dbPTM

YFT6_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YFT6_SCHPO
UniProt AC	Q9UUG2
Protein Name	Uncharacterized leucine-rich repeat-containing protein C926.06c
Gene Name	SPAC926.06c
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	621
Subcellular Localization	Cytoplasm . Nucleus . Vacuole membrane .
Protein Description
Protein Sequence	MGSTVDGEKYIRNLASYIRSHEKRFARAPYRAPNHSIFSDRPVQLQLTVHHLYYLLTKFEELGVNTGPLNIRIENLHSETFPSDYTSFLNQSPKKNDFDDNMSLNSIVTMGSILSNVSSVWSIFSTAPSEASETRNKQRILAILRYIYSCFTKLPAISLVYNPKTPLISQYEEFPLDTAVPITVFKNLSSLEIRGYDIRSIFGWDFLSTTLKSLILHHCDLADLSEVLIKLVLDDAELYRFRSSRQTYPQQPNSQPCEQHPAHANLRRSVSLGSKDYLKSSHPPVHKTLSQSVLVLSKDGNASSSGGTENQSANSSSSLMEKDAILSSSSWSQLLYLRCSSCKLKSIPKNVFLSLQSLVSLDLSGNELTEIPYALGELPQLCSLNLASNKITGCRTFYHISLSHLQILVLSRNHLTSLSGLENVPSLEKLDIRDNSITDVVEFRRLVGNTNFEEAYLSLNPFTKTYSSYRITIFNYFREYPGSKDIMLDGRGPGMLEKMYLSEKASAPERVISLNPVNQKSHSPAIKSSSTLRKASKTRIVDLSAPNSAVFSKNASGGDTSSNVSLLNGSASEEIPQNTESGQVFRKKIEMLRQEAGPEWVDALMKESVVKHKFRNKDESV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
87	Phosphorylation	TFPSDYTSFLNQSPK CCCCHHHHHHHCCCC	22.85	25720772
92	Phosphorylation	YTSFLNQSPKKNDFD HHHHHHCCCCCCCCC	37.30	25720772
269	Phosphorylation	AHANLRRSVSLGSKD CHHHHHHHHCCCCHH	15.04	28889911
271	Phosphorylation	ANLRRSVSLGSKDYL HHHHHHHCCCCHHHH	28.41	28889911
274	Phosphorylation	RRSVSLGSKDYLKSS HHHHCCCCHHHHHCC	27.87	28889911
288	Phosphorylation	SHPPVHKTLSQSVLV CCCCCCCCCCCEEEE	19.43	24763107
290	Phosphorylation	PPVHKTLSQSVLVLS CCCCCCCCCEEEEEE	26.16	28889911
292	Phosphorylation	VHKTLSQSVLVLSKD CCCCCCCEEEEEECC	17.65	28889911
297	Phosphorylation	SQSVLVLSKDGNASS CCEEEEEECCCCCCC	22.63	28889911
304	Phosphorylation	SKDGNASSSGGTENQ ECCCCCCCCCCCCCC	30.50	25720772
315	Phosphorylation	TENQSANSSSSLMEK CCCCCCCCCCCHHHH	31.17	24763107
317	Phosphorylation	NQSANSSSSLMEKDA CCCCCCCCCHHHHHH	27.58	25720772
318	Phosphorylation	QSANSSSSLMEKDAI CCCCCCCCHHHHHHH	33.41	21712547
544	Phosphorylation	KTRIVDLSAPNSAVF CCEEEECCCCCCEEE	36.90	24763107
548	Phosphorylation	VDLSAPNSAVFSKNA EECCCCCCEEECCCC	25.42	24763107
560	Phosphorylation	KNASGGDTSSNVSLL CCCCCCCCCCCEEEC	37.01	21712547
565	Phosphorylation	GDTSSNVSLLNGSAS CCCCCCEEECCCCCC	31.24	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YFT6_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YFT6_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YFT6_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YFT6_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YFT6_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-269; SER-271; SER-274;SER-290 AND SER-292, AND MASS SPECTROMETRY.	18257517 [Abstract]