dbPTM

TSC1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TSC1_MOUSE
UniProt AC	Q9EP53
Protein Name	Hamartin
Gene Name	Tsc1
Organism	Mus musculus (Mouse).
Sequence Length	1161
Subcellular Localization	Cytoplasm . Membrane Peripheral membrane protein . At steady state found in association with membranes.
Protein Description	In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. [PubMed: 16707451 Acts as a co-chaperone for HSP90AA1 facilitating HSP90AA1 chaperoning of protein clients such as kinases, TSC2 and glucocorticoid receptor NR3C1]
Protein Sequence	MAQLANIGELLSMLDSSTLGVRDDVTAIFKESLNSERGPMLVNTLVDYYLETNSQPVLHILTTLQEPHDKHLLDKINEYVGKAATRLSILSLLGHVVRLQPSWKHKLSQAPLLPSLLKCLKMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVTEVYLVHLHASVYALFHRLYGMYPCNFVSFLRSHYSMKENVETFEEVVKPMMEHVRIHPELVTGSKDHELDPRRWKTLETHDVVIECAKISLDPTEASYEDGYSVSHQLSACFPYRSADVTTSPYVDTQNSYGGSTSTPSSSSRLMLFSPPGQLPQSLSSPSTRLLPEPLQASLWSPSAVCGMTTPPTSPGNVPADLSHPYSKAFGTTAGGKGTPSGTPATSPPPAPPCPQDDCVHGSAAQASATAPRKEERADSSRPYLHRQSNDRGLEDPPGSKGSVTLRNLPDFLGDLASEEDSIEKDKEEAAISKELSEITTAEADPVVPRGGFDSPFYRDSLSGSQRKTHSAASGTQGSSVNPEPLHSSLDKHGPDTPKQAFTPIDPPSGSADVSPAGDRDRQTSLETSILTPSPCKIPPQRGVSFGSGQLPPYDHLFEVALPKTACHFVSKKTEELLKKVKGNPEEDCVPSTSPMEVLDRLIEQGAGAHSKELSRLSLPSKSVDWTHFGGSPPSDELRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIRAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYSQLQEQRDTMVTQLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRVELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQSKHPDTTKEVEMMKTAYRKELEKNRSHLLQQNQRLDASQRRVLELESLLAKKDHLLLEQKKYLEDVKSQASGQLLAAESRYEAQRKITRVLELEILDLYGRLEKDGRLRKLEEDRAEAAEAAEERLDCCSDGCTDSLVGHNEEASGHNGETRTSRPGGTRASCGGRVTGGSSSSSSELSTPEKPPSQRFSSRWEPALGEPSSSIPTTVGSLPSSKSFLGMKARELFRNKSESQCDEDSVTMSSSSLSETLKTELGKDSGTENKTSLSLDAPHPSSPNSDNVGQLHIMDYNETHPEHS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Phosphorylation	ANIGELLSMLDSSTL HCHHHHHHHHHHCCC	29.89	29899451
17	Phosphorylation	LLSMLDSSTLGVRDD HHHHHHHCCCCCCCH	27.58	29899451
18	Phosphorylation	LSMLDSSTLGVRDDV HHHHHHCCCCCCCHH	31.33	29899451
26	Phosphorylation	LGVRDDVTAIFKESL CCCCCHHHHHHHHHH	22.49	22006019
295	Phosphorylation	RSADVTTSPYVDTQN CCCCCCCCCCCCCCC	12.60	28285833
308	Phosphorylation	QNSYGGSTSTPSSSS CCCCCCCCCCCCCCC	39.64	25338131
309	Phosphorylation	NSYGGSTSTPSSSSR CCCCCCCCCCCCCCC	39.76	25338131
310	Phosphorylation	SYGGSTSTPSSSSRL CCCCCCCCCCCCCCE	27.55	29899451
321	Phosphorylation	SSRLMLFSPPGQLPQ CCCEEEECCCCCCCC	26.65	22942356
331	Phosphorylation	GQLPQSLSSPSTRLL CCCCCCCCCCCCCCC	45.51	30482847
332	Phosphorylation	QLPQSLSSPSTRLLP CCCCCCCCCCCCCCC	28.32	26643407
334	Phosphorylation	PQSLSSPSTRLLPEP CCCCCCCCCCCCCCC	28.27	26643407
335	Phosphorylation	QSLSSPSTRLLPEPL CCCCCCCCCCCCCCC	28.81	26643407
