SRP2_SCHPO - dbPTM
SRP2_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SRP2_SCHPO
UniProt AC P78814
Protein Name Pre-mRNA-splicing factor srp2
Gene Name srp2
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 365
Subcellular Localization Nucleus .
Protein Description Has a role in pre-mRNA splicing where it is involved in spliceosome assembly..
Protein Sequence MSETRLFVGRIPPQATREDMMDFFKGYGQILDCKLMNGFGFVEVEDARDARDIVNDFQGKEFMGSRIVVEPARGERRRRENFRESAASKYPRPRRTGFRLIVENLSEDVSWQDLKDVMRKAGEPTFTDAHRENPGAGVVEFSTEEDMRNALTSLNGEVIKGQAVTLREDPDAANEPLPEVPSRFRSRSPPARRRYRDDYRRGGDYRRDAYRPGRDDERRYAPRGEYRRNNRDEYRRGGRDEYRRNSRSDYRRPHDDEYRRPRGDEYRPGRDEYRRSRDDGRPSHDDEYRRDAYSRSPSPRRDREENRSPAYEGSKSYSAAPEASMESSAPTESYDKPAASEEQQPLQNHSDVGNGSAEGQVAAEW
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
153PhosphorylationDMRNALTSLNGEVIK
HHHHHHHHHCCEEEC		22.2325720772
186PhosphorylationEVPSRFRSRSPPARR
CCCHHHHCCCCCHHH		34.1028889911
188PhosphorylationPSRFRSRSPPARRRY
CHHHHCCCCCHHHHH		36.1628889911
276PhosphorylationGRDEYRRSRDDGRPS
CCHHHHCCCCCCCCC		30.9428889911
283PhosphorylationSRDDGRPSHDDEYRR
CCCCCCCCCCHHHHH		37.8829996109
293PhosphorylationDEYRRDAYSRSPSPR
HHHHHHHHHCCCCCC		14.6529996109
294PhosphorylationEYRRDAYSRSPSPRR
HHHHHHHHCCCCCCC		28.1828889911
296PhosphorylationRRDAYSRSPSPRRDR
HHHHHHCCCCCCCCC		24.6428889911
298PhosphorylationDAYSRSPSPRRDREE
HHHHCCCCCCCCCCH		32.0828889911
308PhosphorylationRDREENRSPAYEGSK
CCCCHHCCCCCCCCC		26.0128889911
311PhosphorylationEENRSPAYEGSKSYS
CHHCCCCCCCCCCCC		24.9829996109
314PhosphorylationRSPAYEGSKSYSAAP
CCCCCCCCCCCCCCC		13.3929996109
316PhosphorylationPAYEGSKSYSAAPEA
CCCCCCCCCCCCCHH		26.4724763107
318PhosphorylationYEGSKSYSAAPEASM
CCCCCCCCCCCHHHC		25.6627738172
324PhosphorylationYSAAPEASMESSAPT
CCCCCHHHCCCCCCC		22.7827738172
356PhosphorylationHSDVGNGSAEGQVAA
CCCCCCCCCCCCCEE		27.4427738172
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SRP2_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SRP2_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SRP2_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
DSK1_SCHPOdsk1physical
12186627
DSK1_SCHPOdsk1physical
10629038
SRP1_SCHPOsrp1physical
12186627
CYB51_SCHPOSPBC29A10.16cgenetic
22681890
MCL1_SCHPOmcl1genetic
22681890
SRP2_SCHPOsrp2physical
26771498
SRP1_SCHPOsrp1physical
26771498
DSK1_SCHPOdsk1physical
26771498
YJQ5_SCHPOpwi1physical
26771498
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SRP2_SCHPO

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-186; SER-188; SER-276;SER-294; SER-296; SER-298 AND SER-308, AND MASS SPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory