dbPTM

FOXB1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	FOXB1_HUMAN
UniProt AC	Q99853
Protein Name	Forkhead box protein B1
Gene Name	FOXB1
Organism	Homo sapiens (Human).
Sequence Length	325
Subcellular Localization	Nucleus .
Protein Description
Protein Sequence	MPRPGRNTYSDQKPPYSYISLTAMAIQSSPEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPSCGDMFENGSFLRRRKRFKVLKSDHLAPSKPADAAQYLQQQAKLRLSALAASGTHLPQMPAAAYNLGGVAQPSGFKHPFAIENIIAREYKMPGGLAFSAMQPVPAAYPLPNQLTTMGSSLGTGWPHVYGSAGMIDSATPISMASGDYSAYGVPLKPLCHAAGQTLPAIPVPIKPTPAAVPALPALPAPIPTLLSNSPPSLSPTSSQTATSQSSPATPSETLTSPASALHSVAVH

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Phosphorylation	YSDQKPPYSYISLTA CCCCCCCCCEEEHHH	23.72	-
18	Phosphorylation	DQKPPYSYISLTAMA CCCCCCCEEEHHHHH	6.67	-
40	Phosphorylation	MLPLSEIYKFIMDRF HCCHHHHHHHHHHHC	8.87	22817900
121	Acetylation	SDHLAPSKPADAAQY CCCCCCCCHHHHHHH	43.07	26051181
321	Phosphorylation	SPASALHSVAVH--- CCHHHHHHHCCC---	16.78	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of FOXB1_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of FOXB1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of FOXB1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PHF5A_HUMAN	PHF5A	physical	21988832
K1C40_HUMAN	KRT40	physical	25416956
KR108_HUMAN	KRTAP10-8	physical	25416956
KR103_HUMAN	KRTAP10-3	physical	25416956
NT2NL_HUMAN	NOTCH2NL	physical	25416956
SYYC_HUMAN	YARS	physical	25609649
DX39A_HUMAN	DDX39A	physical	25609649
SCRIB_HUMAN	SCRIB	physical	25609649
NSMA3_HUMAN	SMPD4	physical	25609649
TLE3_HUMAN	TLE3	physical	25609649
ARI3A_HUMAN	ARID3A	physical	25609649
TF3C1_HUMAN	GTF3C1	physical	25609649
IMA5_HUMAN	KPNA1	physical	25609649
PDS5A_HUMAN	PDS5A	physical	25609649
CCAR2_HUMAN	CCAR2	physical	25609649
SYMPK_HUMAN	SYMPK	physical	25609649
SYVC_HUMAN	VARS	physical	25609649
HEAT1_HUMAN	HEATR1	physical	25609649
RALY_HUMAN	RALY	physical	25609649
SATB2_HUMAN	SATB2	physical	25609649
SYIC_HUMAN	IARS	physical	25609649
RM38_HUMAN	MRPL38	physical	25609649
NU205_HUMAN	NUP205	physical	25609649
SF3B1_HUMAN	SF3B1	physical	25609649
DSRAD_HUMAN	ADAR	physical	25609649
ARI3B_HUMAN	ARID3B	physical	25609649
BTAF1_HUMAN	BTAF1	physical	25609649
COPA_HUMAN	COPA	physical	25609649
ECM29_HUMAN	KIAA0368	physical	25609649
SYLC_HUMAN	LARS	physical	25609649
SYDM_HUMAN	DARS2	physical	25609649
G45IP_HUMAN	GADD45GIP1	physical	25609649
TF3C4_HUMAN	GTF3C4	physical	25609649
TF3C5_HUMAN	GTF3C5	physical	25609649
HIC2_HUMAN	HIC2	physical	25609649
HUWE1_HUMAN	HUWE1	physical	25609649
RM03_HUMAN	MRPL3	physical	25609649
NSDHL_HUMAN	NSDHL	physical	25609649
PA2G4_HUMAN	PA2G4	physical	25609649
KAISO_HUMAN	ZBTB33	physical	25609649
CTBP2_HUMAN	CTBP2	physical	25609649
DYHC1_HUMAN	DYNC1H1	physical	25609649
GAPD1_HUMAN	GAPVD1	physical	25609649
HNRL2_HUMAN	HNRNPUL2	physical	25609649
HXA10_HUMAN	HOXA10	physical	25609649
LRP1_HUMAN	LRP1	physical	25609649
NOVA1_HUMAN	NOVA1	physical	25609649
RCC1_HUMAN	RCC1	physical	25609649
SATB1_HUMAN	SATB1	physical	25609649