345	Phosphorylation	LPEPLQASLWSPSAV CCCCCHHHCCCCCCC	19.87	26643407
348	Phosphorylation	PLQASLWSPSAVCGM CCHHHCCCCCCCCCC	17.80	26643407
350	Phosphorylation	QASLWSPSAVCGMTT HHHCCCCCCCCCCCC	28.02	23984901
356	Phosphorylation	PSAVCGMTTPPTSPG CCCCCCCCCCCCCCC	22.79	26643407
357	Phosphorylation	SAVCGMTTPPTSPGN CCCCCCCCCCCCCCC	20.55	26643407
360	Phosphorylation	CGMTTPPTSPGNVPA CCCCCCCCCCCCCCC	49.08	26643407
361	Phosphorylation	GMTTPPTSPGNVPAD CCCCCCCCCCCCCCC	36.26	25266776
370	Phosphorylation	GNVPADLSHPYSKAF CCCCCCCCCCCHHCC	23.98	23984901
373	Phosphorylation	PADLSHPYSKAFGTT CCCCCCCCHHCCCCC	19.85	29899451
374	Phosphorylation	ADLSHPYSKAFGTTA CCCCCCCHHCCCCCC	23.20	29899451
379 (in isoform 2)	Phosphorylation	-	13.66	26160508
379 (in isoform 3)	Phosphorylation	-	13.66	26160508
379 (in isoform 4)	Phosphorylation	-	13.66	26160508
380 (in isoform 2)	Phosphorylation	-	24.55	26160508
380 (in isoform 3)	Phosphorylation	-	24.55	26160508
380 (in isoform 4)	Phosphorylation	-	24.55	26160508
385 (in isoform 2)	Phosphorylation	-	46.24	26160508
385 (in isoform 3)	Phosphorylation	-	46.24	26160508
385 (in isoform 4)	Phosphorylation	-	46.24	26160508
386	Phosphorylation	TTAGGKGTPSGTPAT CCCCCCCCCCCCCCC	20.12	21659605
387 (in isoform 2)	Phosphorylation	-	39.16	26160508
387 (in isoform 3)	Phosphorylation	-	39.16	26160508
387 (in isoform 4)	Phosphorylation	-	39.16	26160508
388	Phosphorylation	AGGKGTPSGTPATSP CCCCCCCCCCCCCCC	55.95	21659605
389 (in isoform 2)	Phosphorylation	-	36.60	26160508
389 (in isoform 3)	Phosphorylation	-	36.60	26160508
389 (in isoform 4)	Phosphorylation	-	36.60	26160508
390	Phosphorylation	GKGTPSGTPATSPPP CCCCCCCCCCCCCCC	17.68	26643407
392 (in isoform 2)	Phosphorylation	-	22.13	26160508
392 (in isoform 3)	Phosphorylation	-	22.13	26160508
392 (in isoform 4)	Phosphorylation	-	22.13	26160508
393	Phosphorylation	TPSGTPATSPPPAPP CCCCCCCCCCCCCCC	42.86	26643407
393 (in isoform 2)	Phosphorylation	-	42.86	26160508
393 (in isoform 3)	Phosphorylation	-	42.86	26160508
393 (in isoform 4)	Phosphorylation	-	42.86	26160508
394	Phosphorylation	PSGTPATSPPPAPPC CCCCCCCCCCCCCCC	37.20	21659605
409 (in isoform 2)	Phosphorylation	-	9.89	24759943
409 (in isoform 3)	Phosphorylation	-	9.89	24759943
409 (in isoform 4)	Phosphorylation	-	9.89	24759943
410	Phosphorylation	QDDCVHGSAAQASAT CCCCCCCHHHHHCCC	12.93	25777480
414 (in isoform 2)	Phosphorylation	-	9.08	26643407
414 (in isoform 3)	Phosphorylation	-	9.08	26643407
414 (in isoform 4)	Phosphorylation	-	9.08	26643407
415	Phosphorylation	HGSAAQASATAPRKE CCHHHHHCCCCCCHH	17.67	25777480
416 (in isoform 2)	Phosphorylation	-	15.70	24759943
416 (in isoform 3)	Phosphorylation	-	15.70	24759943
416 (in isoform 4)	Phosphorylation	-	15.70	24759943
417	Phosphorylation	SAAQASATAPRKEER HHHHHCCCCCCHHHC	34.40	25777480
