PIT1_SCHPO - dbPTM
PIT1_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PIT1_SCHPO
UniProt AC O14132
Protein Name Sporulation protein kinase pit1
Gene Name pit1
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 650
Subcellular Localization
Protein Description Protein kinase which is essential for spore formation..
Protein Sequence MKKYLWGTPTTNTVFTGKQPKYTKEVRKCISIDEVYNVVRKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVSDATRLREVHSLLRLSENENIVNIFDLYIDQFRCLHIVMEFLDCNLYQLISTRKNDPLTLEQVQDIMRQIFKGLNHIHTNGFFHRDMKPENILISSNSDSSSFNVKIADFGLAREINSRPPYTEYVSTRWYRAPELLLRDSYYSFPVDIYAAGCMAFEIATLQPIFPGNDDFDQLYKMCEILGSPDEQSQNTGDKGGGIWDRAELLANKLGISLPKMAPLDFGDLFSPPWNLAFASMLSQLLKWDPAKRPTAEMCLDLEFCRVSAPADAVASKEEVNKNTDFRVSISYFPSSSSIPDECNTEEESRINPSTSKFLKQLNKGFNGFTKPFRKSRKQSKNRKNKSSVATQFSEESEDIADSITSSTFFPVLPQIRPSTPLNLKLRNFIISSSEDSTSPKAKEFDRPLPSTEFLVAINKSQEALLNNSPNSKSGSTQLSASTCLSDLISPQLSILSHEDKRENQSVNSESSKYSPRSSNHSPTLHSKDLHRDMATVNNYAKSPPSFHATQDLLRKTLAYTNSSGTSTVLSNDSSAISSTFLDRDFPDFGITSLAGSLTLPDSKIIDRSKTHVSTQLLP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
59PhosphorylationLATTKTPSKEVVAIK
EEECCCCCHHHEEHH		46.8329996109
193PhosphorylationGLAREINSRPPYTEY
HHCHHHCCCCCCCHH		52.4029996109
197PhosphorylationEINSRPPYTEYVSTR
HHCCCCCCCHHCCCC		18.1925720772
198PhosphorylationINSRPPYTEYVSTRW
HCCCCCCCHHCCCCC		26.9825720772
200PhosphorylationSRPPYTEYVSTRWYR
CCCCCCHHCCCCCCC		7.6028889911
202PhosphorylationPPYTEYVSTRWYRAP
CCCCHHCCCCCCCCC		16.0229996109
203PhosphorylationPYTEYVSTRWYRAPE
CCCHHCCCCCCCCCH		18.3829996109
347PhosphorylationAPADAVASKEEVNKN
CCHHHCCCHHHHCCC		33.7228889911
366PhosphorylationVSISYFPSSSSIPDE
EEEEECCCCCCCCCC		32.7125720772
369PhosphorylationSYFPSSSSIPDECNT
EECCCCCCCCCCCCC		39.8427738172
376PhosphorylationSIPDECNTEEESRIN
CCCCCCCCHHHHCCC		57.3325720772
463PhosphorylationKLRNFIISSSEDSTS
EEEEEEECCCCCCCC		24.0121712547
464PhosphorylationLRNFIISSSEDSTSP
EEEEEECCCCCCCCC		27.6021712547
465PhosphorylationRNFIISSSEDSTSPK
EEEEECCCCCCCCCC		38.3425720772
468PhosphorylationIISSSEDSTSPKAKE
EECCCCCCCCCCHHH		27.0824763107
469PhosphorylationISSSEDSTSPKAKEF
ECCCCCCCCCCHHHC		62.4628889911
470PhosphorylationSSSEDSTSPKAKEFD
CCCCCCCCCCHHHCC		28.4921712547
492PhosphorylationFLVAINKSQEALLNN
EEEEEECCHHHHHCC		28.8524763107
500PhosphorylationQEALLNNSPNSKSGS
HHHHHCCCCCCCCCC		25.1224763107
503PhosphorylationLLNNSPNSKSGSTQL
HHCCCCCCCCCCCCC		31.4224763107
549PhosphorylationSSKYSPRSSNHSPTL
CCCCCCCCCCCCCCC		38.5921712547
550PhosphorylationSKYSPRSSNHSPTLH
CCCCCCCCCCCCCCC		39.5821712547
553PhosphorylationSPRSSNHSPTLHSKD
CCCCCCCCCCCCCHH		24.6721712547
558PhosphorylationNHSPTLHSKDLHRDM
CCCCCCCCHHHCCHH		30.8621712547
574PhosphorylationTVNNYAKSPPSFHAT
HHHHHCCCCCCHHHH		33.5921712547
577PhosphorylationNYAKSPPSFHATQDL
HHCCCCCCHHHHHHH		32.8028889911
581PhosphorylationSPPSFHATQDLLRKT
CCCCHHHHHHHHHHH		17.6621712547
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PIT1_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PIT1_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PIT1_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
YCRE_SCHPOtrs130genetic
22681890
YEC6_SCHPOpcf3genetic
22681890
PPK14_SCHPOppk14genetic
22681890
MYO51_SCHPOmyo51genetic
22681890
ATP10_SCHPOatp10genetic
22681890
ARP6_SCHPOarp6genetic
22681890
MAK3_SCHPOmak3genetic
22681890
CG121_SCHPOcgi121genetic
22681890
BUN62_SCHPObun62genetic
22681890
YIOB_SCHPOSPAP27G11.11cgenetic
22681890
RL43B_SCHPOrpl4302genetic
22681890
PFD3_SCHPOpac10genetic
22681890
SSN3_SCHPOsrb10genetic
22681890
AROG_SCHPOSPAP8A3.07cgenetic
22681890
DSK1_SCHPOdsk1genetic
22681890
HUS1_SCHPOhus1genetic
22681890
SET1_SCHPOset1genetic
22681890
PPK16_SCHPOppk16genetic
22681890
YA4C_SCHPOSPAC31A2.12genetic
22681890
TBA2_SCHPOatb2genetic
22681890
PRZ1_SCHPOprz1genetic
22681890
SSN2_SCHPOmed13genetic
22681890
RS4A_SCHPOrps401genetic
22681890
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PIT1_SCHPO

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-200 AND THR-469, ANDMASS SPECTROMETRY.

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