SUGP2_HUMAN	SUGP2	physical	25609649
ZFHX4_HUMAN	ZFHX4	physical	25609649
SYDC_HUMAN	DARS	physical	25609649
IF4G1_HUMAN	EIF4G1	physical	25609649
FUBP3_HUMAN	FUBP3	physical	25609649
HXD13_HUMAN	HOXD13	physical	25609649
UFL1_HUMAN	UFL1	physical	25609649
LMNB2_HUMAN	LMNB2	physical	25609649
RM20_HUMAN	MRPL20	physical	25609649
RM24_HUMAN	MRPL24	physical	25609649
CND2_HUMAN	NCAPH	physical	25609649
NOVA2_HUMAN	NOVA2	physical	25609649
SAC1_HUMAN	SACM1L	physical	25609649
SMC2_HUMAN	SMC2	physical	25609649
STAG2_HUMAN	STAG2	physical	25609649
UBR5_HUMAN	UBR5	physical	25609649
WAPL_HUMAN	WAPAL	physical	25609649
XPO7_HUMAN	XPO7	physical	25609649
TYY1_HUMAN	YY1	physical	25609649
SYAM_HUMAN	AARS2	physical	25609649
AN32C_HUMAN	ANP32C	physical	25609649
COG5_HUMAN	COG5	physical	25609649
COPG1_HUMAN	COPG1	physical	25609649
CTNB1_HUMAN	CTNNB1	physical	25609649
CTND1_HUMAN	CTNND1	physical	25609649
DYR_HUMAN	DHFR	physical	25609649
DUS9_HUMAN	DUSP9	physical	25609649
E4F1_HUMAN	E4F1	physical	25609649
EF1D_HUMAN	EEF1D	physical	25609649
GBF1_HUMAN	GBF1	physical	25609649
TF3C2_HUMAN	GTF3C2	physical	25609649
TF3C3_HUMAN	GTF3C3	physical	25609649
HXK2_HUMAN	HK2	physical	25609649
HXK3_HUMAN	HK3	physical	25609649
IQGA2_HUMAN	IQGAP2	physical	25609649
LRWD1_HUMAN	LRWD1	physical	25609649
MEN1_HUMAN	MEN1	physical	25609649
RM18_HUMAN	MRPL18	physical	25609649
RM27_HUMAN	MRPL27	physical	25609649
RM50_HUMAN	MRPL50	physical	25609649
RM51_HUMAN	MRPL51	physical	25609649
RT30_HUMAN	MRPS30	physical	25609649
NAA40_HUMAN	NAA40	physical	25609649
CND1_HUMAN	NCAPD2	physical	25609649
NDUV2_HUMAN	NDUFV2	physical	25609649
NOC2L_HUMAN	NOC2L	physical	25609649
NU160_HUMAN	NUP160	physical	25609649
DPOE1_HUMAN	POLE	physical	25609649
PRP31_HUMAN	PRPF31	physical	25609649
SYQ_HUMAN	QARS	physical	25609649
RBP2_HUMAN	RANBP2	physical	25609649
RAGP1_HUMAN	RANGAP1	physical	25609649
RIF1_HUMAN	RIF1	physical	25609649
SALL1_HUMAN	SALL1	physical	25609649
SF3A3_HUMAN	SF3A3	physical	25609649
SIX5_HUMAN	SIX5	physical	25609649
SKP2_HUMAN	SKP2	physical	25609649
SMCA5_HUMAN	SMARCA5	physical	25609649
SMC1A_HUMAN	SMC1A	physical	25609649
SMC3_HUMAN	SMC3	physical	25609649
SMC4_HUMAN	SMC4	physical	25609649
AP2A_HUMAN	TFAP2A	physical	25609649
TLE1_HUMAN	TLE1	physical	25609649
TLE4_HUMAN	TLE4	physical	25609649
TOM40_HUMAN	TOMM40	physical	25609649
P53_HUMAN	TP53	physical	25609649
UBE4A_HUMAN	UBE4A	physical	25609649
ZBT40_HUMAN	ZBTB40	physical	25609649
ZFR_HUMAN	ZFR	physical	25609649
ZN131_HUMAN	ZNF131	physical	25609649
PARP2_HUMAN	PARP2	physical	25609649
CHD1L_HUMAN	CHD1L	physical	25609649
NHEJ1_HUMAN	NHEJ1	physical	25609649
DNLI3_HUMAN	LIG3	physical	25609649
PAXX_HUMAN	C9orf142	physical	25609649
H2AY_HUMAN	H2AFY	physical	25609649
DNLI4_HUMAN	LIG4	physical	25609649
RFA2_HUMAN	RPA2	physical	25609649
XRCC1_HUMAN	XRCC1	physical	25609649
RFA3_HUMAN	RPA3	physical	25609649

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of FOXB1_HUMAN

Related Literatures of Post-Translational Modification