427	Phosphorylation	RKEERADSSRPYLHR CHHHCCCCCCCCCCH	27.54	19854140
428	Phosphorylation	KEERADSSRPYLHRQ HHHCCCCCCCCCCHH	37.51	29514104
431	Phosphorylation	RADSSRPYLHRQSND CCCCCCCCCCHHCCC	17.65	29514104
436	Phosphorylation	RPYLHRQSNDRGLED CCCCCHHCCCCCCCC	40.43	29899451
447	Phosphorylation	GLEDPPGSKGSVTLR CCCCCCCCCCCEEEC	39.35	29176673
450	Phosphorylation	DPPGSKGSVTLRNLP CCCCCCCCEEECCCC	18.70	29176673
452	Phosphorylation	PGSKGSVTLRNLPDF CCCCCCEEECCCCCH	23.00	29176673
465	Phosphorylation	DFLGDLASEEDSIEK CHHHHHHCCCCHHHH	49.14	21743459
469	Phosphorylation	DLASEEDSIEKDKEE HHHCCCCHHHHHHHH	35.61	21743459
480	Phosphorylation	DKEEAAISKELSEIT HHHHHHHHHHHHHHC	18.49	21743459
484	Phosphorylation	AAISKELSEITTAEA HHHHHHHHHHCCCCC	28.22	22633953
502	Phosphorylation	VPRGGFDSPFYRDSL CCCCCCCCCCCCCCC	18.04	25521595
505	Phosphorylation	GGFDSPFYRDSLSGS CCCCCCCCCCCCCCC	19.52	26643407
508	Phosphorylation	DSPFYRDSLSGSQRK CCCCCCCCCCCCCCC	18.55	26643407
510	Phosphorylation	PFYRDSLSGSQRKTH CCCCCCCCCCCCCCC	40.11	25338131
512	Phosphorylation	YRDSLSGSQRKTHSA CCCCCCCCCCCCCCC	24.36	30352176
516	Phosphorylation	LSGSQRKTHSAASGT CCCCCCCCCCCCCCC	24.21	26643407
518	Phosphorylation	GSQRKTHSAASGTQG CCCCCCCCCCCCCCC	30.66	30352176
521	Phosphorylation	RKTHSAASGTQGSSV CCCCCCCCCCCCCCC	41.93	24899341
523	Phosphorylation	THSAASGTQGSSVNP CCCCCCCCCCCCCCC	27.54	29550500
526	Phosphorylation	AASGTQGSSVNPEPL CCCCCCCCCCCCCCC	22.69	29550500
527	Phosphorylation	ASGTQGSSVNPEPLH CCCCCCCCCCCCCCC	32.51	27681418
535	Phosphorylation	VNPEPLHSSLDKHGP CCCCCCCCCHHCCCC	40.03	26643407
536	Phosphorylation	NPEPLHSSLDKHGPD CCCCCCCCHHCCCCC	29.82	26643407
544	Phosphorylation	LDKHGPDTPKQAFTP HHCCCCCCCCCCCCC	35.20	29899451
550	Phosphorylation	DTPKQAFTPIDPPSG CCCCCCCCCCCCCCC	23.50	30635358
556	Phosphorylation	FTPIDPPSGSADVSP CCCCCCCCCCCCCCC	51.25	21183079
558	Phosphorylation	PIDPPSGSADVSPAG CCCCCCCCCCCCCCC	26.15	28066266
562	Phosphorylation	PSGSADVSPAGDRDR CCCCCCCCCCCCCCC	15.02	25521595
572	Phosphorylation	GDRDRQTSLETSILT CCCCCCCCCEEECCC	18.83	29899451
575	Phosphorylation	DRQTSLETSILTPSP CCCCCCEEECCCCCC	26.76	29899451
576	Phosphorylation	RQTSLETSILTPSPC CCCCCEEECCCCCCC	13.26	29472430
579	Phosphorylation	SLETSILTPSPCKIP CCEEECCCCCCCCCC	21.76	29472430
581	Phosphorylation	ETSILTPSPCKIPPQ EEECCCCCCCCCCCC	37.38	29899451
592	Phosphorylation	IPPQRGVSFGSGQLP CCCCCCCCCCCCCCC	27.06	26824392
595	Phosphorylation	QRGVSFGSGQLPPYD CCCCCCCCCCCCCCC	22.73	21183079
601	Phosphorylation	GSGQLPPYDHLFEVA CCCCCCCCCHHHHHH	17.66	23984901
639	Phosphorylation	PEEDCVPSTSPMEVL CHHHCCCCCCHHHHH	22.56	29899451
641	Phosphorylation	EDCVPSTSPMEVLDR HHCCCCCCHHHHHHH	26.96	29899451
662	Phosphorylation	GAHSKELSRLSLPSK CCCCHHHHHCCCCCC	32.06	29472430
664 (in isoform 3)	Phosphorylation	-	5.76	29514104
