SSR3_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SSR3_SCHPO
• UniProt AC: Q9P7S3
• Protein Name: SWI/SNF and RSC complexes subunit ssr3
• Gene Name: ssr3
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 425
• Subcellular Localization: Cytoplasm . Nucleus .
• Protein Description: Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particularly membrane and organelle development genes. Part of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors..
• Protein Sequence: MSNNSRLPENGVQSGNGEDAELKKSMRIIEREIPDSLLEKIPEAEDYIALQDLERKLDSLIVRKRFDLQDSLSRNSHKTRILRMYIHSTVANQSWQQKGENQENNSGDINSLPIPEWTLHIEGRLLVNPDDEDDKAFELAPFTNFFRKIAIQILRSDDLYPSGNYVEWNKLPDNSNTSNGITVTRKGDQSVDVKIMLYPEEHPERYKLSKAFANILGIREGTRPDIVSYLWQYIKFHRLQDMEEKRLINCDKALRDLFEADRLYFPRIPELMNRFLEPIDPIVIPYTINVSEHTVEKVTIFDIRINTEDPRHSQIRSFLATMMSQDKIRSIDDKLTELIQAITYSQSKYDFMKKFSESPIEFINEWIESQSRDLEIVLDGTNMNYAEKRSADYYQQPWVHESAFHYLNLLNSKKQQSVLNASAKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSNNSRLPE ------CCCCCCCCC	44.72	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SSR3_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SSR3_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SSR3_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MUG58_SCHPO	mug58	genetic	18818364
HIR1_SCHPO	hip1	genetic	18818364
HPC2_SCHPO	hip4	genetic	18818364
CID12_SCHPO	cid12	genetic	18818364
HRP3_SCHPO	hrp3	genetic	18818364
EXO1_SCHPO	exo1	genetic	18818364
VPS71_SCHPO	vps71	genetic	18818364

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.