UFO1_YEAST - dbPTM
UFO1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID UFO1_YEAST
UniProt AC Q04511
Protein Name Ubiquitin ligase complex F-box protein UFO1
Gene Name UFO1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 668
Subcellular Localization
Protein Description Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins (By similarity)..
Protein Sequence MERPGLVLQDLPPEILINIFSHLDEKDLFTLQELSTHFRNLIHDEELWKNLFKSRVHTTHFPTFSQSSKFSVEYIERTRGLHHWQHNKAIRTKYTIIPTRNWDQPSIERIVFDYPRVAAYNDGTITILQLQNHKRQKKFKKLIYIPCTTPQGCSTMDFNINAAVFGRFDGRVFGKLLSNKSYLTPVMEFTGRHSAGVTAICNSESWDTSREDWSVSGSENGEIIWWCENKLVKMWKVSNRVIWKLAFFKDWTLIMDDEKLYIIHQMQELHSIDIPKDLDEQPMRVRFFKMDFGSMTLVLADLNNVYTISVNPNGNFGNLRKLEMPEQICAVEIDEKTSQREQNWQFAGDDGCYISLLTTQNTLYIINIRDLSSSGLKVQCKISFDEQVYVSQVTNLIVVVALPNVLQILNAMTGELIKTVLKTEKFPEFLKVSQDKIIMGSGNVLNYLKFVSSDSKKHHHSTKGKNTVSNKWNETLNTELQYYDEDEDLRRKRQSEISRLIDAYGGDLELSGDTDEENDIQLRIALLESQEAQARNQAEAGEPVGDDEDEQLRRALEESQLIYETQTNSSANHGNNTNDEIDEDDEEFLRAIRQSRVEDERRRHLRNHTTGRRNGPLSDDNFATYGAAESSERTSTENTIGSSVGVDASNNVDEDLQLAIALSLSEIN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
180UbiquitinationFGKLLSNKSYLTPVM
HHHHHCCCCCCCEEE		36.7823749301
436UbiquitinationFLKVSQDKIIMGSGN
HHHCCCCEEEECCCC		26.8824961812
465AcetylationHHHSTKGKNTVSNKW
CCCCCCCCCCCCHHH		51.5017397211
504PhosphorylationISRLIDAYGGDLELS
HHHHHHHHCCCCEEC		20.2122369663
511PhosphorylationYGGDLELSGDTDEEN
HCCCCEECCCCCCCC		25.8322369663
514PhosphorylationDLELSGDTDEENDIQ
CCEECCCCCCCCHHH		49.1622369663
570PhosphorylationYETQTNSSANHGNNT
EEECCCCCCCCCCCC		34.8521440633
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
-KUbiquitinationE3 ubiquitin ligaseUFO1Q04511
PMID:22199232
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of UFO1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of UFO1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SKP1_YEASTSKP1physical
11805837
CDC53_YEASTCDC53physical
11805837
SKP1_YEASTSKP1physical
10688190
SKP1_YEASTSKP1physical
14506225
CDC53_YEASTCDC53physical
14506225
DDI1_YEASTDDI1physical
16478980
FAS2_YEASTFAS2physical
18949821
RPB1_YEASTRPO21physical
18949821
RPB2_YEASTRPB2physical
18949821
SPT5_YEASTSPT5physical
18949821
HSP71_YEASTSSA1physical
18949821
HSP72_YEASTSSA2physical
18949821
GAL1_YEASTGAL1physical
18949821
GIP2_YEASTGIP2physical
18949821
RL4A_YEASTRPL4Aphysical
18949821
RPN1_YEASTRPN1physical
18949821
CDC53_YEASTCDC53physical
21389113
SKP1_YEASTSKP1physical
21389113
GAL80_YEASTGAL80genetic
22479149
UFO1_YEASTUFO1physical