665	Phosphorylation	SKELSRLSLPSKSVD CHHHHHCCCCCCCCC	36.80	25266776
668	Phosphorylation	LSRLSLPSKSVDWTH HHHCCCCCCCCCCCC	42.74	24759943
669 (in isoform 3)	Phosphorylation	-	53.19	29899451
670	Phosphorylation	RLSLPSKSVDWTHFG HCCCCCCCCCCCCCC	29.64	29899451
679	Phosphorylation	DWTHFGGSPPSDELR CCCCCCCCCCHHHHH	33.73	22817900
911	Phosphorylation	RRVLELESLLAKKDH HHHHHHHHHHHHCCH	41.11	25619855
1032	Phosphorylation	ASCGGRVTGGSSSSS CCCCCCCCCCCCCCC	34.17	25619855
1035	Phosphorylation	GGRVTGGSSSSSSEL CCCCCCCCCCCCCCC	28.52	25619855
1036	Phosphorylation	GRVTGGSSSSSSELS CCCCCCCCCCCCCCC	37.20	25619855
1037	Phosphorylation	RVTGGSSSSSSELST CCCCCCCCCCCCCCC	35.62	25619855
1038	Phosphorylation	VTGGSSSSSSELSTP CCCCCCCCCCCCCCC	39.57	25619855
1039	Phosphorylation	TGGSSSSSSELSTPE CCCCCCCCCCCCCCC	29.76	25619855
1040	Phosphorylation	GGSSSSSSELSTPEK CCCCCCCCCCCCCCC	44.50	25619855
1043	Phosphorylation	SSSSSELSTPEKPPS CCCCCCCCCCCCCCH	37.55	25619855
1044	Phosphorylation	SSSSELSTPEKPPSQ CCCCCCCCCCCCCHH	48.36	25619855
1050	Phosphorylation	STPEKPPSQRFSSRW CCCCCCCHHHCCCCC	42.38	25619855
1065	Phosphorylation	EPALGEPSSSIPTTV CCCCCCCCCCCCCCC	32.20	25619855
1066	Phosphorylation	PALGEPSSSIPTTVG CCCCCCCCCCCCCCC	42.90	25619855
1067	Phosphorylation	ALGEPSSSIPTTVGS CCCCCCCCCCCCCCC	36.60	25619855
1070	Phosphorylation	EPSSSIPTTVGSLPS CCCCCCCCCCCCCCC	32.23	25619855
1071	Phosphorylation	PSSSIPTTVGSLPSS CCCCCCCCCCCCCCC	19.95	25619855
1074	Phosphorylation	SIPTTVGSLPSSKSF CCCCCCCCCCCCCHH	32.54	22942356
1077	Phosphorylation	TTVGSLPSSKSFLGM CCCCCCCCCCHHHCH	56.54	25619855
1078	Phosphorylation	TVGSLPSSKSFLGMK CCCCCCCCCHHHCHH	30.31	25619855
1080	Phosphorylation	GSLPSSKSFLGMKAR CCCCCCCHHHCHHHH	27.87	22324799
1094	Phosphorylation	RELFRNKSESQCDED HHHHHCCCHHHCCCC	46.13	25619855
1096	Phosphorylation	LFRNKSESQCDEDSV HHHCCCHHHCCCCCC	43.11	25619855
1102	Phosphorylation	ESQCDEDSVTMSSSS HHHCCCCCCCCCHHH	19.89	25619855
1104	Phosphorylation	QCDEDSVTMSSSSLS HCCCCCCCCCHHHHH	18.45	29899451
1128	Phosphorylation	DSGTENKTSLSLDAP CCCCCCCCEEEEECC	46.62	26643407
1129	Phosphorylation	SGTENKTSLSLDAPH CCCCCCCEEEEECCC	19.98	26643407
1131	Phosphorylation	TENKTSLSLDAPHPS CCCCCEEEEECCCCC	24.78	26643407
1138	Phosphorylation	SLDAPHPSSPNSDNV EEECCCCCCCCCCCC	56.23	26643407
1139	Phosphorylation	LDAPHPSSPNSDNVG EECCCCCCCCCCCCC	32.33	26643407
1142	Phosphorylation	PHPSSPNSDNVGQLH CCCCCCCCCCCCEEE	33.67	26643407
1153	Phosphorylation	GQLHIMDYNETHPEH CEEEEEECCCCCCCC	9.49	26643407
1156	Phosphorylation	HIMDYNETHPEHS-- EEEECCCCCCCCC--	38.81	26643407

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TSC1_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
502	S	Phosphorylation		21183079
Phosphorylation at Ser-502 does not affect interaction with TSC2.

