FIG1_YEAST - dbPTM
FIG1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID FIG1_YEAST
UniProt AC P38224
Protein Name Factor-induced gene 1 protein
Gene Name FIG1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 298
Subcellular Localization Membrane
Multi-pass membrane protein .
Protein Description Required for efficient mating..
Protein Sequence MVAISMIWFFTKRMPRIFALAFNLISIFLLIFLLIGCYNPSNQSTFLVKYKFDDNSPFYTIIEKSYEKSNTTLGLEEVIIRSGYMGVCIDNIPSQYSSYNNMTTFSNSICYARKNLSSVPLYRDLEIQLSNIASSSSKTQSSVVLNILKLAQLTSVNVIHPYVLMATVILTILMFLFILYVTVPKLPFKLAVNKFLLLLSSTIVLTWGIGAMWTHVGINASYRLVPSSSMNIITVKKGKKAAVMAWFSFAFLLLDSVVLWLIFLRDRKSLKDEIDNVPCAQNRYNNYSSDSSTLHSKV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
5Phosphorylation---MVAISMIWFFTK
---CCHHHHHHHHHC		8.4228132839
50PhosphorylationQSTFLVKYKFDDNSP
CCEEEEEEEECCCCC		14.9227017623
56PhosphorylationKYKFDDNSPFYTIIE
EEEECCCCCEEEEEE		24.3127017623
59PhosphorylationFDDNSPFYTIIEKSY
ECCCCCEEEEEEHHH		10.6228132839
60PhosphorylationDDNSPFYTIIEKSYE
CCCCCEEEEEEHHHC		18.8327017623
66PhosphorylationYTIIEKSYEKSNTTL
EEEEEHHHCCCCCCC		38.1428132839
227PhosphorylationASYRLVPSSSMNIIT
CCEEECCCCCCEEEE		27.8026447709
228PhosphorylationSYRLVPSSSMNIITV
CEEECCCCCCEEEEE		27.7726447709
229PhosphorylationYRLVPSSSMNIITVK
EEECCCCCCEEEEEE		21.8626447709
234PhosphorylationSSSMNIITVKKGKKA
CCCCEEEEEECCHHH		23.6026447709
288PhosphorylationQNRYNNYSSDSSTLH
HCCCCCCCCCCCCCC		29.7717330950
289PhosphorylationNRYNNYSSDSSTLHS
CCCCCCCCCCCCCCC		31.0217330950
291PhosphorylationYNNYSSDSSTLHSKV
CCCCCCCCCCCCCCC		27.4617330950
292PhosphorylationNNYSSDSSTLHSKV-
CCCCCCCCCCCCCC-		39.7217330950
293PhosphorylationNYSSDSSTLHSKV--
CCCCCCCCCCCCC--		32.2317330950
296PhosphorylationSDSSTLHSKV-----
CCCCCCCCCC-----		37.9217330950
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of FIG1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of FIG1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of FIG1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
FIG2_YEASTFIG2genetic
9456310
FIG4_YEASTFIG4genetic
9456310
MID1_YEASTMID1genetic
21511333
CCH1_YEASTCCH1genetic
21511333
ELO2_YEASTELO2genetic
27708008
RMD1_YEASTRMD1genetic
27708008
YD129_YEASTYDL129Wgenetic
27708008
ATG9_YEASTATG9genetic
27708008
YD180_YEASTYDL180Wgenetic
27708008
YD042_YEASTYDR042Cgenetic
27708008
METE_YEASTMET6genetic
27708008
SWI4_YEASTSWI4genetic
27708008
RS26B_YEASTRPS26Bgenetic
27708008
RIM15_YEASTRIM15genetic
27708008
SGF73_YEASTSGF73genetic
27708008
YGI2_YEASTYGL082Wgenetic
27708008
GPG1_YEASTGPG1genetic
27708008
NMA2_YEASTNMA2genetic
27708008
MTL1_YEASTMTL1genetic
27708008
FHN1_YEASTFHN1genetic
27708008
UBR1_YEASTUBR1genetic
27708008
SLI1_YEASTSLI1genetic
27708008
SCW4_YEASTSCW4genetic
27708008
PPME1_YEASTPPE1genetic
27708008
PTH_YEASTPTH1genetic
27708008
PYR1_YEASTURA2genetic
27708008
STB6_YEASTSTB6genetic
27708008
UTH1_YEASTUTH1genetic
27708008
PCKA_YEASTPCK1genetic
27708008
ENT4_YEASTENT4genetic
27708008
YLL53_YEASTYLL053Cgenetic
27708008
YL012_YEASTYLR012Cgenetic
27708008
CHA4_YEASTCHA4genetic
27708008
YL224_YEASTYLR224Wgenetic
27708008
TSA1_YEASTTSA1genetic
27708008
BUL2_YEASTBUL2genetic
27708008
AVO2_YEASTAVO2genetic
27708008
YM58_YEASTYMR206Wgenetic
27708008
NGL2_YEASTNGL2genetic
27708008
TDA1_YEASTTDA1genetic
27708008
IDH1_YEASTIDH1genetic
27708008
ATG3_YEASTATG3genetic
