AB12A_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AB12A_ARATH
• UniProt AC: Q9FLT8
• Protein Name: ABC transporter A family member 12
• Gene Name: ABCA12
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 917
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: MVNPSPASFWTQANALLRKNLTYQRKHIWTNVRLILVPLFLCLILLAIQQVLDALMKGVSDMSNCGGNVTLPGGICPIPNPPSLPPMLQIPQHELRSVKTDFFSYKDLPDKLCRETGSCPVTILFTGDKLPLGKALSANIFSTSFVVNSSDLLPTLANNVLGSTEAAGEDNYEDPGIASDLPIYSIQPSCSANSTWPLSLGQIQTAVKCVQGLCLWRNNSVEVNDELFKGSWRGNPAGMPNEIVAAYDLMSTDRKNFNVTIWYNSTYNDEFATGQALKLVRVPRSINLISNAYLKFLKGPGTRILFEFLKEVPKEETKMNQDIASLLGPLFFTWVVLLLFPVILTSLVYEKQERLRIIMKMHGLGDGPYWMISYAYFLTISMLYVISLVGFGSAIGLKYFRRNDYSIQFVFYFIYSNLQISLAFLVSSIFSKVKTVTVIAYILVYGTGLLGSFLFQKMIETQSFPEEWILAMELYPGFSLYRGLYEFSQYASRGNGMKWQDLSDSGMGEVFCIMSVEWFLALIVAYYIDQVFTSGKHPFFFLVNLFKSPSSLPRRPTVQRLDSKRVFIDMDKHDVTQERESVQKLRNEGSTGHAILCDNLKKVYPGRDGNPPKMAVRGLYLSVSSGECFGMLGPNGAGKTSFISMMTGLLKPSSGTALVQGLDICKDMNKVYTSMGVCPQHDLLWETLTGREHLLFYGRLKNIKGSDLTQAVEESLKSVSLYDGGVGDKPAGNYSGGMKRRLSVAISLIGNPKVVYLDEPSTGLDPASRKNLWNVIKRAKQNTAIILTTHSMEEAEFLCDRLGIFVDGGLQCIGNSKELKSRYGGSYVFTMTTSSKHEEEVERLVESVSPNAKKIYHLAGTQKFELPKQEVRIAEVFRAVEKAKANFTVFAWGLADTTLEDVFIKVARTAQAFISLS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
485	Phosphorylation	FSLYRGLYEFSQYAS CCHHHHHHHHHHHHH	20.11	19880383
488	Phosphorylation	YRGLYEFSQYASRGN HHHHHHHHHHHHCCC	15.44	19880383
490	Phosphorylation	GLYEFSQYASRGNGM HHHHHHHHHHCCCCC	12.83	19880383
548	Phosphorylation	FLVNLFKSPSSLPRR EEEEHHCCCCCCCCC	23.76	23776212
550	Phosphorylation	VNLFKSPSSLPRRPT EEHHCCCCCCCCCCC	52.15	23776212
551	Phosphorylation	NLFKSPSSLPRRPTV EHHCCCCCCCCCCCC	45.86	23776212
581	Phosphorylation	DVTQERESVQKLRNE CCHHHHHHHHHHHHC	35.75	19880383
734	Phosphorylation	GDKPAGNYSGGMKRR CCCCCCCCCCHHHHH	14.05	24894044

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AB12A_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AB12A_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AB12A_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CNIH1_ARATH	AT3G12180	physical	24833385

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.