SRP1_SCHPO - dbPTM
SRP1_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SRP1_SCHPO
UniProt AC Q10193
Protein Name Pre-mRNA-splicing factor srp1
Gene Name srp1
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 275
Subcellular Localization Nucleus .
Protein Description Has a role in pre-mRNA splicing where it is involved in spliceosome assembly..
Protein Sequence MSRRSLRTLYVTGFRDGMRARELAYEFEPFGPLIRCDIPIPRTRTSRPFAFVEYEDSRDAEDAYYEVHGRRLERGGGVLRVEWAKQPPPSGPGSKRGGRRERGGRVHGDSGRLRSRSPSPHEARSRSPYNDERSDRRSMSPRYRSRSRSPDGRSRSPDYDRRSPKRNHRSPSPVSFAPQKSPVENETETNVDNGDTKISESNEKSGTEVEQQSAPNSNGNEEVNNLEPVGQNESKQEPPKEENSNVSQEQPEQAQPEVSAASEQPESNPTTTESQ
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
115PhosphorylationGDSGRLRSRSPSPHE
CCCCCCCCCCCCHHC		41.5228889911
117PhosphorylationSGRLRSRSPSPHEAR
CCCCCCCCCCHHCHH		30.8628889911
119PhosphorylationRLRSRSPSPHEARSR
CCCCCCCCHHCHHHC		39.8928889911
125PhosphorylationPSPHEARSRSPYNDE
CCHHCHHHCCCCCCC		44.1328889911
127PhosphorylationPHEARSRSPYNDERS
HHCHHHCCCCCCCCC		32.7428889911
129PhosphorylationEARSRSPYNDERSDR
CHHHCCCCCCCCCCC		36.1728889911
134PhosphorylationSPYNDERSDRRSMSP
CCCCCCCCCCCCCCH		33.1625720772
154PhosphorylationSRSPDGRSRSPDYDR
CCCCCCCCCCCCCCC		42.5128889911
156PhosphorylationSPDGRSRSPDYDRRS
CCCCCCCCCCCCCCC		24.3028889911
159PhosphorylationGRSRSPDYDRRSPKR
CCCCCCCCCCCCCCC		18.0928889911
163PhosphorylationSPDYDRRSPKRNHRS
CCCCCCCCCCCCCCC		35.3529996109
170PhosphorylationSPKRNHRSPSPVSFA
CCCCCCCCCCCCCCC		23.3728889911
172PhosphorylationKRNHRSPSPVSFAPQ
CCCCCCCCCCCCCCC		38.9028889911
175PhosphorylationHRSPSPVSFAPQKSP
CCCCCCCCCCCCCCC		21.0524763107
181PhosphorylationVSFAPQKSPVENETE
CCCCCCCCCCCCCCC		29.0028889911
187PhosphorylationKSPVENETETNVDNG
CCCCCCCCCCCCCCC		60.7429996109
189PhosphorylationPVENETETNVDNGDT
CCCCCCCCCCCCCCC		48.2221712547
196PhosphorylationTNVDNGDTKISESNE
CCCCCCCCEECCCCC		31.5127738172
205PhosphorylationISESNEKSGTEVEQQ
ECCCCCCCCCCCCCC		44.7827738172
213PhosphorylationGTEVEQQSAPNSNGN
CCCCCCCCCCCCCCC		45.4425720772
217PhosphorylationEQQSAPNSNGNEEVN
CCCCCCCCCCCHHHH		45.0925720772
270PhosphorylationEQPESNPTTTESQ--
CCCCCCCCCCCCC--		51.0727738172
274PhosphorylationSNPTTTESQ------
CCCCCCCCC------		38.8124763107
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SRP1_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SRP1_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SRP1_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SRP2_SCHPOsrp2physical
12186627
COX19_SCHPOSPCC1672.04cgenetic
22681890
ASL1_SCHPOasl1genetic
22681890
YCRE_SCHPOtrs130genetic
22681890
IDHP_SCHPOidp1genetic
22681890
NSE6_SCHPOnse6genetic
