFACGAGLAGKAFATGNAVWVSGSDQLSGSGCERAKQGGVFGMHTIACIPSANGVVEVGSTEPIRQSSDLINKVRILFNFDGGAGDLSGLNWNLDPDQGENDPSMWINDPIGTPGSNEPGNGAPSSSSQLFSKSIQFENGSSSTITENPNLDPTPSPVHSQTQNPKFNNTFSRELNFSTSSSTLVKPRSGEILNFGDEGKRSSGNPDPSSYSGQTQFENKRKRSMVLNEDKVLSFGDKTAGESDHSDLEASVVKEVAVEKRPKKRGRKPANGREEPLNHVEAERQRREKLNQRFYALRAVVPNVSKMDKASLLGDAIAYINELKSKVVKTESEKLQIKNQLEEVKLELAGRKASASGGDMSSSCSSIKPVGMEIEVKIIGWDAMIRVESSKRNHPAARLMSALMDLELEVNHASMSVVNDLMIQQATVKMGFRIYTQEQLRASLISKIG | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 123 | Phosphorylation | NPRRRSSSPPFSTPA CCCCCCCCCCCCCCC | 23111157 | ||
| 328 | Phosphorylation | ENPNLDPTPSPVHSQ CCCCCCCCCCCCCCC | 23593022 | ||
| 363 | Phosphorylation | STLVKPRSGEILNFG CCEECCCCCCCCCCC | 30291188 | ||
| 413 | Phosphorylation | VLSFGDKTAGESDHS EECCCCCCCCCCCCH | 23776212 | ||
| 417 | Phosphorylation | GDKTAGESDHSDLEA CCCCCCCCCCHHHHH | 23776212 | ||
| 420 | Phosphorylation | TAGESDHSDLEASVV CCCCCCCHHHHHHHH | 23776212 | ||
| 425 | Phosphorylation | DHSDLEASVVKEVAV CCHHHHHHHHHHHHH | 23776212 | ||
| 563 | Phosphorylation | DAMIRVESSKRNHPA EEEEEHHHHCCCCHH | 23593022 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
| 563 | S | Phosphorylation | Kinase | KIN10 | Q38997 | Uniprot |
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MYC2_ARATH !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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