| UniProt ID | MTP1_ARATH | |
|---|---|---|
| UniProt AC | Q9ZT63 | |
| Protein Name | Metal tolerance protein 1 | |
| Gene Name | MTP1 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 398 | |
| Subcellular Localization |
Vacuole membrane Multi-pass membrane protein . Tonoplast. |
|
| Protein Description | Mediates zinc accumulation in roots and confers resistance to zinc. Involved in sequestration of excess zinc in the cytoplasm into vacuoles to maintain zinc homeostasis. Can also transport cadmium with a low efficiency.. | |
| Protein Sequence | MESSSPHHSHIVEVNVGKSDEERIIVASKVCGEAPCGFSDSKNASGDAHERSASMRKLCIAVVLCLVFMSVEVVGGIKANSLAILTDAAHLLSDVAAFAISLFSLWAAGWEATPRQTYGFFRIEILGALVSIQLIWLLTGILVYEAIIRIVTETSEVNGFLMFLVAAFGLVVNIIMAVLLGHDHGHSHGHGHGHGHDHHNHSHGVTVTTHHHHHDHEHGHSHGHGEDKHHAHGDVTEQLLDKSKTQVAAKEKRKRNINLQGAYLHVLGDSIQSVGVMIGGAIIWYNPEWKIVDLICTLAFSVIVLGTTINMIRNILEVLMESTPREIDATKLEKGLLEMEEVVAVHELHIWAITVGKVLLACHVNIRPEADADMVLNKVIDYIRREYNISHVTIQIER | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Phosphorylation | -----MESSSPHHSH -----CCCCCCCCCC | 34.51 | 27643528 | |
| 4 | Phosphorylation | ----MESSSPHHSHI ----CCCCCCCCCCE | 34.28 | 27643528 | |
| 5 | Phosphorylation | ---MESSSPHHSHIV ---CCCCCCCCCCEE | 37.22 | 27643528 | |
| 9 | Phosphorylation | ESSSPHHSHIVEVNV CCCCCCCCCEEEEEC | 16.33 | 27643528 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MTP1_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MTP1_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MTP1_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| AB12A_ARATH | ATH16 | physical | 24833385 | |
| CNIH1_ARATH | AT3G12180 | physical | 24833385 | |
| PAM74_ARATH | AT5G59650 | physical | 24833385 | |
| BETL2_ARATH | AT1G29060 | physical | 24833385 | |
| VAP21_ARATH | AT5G47180 | physical | 24833385 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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