TCP10_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TCP10_ARATH
• UniProt AC: O82277
• Protein Name: Transcription factor TCP10
• Gene Name: TCP10
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 361
• Subcellular Localization: Nucleus .
• Protein Description: Plays a pivotal role in the control of morphogenesis of shoot organs by negatively regulating the expression of boundary-specific genes such as CUC genes, probably through the induction of miRNA (e.g. miR164). Participates in ovule develpment. [PubMed: 25378179]
• Protein Sequence: MGLKGYSVGEGGGEIVEVQGGHIIRATGRKDRHSKVFTSKGPRDRRVRLSAHTAIQFYDVQDRLGYDRPSKAVDWLIKKAKTAIDKLELGETTTTTTRQEPVNTKPESPTLVFQRENNDQTQFVAANLDPEDAMKTFFPATTTTNGGGGTNINFQNYPHQDDNNMVSRTTTPPPNLSQDLGLSLHPFQGNNNTVVVPETNNFTTTHFDTFGRISGWNHHDLTMTSSSSSEHQQQEQEERSNGGFMVNHHPHHHHHQPSMMTLLNSQQQQVFLGGQQQQQQRGTLQSSLFPHSFRSWDHHQTTSDHHHHQNQASSMFASSSQYGSHGMMMMQGLSFPNTTRLLHGEEATQPNSSSSPPNSHL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
104	Phosphorylation	TRQEPVNTKPESPTL CCCCCCCCCCCCCEE	48.48	23776212
108	Phosphorylation	PVNTKPESPTLVFQR CCCCCCCCCEEEEEC	31.54	23776212
110	Phosphorylation	NTKPESPTLVFQREN CCCCCCCEEEEECCC	44.85	23776212
353	Phosphorylation	EATQPNSSSSPPNSH CCCCCCCCCCCCCCC	41.28	23111157
354	Phosphorylation	ATQPNSSSSPPNSHL CCCCCCCCCCCCCCC	46.84	23111157
355	Phosphorylation	TQPNSSSSPPNSHL- CCCCCCCCCCCCCC-	46.45	23111157
359	Phosphorylation	SSSSPPNSHL----- CCCCCCCCCC-----	31.75	27545962

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TCP10_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TCP10_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TCP10_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
LBD6_ARATH	AS2	physical	22380849
TCP4_ARATH	TCP4	physical	24129704
TCP3_ARATH	TCP3	physical	24129704
TCP2_ARATH	TCP2	physical	24129704
TCP24_ARATH	TCP24	physical	24129704
TCP13_ARATH	PTF1	physical	24129704
TCP17_ARATH	TCP17	physical	24129704
TCP5_ARATH	TCP5	physical	24129704
TCP11_ARATH	AT2G37000	physical	24129704
TCP19_ARATH	AT5G51910	physical	24129704
TCP21_ARATH	AT5G08330	physical	24129704
TCP15_ARATH	AT1G69690	physical	24129704
TCP20_ARATH	TCP20	physical	24129704
TCP23_ARATH	AT1G35560	physical	24129704
TCP8_ARATH	AT1G58100	physical	24129704
TCP14_ARATH	TCP14	physical	24129704

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks.";
Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.;
Plant Physiol. 150:889-903(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-108, AND MASSSPECTROMETRY.
PubMed: 19376835