27708008
SDHF2_YEASTSDH5genetic
27708008
HMI1_YEASTHMI1genetic
27708008
ZEO1_YEASTZEO1genetic
27708008
RGA1_YEASTRGA1genetic
27708008
MRS2_YEASTMRS2genetic
27708008
RL21B_YEASTRPL21Bgenetic
27708008
NCBP2_YEASTCBC2genetic
27708008
KAR3_YEASTKAR3genetic
27708008
HSP71_YEASTSSA1genetic
27708008
PUR7_YEASTADE1genetic
27708008
SSH1_YEASTSSH1genetic
27708008
RV161_YEASTRVS161genetic
27708008
NPP1_YEASTNPP1genetic
27708008
ABP1_YEASTABP1genetic
27708008
ADH7_YEASTADH7genetic
27708008
SLX5_YEASTSLX5genetic
27708008
PHO2_YEASTPHO2genetic
27708008
LCMT1_YEASTPPM1genetic
27708008
AGE1_YEASTAGE1genetic
27708008
SERA_YEASTSER3genetic
27708008
FLO8_YEASTFLO8genetic
27708008
TAPT1_YEASTEMP65genetic
27708008
MSH4_YEASTMSH4genetic
27708008
IES1_YEASTIES1genetic
27708008
YFF1_YEASTYFL051Cgenetic
27708008
LSB3_YEASTLSB3genetic
27708008
RT31_YEASTYMR31genetic
27708008
MED5_YEASTNUT1genetic
27708008
DSD1_YEASTDSD1genetic
27708008
STF2_YEASTSTF2genetic
27708008
TAL2_YEASTNQM1genetic
27708008
VOA1_YEASTVOA1genetic
27708008
ECL1_YEASTECL1genetic
27708008
CRH1_YEASTCRH1genetic
27708008
SNG1_YEASTSNG1genetic
27708008
PMT6_YEASTPMT6genetic
27708008
YG51_YEASTYGR237Cgenetic
27708008
TNA1_YEASTTNA1genetic
27708008
SAY1_YEASTSAY1genetic
27708008
YG5Q_YEASTYGR273Cgenetic
27708008
VMR1_YEASTVMR1genetic
27708008
GGA2_YEASTGGA2genetic
27708008
SPL2_YEASTSPL2genetic
27708008
CSK21_YEASTCKA1genetic
27708008
YIQ3_YEASTYIL163Cgenetic
27708008
GPX3_YEASTHYR1genetic
27708008
PRY3_YEASTPRY3genetic
27708008
TAX4_YEASTTAX4genetic
27708008
MET3_YEASTMET3genetic
27708008
YJ31_YEASTYJR061Wgenetic
27708008
HIR3_YEASTHIR3genetic
27708008
RL14A_YEASTRPL14Agenetic
27708008
YKD3A_YEASTYKL033W-Agenetic
27708008
ZRT3_YEASTZRT3genetic
27708008
RL8B_YEASTRPL8Bgenetic
27708008
YL040_YEASTAFB1genetic
27708008
SWI6_YEASTSWI6genetic
27708008
DUS4_YEASTDUS4genetic
27708008
VIP1_YEASTVIP1genetic
27708008
YMF3_YEASTYML053Cgenetic
27708008
YMP0_YEASTYMR010Wgenetic
27708008
YMP8_YEASTYMR018Wgenetic
27708008
BUB2_YEASTBUB2genetic
27708008
YM085_YEASTYMR085Wgenetic
27708008
CAT8_YEASTCAT8genetic
27708008
PUR1_YEASTADE4genetic
27708008
FAP1_YEASTFAP1genetic
27708008
LKHA4_YEASTLAP2genetic
27708008
APP1_YEASTAPP1genetic
27708008
TOM70_YEASTTOM70genetic
27708008
BIOD_YEASTBIO4genetic
27708008
YO13A_YEASTYOL013W-Agenetic
27708008
HPF1_YEASTHPF1genetic
27708008
MSA1_YEASTMSA1genetic
27708008
VAM10_YEASTVAM10genetic
27708008
NRT1_YEASTNRT1genetic
27708008
OST3_YEASTOST3genetic
27708008
KTR1_YEASTKTR1genetic
27708008
PUS7_YEASTPUS7genetic
27708008
VPH1_YEASTVPH1genetic
27708008
RAX1_YEASTRAX1genetic
27708008
DGK1_YEASTDGK1genetic
27708008
ULA1_YEASTULA1genetic
27708008
PMA2_YEASTPMA2genetic
27708008
TGS1_YEASTTGS1genetic
27708008
KAR9_YEASTKAR9genetic
27708008
AGC1_YEASTAGC1genetic
27708008
AXL1_YEASTAXL1genetic
27708008
MET16_YEASTMET16genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of FIG1_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Large-scale phosphorylation analysis of alpha-factor-arrestedSaccharomyces cerevisiae.";
Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,Elias J.E., Gygi S.P.;
J. Proteome Res. 6:1190-1197(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-288; THR-293 ANDSER-296, AND MASS SPECTROMETRY.

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