UniProt ID | MPK18_ARATH | |
---|---|---|
UniProt AC | Q9C5C0 | |
Protein Name | Mitogen-activated protein kinase 18 | |
Gene Name | MPK18 | |
Organism | Arabidopsis thaliana (Mouse-ear cress). | |
Sequence Length | 615 | |
Subcellular Localization | Cytoplasm . | |
Protein Description | Mitogen-activated protein kinase (MAPK) that is specifically regulated by PHS1 and mediates signaling that regulates cortical microtubule functions, maybe through regulation of microtubule dynamic instability.. | |
Protein Sequence | MQQNQVKKGTKEMEFFTEYGDANRYRILEVIGKGSYGVVCAAIDTHTGEKVAIKKINDVFEHISDALRILREVKLLRLLRHPDIVEIKSIMLPPSKREFKDIYVVFELMESDLHQVIKANDDLTREHHQFFLYQMLRALKFMHTANVYHRDLKPKNILANANCKLKVCDFGLARVAFNDTPTTVFWTDYVATRWYRAPELCGSFFSKYTPAIDVWSIGCIFAEVLTGKPLFPGKSVVHQLELITDLLGTPKSETISGVRNDKARKYLTEMRKKNPVTFSQKFSKADPLALRLLQRLLAFDPKDRPTPAEALADPYFKGLSKIEREPSSQQISKMEFEFERRRLTKDDIRELIYREILEYHPQLLKDYMSGSEGSNFVYPSAIGHLRQQFTYLEENSSRNGPVIPLERKHASLPRSTVHSTVVHSTSQPNLGATDSRRVSFEPSKNGASSAGHPSTSAYPTKSIGPPPRVPPSGRPGRVVESSVSYENGRNLKEAYFRSAVSSPHCYFRPNTMTNPENRNIEASSFPPKPQNPVHQFSPTEPPAATTNQADVETMNHPNPYFQPQLPKTDQLNNNTHMAIDAKLLQAQSQFGPAGAAAVAVAAHRNIGTISYSAAS | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
180 | Phosphorylation | ARVAFNDTPTTVFWT EEEECCCCCCCEEEE | 24.52 | 30407730 | |
182 | Phosphorylation | VAFNDTPTTVFWTDY EECCCCCCCEEEEHH | 37.37 | 30407730 | |
183 | Phosphorylation | AFNDTPTTVFWTDYV ECCCCCCCEEEEHHC | 18.21 | 30407730 | |
187 | Phosphorylation | TPTTVFWTDYVATRW CCCCEEEEHHCCCCC | 13.14 | 23111157 | |
189 | Phosphorylation | TTVFWTDYVATRWYR CCEEEEHHCCCCCCC | 5.66 | 23111157 | |
192 | Phosphorylation | FWTDYVATRWYRAPE EEEHHCCCCCCCCHH | 16.22 | 30407730 | |
411 | Phosphorylation | PLERKHASLPRSTVH CCCHHCCCCCCCEEE | 38.33 | 29654922 | |
425 | Phosphorylation | HSTVVHSTSQPNLGA EEEEEECCCCCCCCC | 19.26 | 25561503 | |
426 | Phosphorylation | STVVHSTSQPNLGAT EEEEECCCCCCCCCC | 46.81 | 25561503 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MPK18_ARATH !! |
Modified Location | Modified Residue | Modification | Function | Reference |
---|---|---|---|---|
187 | T | Phosphorylation |
| 28848569 |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MPK18_ARATH !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
CLAH2_ARATH | AT3G08530 | physical | 21798944 | |
PUB14_ARATH | PUB14 | physical | 21798944 | |
2AB2A_ARATH | AT5G44090 | physical | 21798944 | |
RGA_ARATH | RGA1 | physical | 21798944 | |
MPK18_ARATH | MPK18 | physical | 19392697 |
Kegg Drug | ||||||
---|---|---|---|---|---|---|
DrugBank | ||||||
There are no disease associations of PTM sites. |
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