22815701
CDC53_YEASTCDC53physical
22815701
HO_YEASTHOphysical
22815701
RPN11_YEASTRPN11physical
22815701
DDI1_YEASTDDI1physical
22815701
RPN1_YEASTRPN1physical
22815701
RPN12_YEASTRPN12physical
22815701
RBG1_YEASTRBG1physical
24389104
MTH1_YEASTMTH1physical
24389104
FAR1_YEASTFAR1physical
24389104
HO_YEASTHOphysical
24389104
UFO1_YEASTUFO1physical
14747994
CDC4_YEASTCDC4genetic
16478980
SKP1_YEASTSKP1genetic
16478980
CDC53_YEASTCDC53genetic
16478980
UBI4P_YEASTUBI4physical
25703377
YAJ9_YEASTYAR029Wgenetic
27708008
TEC1_YEASTTEC1genetic
27708008
AAD3_YEASTAAD3genetic
27708008
STP4_YEASTSTP4genetic
27708008
AROF_YEASTARO3genetic
27708008
PUF6_YEASTPUF6genetic
27708008
BLM10_YEASTBLM10genetic
27708008
MRM2_YEASTMRM2genetic
27708008
RL11B_YEASTRPL11Bgenetic
27708008
YAP3_YEASTYAP3genetic
27708008
RS27B_YEASTRPS27Bgenetic
27708008
BNR1_YEASTBNR1genetic
27708008
VPS53_YEASTVPS53genetic
27708008
IME2_YEASTIME2genetic
27708008
PIR5_YEASTYJL160Cgenetic
27708008
MNN11_YEASTMNN11genetic
27708008
YL040_YEASTAFB1genetic
27708008
GLYC_YEASTSHM2genetic
27708008
HRT3_YEASTHRT3genetic
27708008
SIW14_YEASTSIW14genetic
27708008
RL9B_YEASTRPL9Bgenetic
27708008
EOS1_YEASTEOS1genetic
27708008
RHO2_YEASTRHO2genetic
27708008
TOM70_YEASTTOM70genetic
27708008
YOL19_YEASTYOL019Wgenetic
27708008
YO075_YEASTYOL075Cgenetic
27708008
ADH1_YEASTADH1genetic
27708008
WSC3_YEASTWSC3genetic
27708008
AFI1_YEASTAFI1genetic
27708008
RDL1_YEASTRDL1genetic
27708008
ETFD_YEASTCIR2genetic
27708008
TGS1_YEASTTGS1genetic
27708008
MED8_YEASTMED8genetic
27708008
FAL1_YEASTFAL1genetic
27708008
CDC1_YEASTCDC1genetic
27708008
YJ9I_YEASTYJR141Wgenetic
27708008
ABF1_YEASTABF1genetic
27708008
PRS7_YEASTRPT1genetic
27708008
RU1C_YEASTYHC1genetic
27708008
ARP7_YEASTARP7genetic
27708008
MDM10_YEASTMDM10genetic
27708008
ERV46_YEASTERV46genetic
27708008
FMT_YEASTFMT1genetic
27708008
YPK3_YEASTYPK3genetic
27708008
YRO2_YEASTYRO2genetic
27708008
BMT2_YEASTBMT2genetic
27708008
MCFS2_YEASTEHT1genetic
27708008
PCH2_YEASTPCH2genetic
27708008
IDHP_YEASTIDP1genetic
27708008
RLA1_YEASTRPP1Agenetic
27708008
YD144_YEASTYDL144Cgenetic
27708008
ATIF_YEASTINH1genetic
27708008
AVT6_YEASTAVT6genetic
27708008
CSK2B_YEASTCKB1genetic
27708008
KXD1_YEASTKXD1genetic
27708008
NMA2_YEASTNMA2genetic
27708008
YG2G_YEASTYGR079Wgenetic
27708008
RL24B_YEASTRPL24Bgenetic
27708008
NPR3_YEASTNPR3genetic
27708008
SODM_YEASTSOD2genetic
27708008
YHT1_YEASTYHR131Cgenetic
27708008
STB5_YEASTSTB5genetic
27708008
PRM2_YEASTPRM2genetic
27708008
DPH1_YEASTDPH1genetic
27708008
YIS7_YEASTYIR007Wgenetic
27708008
DAL81_YEASTDAL81genetic
27708008
SDHX_YEASTYJL045Wgenetic
27708008
CHS6_YEASTCHS6genetic
27708008
YAK1_YEASTYAK1genetic
27708008
DAS1_YEASTDAS1genetic
27708008
YJS1_YEASTYJL181Wgenetic
27708008
PHO90_YEASTPHO90genetic
27708008
SFK1_YEASTSFK1genetic
27708008
SA190_YEASTSAP190genetic
27708008
DAL80_YEASTDAL80genetic
27708008
PTR2_YEASTPTR2genetic
27708008
DNM1_YEASTDNM1genetic
27708008
KIN2_YEASTKIN2genetic
27708008
NAH1_YEASTNHA1genetic
27708008
CRR1_YEASTCRR1genetic
27708008
MCP2_YEASTMCP2genetic
27708008
ATG39_YEASTYLR312Cgenetic
27708008
ARPC3_YEASTARC18genetic
27708008
RS29A_YEASTRPS29Agenetic
27708008
CCW14_YEASTCCW14genetic
27708008
RL6B_YEASTRPL6Bgenetic
27708008
IMP2_YEASTIMP2genetic
27708008
AIP1_YEASTAIP1genetic
27708008
GCSP_YEASTGCV2genetic
27708008
YHM2_YEASTYHM2genetic
27708008
GOT1_YEASTGOT1genetic
27708008
TOM7_YEASTTOM7genetic
27708008
RS7B_YEASTRPS7Bgenetic
27708008
YNK8_YEASTYNL108Cgenetic
27708008
ADE_YEASTAAH1genetic
27708008
PHO91_YEASTPHO91genetic
27708008
HAL9_YEASTHAL9genetic
27708008
HMI1_YEASTHMI1genetic
27708008
ZEO1_YEASTZEO1genetic
27708008
SIZ2_YEASTNFI1genetic
27708008
KIN4_YEASTKIN4genetic
27708008
SCP1_YEASTSCP1genetic
27708008
SVL3_YEASTSVL3genetic
27708008
ELOC_YEASTELC1genetic
27708008
GGPPS_YEASTBTS1genetic
27708008
RL21B_YEASTRPL21Bgenetic
27708008
GDE1_YEASTGDE1genetic
27708008
EAF3_YEASTEAF3genetic
27708008
YMC1_YEASTYMC1genetic
27708008
KAR3_YEASTKAR3genetic
27708008
ECM1_YEASTECM1genetic
29674565
RS6A_YEASTRPS6Bgenetic
29674565
RS6B_YEASTRPS6Bgenetic
29674565
PDC2_YEASTPDC2genetic
29674565
RRP8_YEASTRRP8genetic
29674565
SAC3_YEASTSAC3genetic
29674565
DBP3_YEASTDBP3genetic
29674565
TCD1_YEASTTCD1genetic
29674565
BTN1_YEASTYHC3genetic
29674565
ASF1_YEASTASF1genetic
29674565
CYP7_YEASTCPR7genetic
29674565
LAC1_YEASTLAC1genetic
29674565
ELM1_YEASTELM1genetic
29674565
PGM1_YEASTPGM1genetic
29674565
HBS1_YEASTHBS1genetic
29674565
FMP25_YEASTFMP25genetic
29674565
SSO2_YEASTSSO2genetic
29674565
ODP2_YEASTLAT1genetic
29674565
DYR_YEASTDFR1genetic
29674565
SCP1_YEASTSCP1genetic
29674565
ARL3_YEASTARL3genetic
29674565
ELP4_YEASTELP4genetic
29674565
NEW1_YEASTNEW1genetic
29674565
CGS5_YEASTCLB5genetic
29674565
HDA3_YEASTHDA3genetic
29674565
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of UFO1_YEAST

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-514, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory