GCST_YEAST - dbPTM
GCST_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID GCST_YEAST
UniProt AC P48015
Protein Name Aminomethyltransferase, mitochondrial
Gene Name GCV1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 400
Subcellular Localization Mitochondrion.
Protein Description The glycine cleavage system (glycine decarboxylase complex) catalyzes the degradation of glycine..
Protein Sequence MSIIKKIVFKRFNSTLKKTALHDLHVSLGGTMVPYAGYSMPVLYKGQTHIESHNWTRTNAGLFDVSHMLQSKLSGPHSVKFLQRVTPTDFNALPVGSGTLSVLLNPQGGVVDDTIITKENDDNEFYIVTNAGCAERDTEFFHDELQNGSTLDCQWKIIEGRSLLALQGPKAKDVLEPLLSKTAPGKDLKELFFGQRHEFALKDGSLVQIARGGYTGEDGFEISIANEKAVEFAEQLLANPVMKPIGLAARDSLRLEAGMCLYGHELDESITPVEAALNWVISKSRRDLVDQKYWFNGYAKIMDQLNNKTYSKVRVGFKYLKKGPAARNGVKIFLPDAETEVGLVTSGSASPTLNNINIGQAYVQKGYHKKGTKLLVQVRNKFYPIELAKMPLVPTHYYKQ
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
72AcetylationVSHMLQSKLSGPHSV
HHHHHHHHHCCCCHH
33.4424489116
80AcetylationLSGPHSVKFLQRVTP
HCCCCHHEEHCCCCC
43.2924489116
181AcetylationVLEPLLSKTAPGKDL
HHHHHHCCCCCCCCH
48.9924489116
189AcetylationTAPGKDLKELFFGQR
CCCCCCHHHHHCCCE
63.6124489116
202AcetylationQRHEFALKDGSLVQI
CEEEEEECCCCEEEE
57.5224489116
292AcetylationRRDLVDQKYWFNGYA
HHHHCCCHHHHHHHH
39.7324489116
308SuccinylationIMDQLNNKTYSKVRV
HHHHHCCCCCCEEEE
48.0123954790
381AcetylationLLVQVRNKFYPIELA
EEEEECCCCCCCCCC
35.3924489116
389AcetylationFYPIELAKMPLVPTH
CCCCCCCCCCCCCCC
54.3924489116
399AcetylationLVPTHYYKQ------
CCCCCCCCC------
42.2224489116
399SuccinylationLVPTHYYKQ------
CCCCCCCCC------
42.2223954790

