| UniProt ID | ETR1_ARATH | |
|---|---|---|
| UniProt AC | P49333 | |
| Protein Name | Ethylene receptor 1 {ECO:0000303|PubMed:8211181} | |
| Gene Name | ETR1 {ECO:0000303|PubMed:8211181} | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 738 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Multi-pass membrane protein . |
|
| Protein Description | Ethylene receptor related to bacterial two-component regulators. Acts as a redundant negative regulator of ethylene signaling. [PubMed: 15466228] | |
| Protein Sequence | MEVCNCIEPQWPADELLMKYQYISDFFIAIAYFSIPLELIYFVKKSAVFPYRWVLVQFGAFIVLCGATHLINLWTFTTHSRTVALVMTTAKVLTAVVSCATALMLVHIIPDLLSVKTRELFLKNKAAELDREMGLIRTQEETGRHVRMLTHEIRSTLDRHTILKTTLVELGRTLALEECALWMPTRTGLELQLSYTLRHQHPVEYTVPIQLPVINQVFGTSRAVKISPNSPVARLRPVSGKYMLGEVVAVRVPLLHLSNFQINDWPELSTKRYALMVLMLPSDSARQWHVHELELVEVVADQVAVALSHAAILEESMRARDLLMEQNVALDLARREAETAIRARNDFLAVMNHEMRTPMHAIIALSSLLQETELTPEQRLMVETILKSSNLLATLMNDVLDLSRLEDGSLQLELGTFNLHTLFREVLNLIKPIAVVKKLPITLNLAPDLPEFVVGDEKRLMQIILNIVGNAVKFSKQGSISVTALVTKSDTRAADFFVVPTGSHFYLRVKVKDSGAGINPQDIPKIFTKFAQTQSLATRSSGGSGLGLAISKRFVNLMEGNIWIESDGLGKGCTAIFDVKLGISERSNESKQSGIPKVPAIPRHSNFTGLKVLVMDENGVSRMVTKGLLVHLGCEVTTVSSNEECLRVVSHEHKVVFMDVCMPGVENYQIALRIHEKFTKQRHQRPLLVALSGNTDKSTKEKCMSFGLDGVLLKPVSLDNIRDVLSDLLEPRVLYEGM | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 239 | Phosphorylation | VARLRPVSGKYMLGE CCCCEECCCCCCCCE | 32.05 | 19880383 | |
| 353 | Phosphorylation | DFLAVMNHEMRTPMH HHHHHHCCCCCCHHH | 16.48 | 20591837 | |
| 659 | Phosphorylation | EHKVVFMDVCMPGVE CCEEEEEEEECCCCC | 20.99 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ETR1_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference |
|---|---|---|---|---|
| 353 | H | Phosphorylation |
| 20591837 |
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ETR1_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| CTR1_ARATH | CTR1 | physical | 12837948 | |
| CTR1_ARATH | CTR1 | physical | 12535337 | |
| AHP1_ARATH | AHP1 | physical | 10930573 | |
| AHP2_ARATH | AHP2 | physical | 10930573 | |
| CTR1_ARATH | CTR1 | physical | 12821658 | |
| CTR1_ARATH | CTR1 | physical | 9560288 | |
| CALR1_ARATH | CRT1a | physical | 16415218 | |
| CTR1_ARATH | CTR1 | physical | 24006427 | |
| THOC1_ARATH | THO1 | genetic | 25680185 | |
| HHP2_ARATH | HHP2 | physical | 24833385 | |
| HHP4_ARATH | HHP4 | physical | 24833385 | |
| UBC32_ARATH | UBC32 | physical | 24833385 | |
| UBC34_ARATH | UBC34 | physical | 24833385 | |
| ACBP6_ARATH | ACBP6 | physical | 24833385 | |
| CNIH1_ARATH | AT3G12180 | physical | 24833385 | |
| CP21D_ARATH | AT3G66654 | physical | 24833385 | |
| Y1680_ARATH | AT1G68400 | physical | 24833385 | |
| BET12_ARATH | ATBET12 | physical | 24833385 | |
| TBL18_ARATH | TBL18 | physical | 24833385 | |
| MMGT_ARATH | AT5G03345 | physical | 24833385 | |
| AHP1_ARATH | AHP1 | physical | 16965536 | |
| AHP2_ARATH | AHP2 | physical | 16965536 | |
| AHP3_ARATH | AHP3 | physical | 16965536 | |
| CYB5B_ARATH | CB5-B | genetic | 24635651 | |
| CYB5C_ARATH | CB5-C | genetic | 24635651 | |
| CYB5D_ARATH | CB5-D | genetic | 24635651 | |
| ERS1_ARATH | ERS1 | genetic | 25988998 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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