| UniProt ID | PRP4_SCHPO | |
|---|---|---|
| UniProt AC | Q07538 | |
| Protein Name | Serine/threonine-protein kinase prp4 | |
| Gene Name | prp4 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 477 | |
| Subcellular Localization | ||
| Protein Description | Has a role in pre-mRNA splicing and is essential for growth. Phosphorylates srp1.. | |
| Protein Sequence | MSDDRFAEDEIIQQRRKRRLEILKKYQQTGNGHSDLSIPEKKLKEDVDQVSTTKPIEAVPKMKTNASKIEINKEGSNSNTKLDVTNSTTSDSPSIKSSVQIEDTEDDMFADSPSPSVKRQNTGKGISTLTRSFADMQDNWDDIEGYYKVVLMEELDSRYIVQSNLGKGMFSTVVSALDRNRNQTFAIKIIRNNEVMYKEGLKEVSILERLQAADREGKQHIIHYERHFMHKNHLCMVFEMLSLNLRDILKKFGRNVGLSIKAVRLYAYQMFMALDLLKQCNVIHSDIKPDNMLVNEKRNILKICDLGSASDASENEITPYLVSRFYRAPEIILGFPYSCPIDTWSVGCSLYELYTGQILFPGRTNNQMLRYMMECKGKFSHKMLKRSQFLNDHFDADFNFIQIDHDPITNQETRKPVKFSKPTKDIRSRLKEVPTSTDEEFIIRQELMDLLEKCLELNPEKRVPPEVALKHPFFIKK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 76 | Phosphorylation | IEINKEGSNSNTKLD EEECCCCCCCCCEEE | 37.87 | 25720772 | |
| 78 | Phosphorylation | INKEGSNSNTKLDVT ECCCCCCCCCEEEEE | 47.80 | 25720772 | |
| 89 | Phosphorylation | LDVTNSTTSDSPSIK EEEEECCCCCCCCCC | 30.29 | 24763107 | |
| 90 | Phosphorylation | DVTNSTTSDSPSIKS EEEECCCCCCCCCCC | 35.86 | 29996109 | |
| 92 | Phosphorylation | TNSTTSDSPSIKSSV EECCCCCCCCCCCCE | 21.95 | 28889911 | |
| 94 | Phosphorylation | STTSDSPSIKSSVQI CCCCCCCCCCCCEEE | 46.75 | 28889911 | |
| 104 | Phosphorylation | SSVQIEDTEDDMFAD CCEEEEECCCCCCCC | 28.64 | 25720772 | |
| 112 | Phosphorylation | EDDMFADSPSPSVKR CCCCCCCCCCCCCCC | 24.69 | 25720772 | |
| 114 | Phosphorylation | DMFADSPSPSVKRQN CCCCCCCCCCCCCCC | 33.49 | 25720772 | |
| 116 | Phosphorylation | FADSPSPSVKRQNTG CCCCCCCCCCCCCCC | 44.61 | 25720772 | |
| 318 | Phosphorylation | DASENEITPYLVSRF CCCCCCCHHHHHHHH | 10.33 | 29996109 | |
| 320 | Phosphorylation | SENEITPYLVSRFYR CCCCCHHHHHHHHCC | 15.87 | 28889911 | |
| 323 | Phosphorylation | EITPYLVSRFYRAPE CCHHHHHHHHCCCCC | 17.68 | 28889911 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PRP4_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PRP4_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PRP4_SCHPO !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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