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of GCST_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of GCST_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of GCST_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
GLYM_YEASTSHM1genetic
16941010
GLYC_YEASTSHM2genetic
16941010
I23O_YEASTBNA2genetic
16941010
KYNU_YEASTBNA5genetic
16941010
SERC_YEASTSER1genetic
16941010
SERB_YEASTSER2genetic
16941010
SERA_YEASTSER3genetic
16941010
SER33_YEASTSER33genetic
16941010
FABG_YEASTOAR1genetic
21623372
QCR1_YEASTCOR1genetic
21623372
PDX3_YEASTPDX3genetic
21623372
PRS6B_YEASTRPT3genetic
27708008
MOB2_YEASTMOB2genetic
27708008
SWC3_YEASTSWC3genetic
27708008
SEF1_YEASTSEF1genetic
27708008
RS17B_YEASTRPS17Bgenetic
27708008
ACA1_YEASTACA1genetic
27708008
AIM11_YEASTAIM11genetic
27708008
YFF2_YEASTYFL052Wgenetic
27708008
YG036_YEASTYGL036Wgenetic
27708008
ARO8_YEASTARO8genetic
27708008
MTC3_YEASTMTC3genetic
27708008
RS25A_YEASTRPS25Agenetic
27708008
RL11B_YEASTRPL11Bgenetic
27708008
DRN1_YEASTDRN1genetic
27708008
YG3A_YEASTYGR130Cgenetic
27708008
TBP7_YEASTYTA7genetic
27708008
SLT2_YEASTSLT2genetic
27708008
MED20_YEASTSRB2genetic
27708008
PRY1_YEASTPRY1genetic
27708008
MRX5_YEASTYJL147Cgenetic
27708008
IXR1_YEASTIXR1genetic
27708008
TCTP_YEASTTMA19genetic
27708008
FRMSR_YEASTYKL069Wgenetic
27708008
CYT2_YEASTCYT2genetic
27708008
RS21A_YEASTRPS21Agenetic
27708008
ENT4_YEASTENT4genetic
27708008
SIC1_YEASTSIC1genetic
27708008
EIF3J_YEASTHCR1genetic
27708008
LIPB_YEASTLIP2genetic
27708008
PLB2_YEASTPLB2genetic
27708008
GYL1_YEASTGYL1genetic
27708008
DIA1_YEASTDIA1genetic
27708008
HDA1_YEASTHDA1genetic
27708008
PMS1_YEASTPMS1genetic
27708008
MKT1_YEASTMKT1genetic
27708008
CYC2_YEASTCYC2genetic
27708008
BUD21_YEASTBUD21genetic
27708008
VAM3_YEASTVAM3genetic
27708008
RS10A_YEASTRPS10Agenetic
27708008
YO385_YEASTYOR385Wgenetic
27708008
PMA2_YEASTPMA2genetic
27708008
POC4_YEASTPOC4genetic
27708008
SRO7_YEASTSRO7genetic
27708008
NAA30_YEASTMAK3genetic
27708008
SPEE_YEASTSPE3genetic
27708008
MED1_YEASTMED1genetic
27708008
RFA1_YEASTRFA1genetic
27708008
SEC17_YEASTSEC17genetic
27708008
CALM_YEASTCMD1genetic
27708008
CDK1_YEASTCDC28genetic
27708008
GLE1_YEASTGLE1genetic
27708008
MSS4_YEASTMSS4genetic
27708008
SNU56_YEASTSNU56genetic
27708008
TSC11_YEASTTSC11genetic
27708008
ACT_YEASTACT1genetic
27708008
PRS8_YEASTRPT6genetic
27708008
RCC1_YEASTSRM1genetic
27708008
HSP77_YEASTSSC1genetic
27708008
SEC22_YEASTSEC22genetic
27708008
GSP1_YEASTGSP1genetic
27708008
RU1C_YEASTYHC1genetic
27708008
RLA0_YEASTRPP0genetic
27708008
IMB1_YEASTKAP95genetic
27708008
PRP24_YEASTPRP24genetic
27708008
NOG2_YEASTNOG2genetic
27708008
TYSY_YEASTCDC21genetic
27708008
SMP3_YEASTSMP3genetic
27708008
MED4_YEASTMED4genetic
27708008
ULP1_YEASTULP1genetic
27708008
ARP7_YEASTARP7genetic
27708008
BUR1_YEASTSGV1genetic
27708008
POF1_YEASTPOF1genetic
27708008
IMG2_YEASTIMG2genetic
27708008
CSM1_YEASTCSM1genetic
27708008
PSP1_YEASTPSP1genetic
27708008
STL1_YEASTSTL1genetic
27708008
PAD1_YEASTPAD1genetic
27708008
YD541_YEASTYDR541Cgenetic
27708008
JHD1_YEASTJHD1genetic
27708008
SLX8_YEASTSLX8genetic
27708008
KC13_YEASTYCK3genetic
27708008
PMD1_YEASTPMD1genetic
27708008
BUD27_YEASTBUD27genetic
27708008
PALF_YEASTRIM8genetic
27708008
MDM34_YEASTMDM34genetic
27708008
PHB1_YEASTPHB1genetic
27708008
PHB2_YEASTPHB2genetic
27708008
YHA8_YEASTYHL008Cgenetic
27708008
GOSR1_YEASTGOS1genetic
27708008
CYPB_YEASTCPR2genetic
27708008
EPT1_YEASTEPT1genetic
27708008
IGO2_YEASTIGO2genetic
27708008
FMC1_YEASTFMC1genetic
27708008
DPH1_YEASTDPH1genetic
27708008
HPM1_YEASTHPM1genetic
27708008
FLX1_YEASTFLX1genetic
27708008
SDHX_YEASTYJL045Wgenetic
27708008
PHO86_YEASTPHO86genetic
27708008
RPE_YEASTRPE1genetic
27708008
ATG36_YEASTATG36genetic
27708008
YJ68_YEASTYJR098Cgenetic
27708008
PUT3_YEASTPUT3genetic
27708008
PIR1_YEASTPIR1genetic
27708008
DCOR_YEASTSPE1genetic
27708008
VPS51_YEASTVPS51genetic
27708008
DBP7_YEASTDBP7genetic
27708008
BPT1_YEASTBPT1genetic
27708008
COX12_YEASTCOX12genetic
27708008
RAX2_YEASTRAX2genetic
27708008
TOP3_YEASTTOP3genetic
27708008
THI7_YEASTTHI7genetic
27708008
YL257_YEASTYLR257Wgenetic
27708008
ROM2_YEASTROM2genetic
27708008
TSR2_YEASTTSR2genetic
27708008
COG8_YEASTCOG8genetic
27708008
VPS9_YEASTVPS9genetic
27708008
BUL2_YEASTBUL2genetic
27708008
EIS1_YEASTEIS1genetic
27708008
SIP5_YEASTSIP5genetic
27708008
OSW5_YEASTOSW5genetic
27708008
YM35_YEASTYMR160Wgenetic
27708008
YHM2_YEASTYHM2genetic
27708008
PABC_YEASTABZ2genetic
27708008
DOM34_YEASTDOM34genetic
27708008
YNF0_YEASTYNL050Cgenetic
27708008
FAR11_YEASTFAR11genetic
27708008
FKBP_YEASTFPR1genetic
27708008
LSM7_YEASTLSM7genetic
27708008
SWM2_YEASTSWM2genetic
27708008
COQ2_YEASTCOQ2genetic
27708008
MDHC_YEASTMDH2genetic
27708008
VPS17_YEASTVPS17genetic
27708008
MPC54_YEASTMPC54genetic
27708008
ECM23_YEASTECM23genetic
27708008
RTC6_YEASTRTC6genetic
27708008
MDM36_YEASTMDM36genetic
27708008
KAR3_YEASTKAR3genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of GCST_YEAST

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Related Literatures of Post-Translational Modification

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