GAI_ARATH - dbPTM
GAI_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID GAI_ARATH
UniProt AC Q9LQT8
Protein Name DELLA protein GAI
Gene Name GAI
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 533
Subcellular Localization Nucleus .
Protein Description Probable transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. No effect of the BOI proteins on its stability. Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes. Positively regulates XERICO expression. In contrast to RGA, it is less sensitive to GA. Its activity is probably regulated by other phytohormones such as auxin and ethylene..
Protein Sequence MKRDHHHHHHQDKKTMMMNEEDDGNGMDELLAVLGYKVRSSEMADVAQKLEQLEVMMSNVQEDDLSQLATETVHYNPAELYTWLDSMLTDLNPPSSNAEYDLKAIPGDAILNQFAIDSASSSNQGGGGDTYTTNKRLKCSNGVVETTTATAESTRHVVLVDSQENGVRLVHALLACAEAVQKENLTVAEALVKQIGFLAVSQIGAMRKVATYFAEALARRIYRLSPSQSPIDHSLSDTLQMHFYETCPYLKFAHFTANQAILEAFQGKKRVHVIDFSMSQGLQWPALMQALALRPGGPPVFRLTGIGPPAPDNFDYLHEVGCKLAHLAEAIHVEFEYRGFVANTLADLDASMLELRPSEIESVAVNSVFELHKLLGRPGAIDKVLGVVNQIKPEIFTVVEQESNHNSPIFLDRFTESLHYYSTLFDSLEGVPSGQDKVMSEVYLGKQICNVVACDGPDRVERHETLSQWRNRFGSAGFAAAHIGSNAFKQASMLLALFNGGEGYRVEESDGCLMLGWHTRPLIATSAWKLSTN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
15PhosphorylationHHHQDKKTMMMNEED
CCCCCCCCEECCCCC
18.9527545962
36PhosphorylationELLAVLGYKVRSSEM
HHHHHHCCCCCHHHH
11.3627545962

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
-KUbiquitinationE3 ubiquitin ligaseGID2Q9STX3
PMID:22199232

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of GAI_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of GAI_ARATH !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RBS2B_ARATHAT5G38420physical
21798944
MPK18_ARATHMPK18physical
21798944
WRK36_ARATHWRKY36physical
21798944
PSA7A_ARATHPAD1physical
21798944
FRL1A_ARATHFRL1physical
21798944
TIF7_ARATHTIFY7physical
21798944
SIGF_ARATHSIGFphysical
21798944
SUMO1_ARATHSUMO1physical
24434138
ZFP8_ARATHZFP8physical
25118255
TCP1_ARATHTCP1physical
25118255
ARR14_ARATHRR14physical
25118255
RAP23_ARATHEBPphysical
25118255
EIL2_ARATHEIL2physical
25118255
ABR1_ARATHABR1physical
25118255
TOE2_ARATHTOE2physical
25118255
TCP2_ARATHTCP2physical
25118255
TCP3_ARATHTCP3physical
25118255
TCP5_ARATHTCP5physical
25118255
TCP10_ARATHTCP10physical
25118255
TCP23_ARATHAT1G35560physical
25118255
BH143_ARATHAT5G09460physical
25118255
TCP15_ARATHAT1G69690physical
25118255
SPL5_ARATHSPL5physical
25118255
WOX9_ARATHHB-3physical
25118255
TCP8_ARATHAT1G58100physical
25118255
TCP13_ARATHPTF1physical
25118255
NAC98_ARATHCUC2physical
25118255
RAP27_ARATHRAP2.7physical
25118255
BH130_ARATHAT2G42280physical
25118255
ESR1_ARATHESR1physical
25118255
TCP16_ARATHTCP16physical
25118255
AGL86_ARATHAGL86physical
25118255
BH089_ARATHAT1G06170physical
25118255
BH091_ARATHAT2G31210physical
25118255
UNE10_ARATHUNE10physical
25118255
PIF3_ARATHPIF3physical
25118255
BBX25_ARATHSTHphysical
25118255
HAT1_ARATHHAT1physical
25118255
PIF4_ARATHPIF4physical
25118255
DRE2F_ARATHAT3G57600physical
25118255
TGA4_ARATHTGA4physical
25118255
PHL1_ARATHAT5G29000physical
25118255
ERF17_ARATHAT1G19210physical
25118255
SPL6_ARATHAT1G69170physical
25118255
ERF39_ARATHAT4G16750physical
25118255
TCP14_ARATHTCP14physical
25118255
NAC42_ARATHNAC042physical
25118255
CXIP4_ARATHCXIP4physical
25118255
BH018_ARATHAT2G22750physical
25118255
TCP19_ARATHAT5G51910physical
25118255
BH011_ARATHbHLH11physical
25118255
BH087_ARATHAT3G21330physical
25118255
DOF43_ARATHAT4G21040physical
25118255
BH049_ARATHAT1G68920physical
25118255
TI10A_ARATHJAZ1physical
21145503
GL1_ARATHMYB0physical
24659329
EGL1_ARATHEGL3physical
24659329
GL3_ARATHGL3physical
24659329
BBX24_ARATHSTOphysical
25656233
PFD3_ARATHPFD3physical
23583555
PFD5_ARATHPFD5physical
23583555
ATML1_ARATHATML1physical
24989044
PDF2_ARATHPDF2physical
24989044

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of GAI_ARATH

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Related Literatures of Post-Translational Modification

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