22681890
TAL1_SCHPOtal1genetic
22681890
PUB1_SCHPOpub1genetic
22681890
NU132_SCHPOnup132genetic
22681890
REB1_SCHPOreb1genetic
22681890
BQT4_SCHPObqt4genetic
22681890
YEG5_SCHPOmga2genetic
22681890
6PGL_SCHPOSPCC16C4.10genetic
22681890
YCGK_SCHPOSPCC16C4.20cgenetic
22681890
G3P2_SCHPOgpd3genetic
22681890
RTF2_SCHPOrtf2genetic
22681890
VAM7_SCHPOSPCC594.06cgenetic
22681890
ARP6_SCHPOarp6genetic
22681890
RL30A_SCHPOrpl3001genetic
22681890
ERG28_SCHPOerg28genetic
22681890
PFA3_SCHPOpfa3genetic
22681890
GOS1_SCHPOgos1genetic
22681890
ADK_SCHPOado1genetic
22681890
YK82_SCHPObdf2genetic
22681890
MTO1_SCHPOSPBC30B4.06cgenetic
22681890
BST1_SCHPObst1genetic
22681890
CWF16_SCHPOcwf16genetic
22681890
YGRG_SCHPOSPBC365.16genetic
22681890
UAF30_SCHPOspp27genetic
22681890
HRQ1_SCHPOhrq1genetic
22681890
U390_SCHPOSPCC24B10.18genetic
22681890
BUN62_SCHPObun62genetic
22681890
FUS1_SCHPOfus1genetic
22681890
YGBA_SCHPOSPBC25B2.10genetic
22681890
KCC2_SCHPOcmk2genetic
22681890
YAJE_SCHPOSPAC30D11.14cgenetic
22681890
HOB3_SCHPOhob3genetic
22681890
YAQD_SCHPOSPAC18G6.13genetic
22681890
MUG80_SCHPOmug80genetic
22681890
POM1_SCHPOpom1genetic
22681890
DSC4_SCHPOdsc4genetic
22681890
CHO2_SCHPOcho2genetic
22681890
VPS38_SCHPOvps38genetic
22681890
NU124_SCHPOnup124genetic
22681890
SCS7_SCHPOscs7genetic
22681890
MUG20_SCHPOmug20genetic
22681890
TR112_SCHPOtrm112genetic
22681890
YO48_SCHPOSPBC36B7.08cgenetic
22681890
ATP14_SCHPOatp14genetic
22681890
CYB51_SCHPOSPBC29A10.16cgenetic
22681890
ATPB_SCHPOatp2genetic
22681890
PUR9_SCHPOade10genetic
22681890
POF3_SCHPOpof3genetic
22681890
ELP1_SCHPOelp1genetic
22681890
YBKD_SCHPOgmh6genetic
22681890
RENT1_SCHPOupf1genetic
22681890
ASK1_SCHPOask1genetic
22681890
YCY1_SCHPOSPCC1235.01genetic
22681890
DGK1_SCHPOptp4genetic
22681890
YB33_SCHPOebs1genetic
22681890
RL10B_SCHPOrpl1002genetic
22681890
DAD2_SCHPOdad2genetic
22681890
YCPE_SCHPOtrp663genetic
22681890
H2AZ_SCHPOpht1genetic
22681890
IMA2_SCHPOimp1genetic
22681890
DIP1_SCHPOdip1genetic
22681890
DOP1_SCHPOSPAPB21F2.02genetic
22681890
PRZ1_SCHPOprz1genetic
22681890
MCL1_SCHPOmcl1genetic
22681890
CSK1_SCHPOcsk1genetic
22681890
YKEE_SCHPOSPAC1805.14genetic
22681890
RF1M_SCHPOmrf1genetic
22681890
YOX1_SCHPOyox1genetic
22681890
TSN1_SCHPOtsn1physical
24382491
YJQ5_SCHPOpwi1physical
26771498
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SRP1_SCHPO

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-115; SER-117; SER-119;SER-125; SER-127; TYR-129; SER-154; SER-156; TYR-159; SER-170; SER-172AND SER-181, AND MASS SPECTROMETRY.

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