dbPTM

M3K2_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	M3K2_ARATH
UniProt AC	Q9FZ36
Protein Name	Mitogen-activated protein kinase kinase kinase 2
Gene Name	ANP2
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	651
Subcellular Localization	Cytoplasm, cytoskeleton .
Protein Description	Involved in cortical microtubules organization and stabilization by regulating the phosphorylation state of microtubule-associated proteins such as MAP65-1..
Protein Sequence	MQDLFGSVRRSLVFRSTTDDENQENHPPPFPSLLADKITSCIRKSMVFAKSQSPPNNSTVQIKPPIRWRKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEEEVKLLKNLSHPNIVRYLGTVREDETLNILLEFVPGGSISSLLEKFGAFPESVVRTYTNQLLLGLEYLHNHAIMHRDIKGANILVDNQGCIKLADFGASKQVAELATISGAKSMKGTPYWMAPEVILQTGHSFSADIWSVGCTVIEMVTGKAPWSQQYKEIAAIFHIGTTKSHPPIPDNISSDANDFLLKCLQQEPNLRPTASELLKHPFVTGKQKESASKDLTSFMDNSCSPLPSELTNITSYQTSTSDDVGDICNLGSLTCTLAFPEKSIQNNSLCLKSNNGYDDDDDNDMCLIDDENFLTYNGETGPSLDNNTDAKKSCDTMSEISDILKCKFDENSGNGETETKVSMEVDHPSYSEDENELTESKIKAFLDDKAAELKKLQTPLYEEFYNGMITCSPICMESNINNNKREEAPRGFLKLPPKSRSPSQGHIGRSPSRATDAACCSKSPESGNSSGAPKNSNASAGAEQESNSQSVALSEIERKWKEELDQELERKRREITRQAGMGSSPRDRSLSRHREKSRFASPGK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
226	Phosphorylation	KQVAELATISGAKSM HHHHHHHHHCCCCCC	28.44	23776212
228	Phosphorylation	VAELATISGAKSMKG HHHHHHHCCCCCCCC	28.48	23776212
232	Phosphorylation	ATISGAKSMKGTPYW HHHCCCCCCCCCCCE	25.78	23776212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of M3K2_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of M3K2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of M3K2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of M3K2_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of M3K2_ARATH

Related Literatures of Post-Translational Modification