AN32C_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AN32C_HUMAN
• UniProt AC: O43423
• Protein Name: Acidic leucine-rich nuclear phosphoprotein 32 family member C
• Gene Name: ANP32C
• Organism: Homo sapiens (Human).
• Sequence Length: 234
• Protein Sequence: MEMGRRIHSELRNRAPSDVKELALDNSRSNEGKLEALTDEFEELEFLSKINGGLTSISDLPKLKLRKLELRVSGGLEVLAEKCPNLTHLYLSGNKIKDLSTIEPLKQLENLKSLDLFNCEVTNLNDYGENVFKLLLQLTYLDSCYWDHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEEDEEELGEEERGQKRK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
29	Phosphorylation	LALDNSRSNEGKLEA HHHCCCCCCCHHHHH	38.77	23663014
55	Phosphorylation	SKINGGLTSISDLPK HHHCCCCCCHHHCCC	27.56	21406692
56	Phosphorylation	KINGGLTSISDLPKL HHCCCCCCHHHCCCC	25.74	21406692
58	Phosphorylation	NGGLTSISDLPKLKL CCCCCCHHHCCCCCC	32.63	23403867
73	Phosphorylation	RKLELRVSGGLEVLA CEEEEEECCHHHHHH	22.25	21815630
82	Acetylation	GLEVLAEKCPNLTHL HHHHHHHHCCCCCEE	49.76	26051181
87	Phosphorylation	AEKCPNLTHLYLSGN HHHCCCCCEEEECCC	19.24	50565687
97	Acetylation	YLSGNKIKDLSTIEP EECCCCCCCCCCCHH	54.98	26051181
97	Ubiquitination	YLSGNKIKDLSTIEP EECCCCCCCCCCCHH	54.98	32015554
100	Phosphorylation	GNKIKDLSTIEPLKQ CCCCCCCCCCHHHHH	37.16	54887293
101	Phosphorylation	NKIKDLSTIEPLKQL CCCCCCCCCHHHHHH	36.34	28857561
139	Phosphorylation	FKLLLQLTYLDSCYW HHHHHHHHHHHHCCC	14.74	25690035

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AN32C_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AN32C_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AN32C_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of AN32C_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.