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TSC1_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RADI_MOUSE	Rdx	physical	10806479
EZRI_MOUSE	Ezr	physical	10806479
EZRI_HUMAN	EZR	physical	10806479
MOES_MOUSE	Msn	physical	10806479
BEX3_MOUSE	Ngfrap1	physical	17355907
DC1I2_HUMAN	DYNC1I2	physical	26496610
DYN2_HUMAN	DNM2	physical	26496610
JAK1_HUMAN	JAK1	physical	26496610
PYGB_HUMAN	PYGB	physical	26496610
SFPQ_HUMAN	SFPQ	physical	26496610
TSC2_HUMAN	TSC2	physical	26496610
ZNF3_HUMAN	ZNF3	physical	26496610
RT29_HUMAN	DAP3	physical	26496610
SLU7_HUMAN	SLU7	physical	26496610
LTMD1_HUMAN	LETMD1	physical	26496610
TBCD7_HUMAN	TBC1D7	physical	26496610
CCAR1_HUMAN	CCAR1	physical	26496610
4ET_HUMAN	EIF4ENIF1	physical	26496610
ANO3_HUMAN	ANO3	physical	26496610
DEFM_HUMAN	PDF	physical	26496610
RT09_HUMAN	MRPS9	physical	26496610
SGF29_HUMAN	CCDC101	physical	26496610
ZBED6_HUMAN	ZBED6	physical	26496610
KCC2A_MOUSE	Camk2a	physical	28671696
CDK5_MOUSE	Cdk5	physical	28671696
CNRP1_MOUSE	Cnrip1	physical	28671696
CTNB1_MOUSE	Ctnnb1	physical	28671696
CUL3_MOUSE	Cul3	physical	28671696
CYFP2_MOUSE	Cyfip2	physical	28671696
DNJA1_MOUSE	Dnaja1	physical	28671696
DNJA2_MOUSE	Dnaja2	physical	28671696
DNJA4_MOUSE	Dnaja4	physical	28671696
FA49B_MOUSE	Fam49b	physical	28671696
FBX41_MOUSE	Fbxo41	physical	28671696
RACK1_MOUSE	Gnb2l1	physical	28671696
RASH_MOUSE	Hras	physical	28671696
RASK_MOUSE	Kras	physical	28671696
LGI1_MOUSE	Lgi1	physical	28671696
KPCB_MOUSE	Prkcb	physical	28671696
KPCG_MOUSE	Prkcg	physical	28671696
PURA_MOUSE	Pura	physical	28671696
RAB14_MOUSE	Rab14	physical	28671696
RAB7A_MOUSE	Rab7	physical	28671696
RAC1_MOUSE	Rac1	physical	28671696
RAN_MOUSE	Ran	physical	28671696
RAP2B_MOUSE	Rap2b	physical	28671696
RASL1_MOUSE	Rasal1	physical	28671696
SC23A_MOUSE	Sec23a	physical	28671696
TBCD7_MOUSE	Tbc1d7	physical	28671696
TNIK_MOUSE	Tnik	physical	28671696
TENR_MOUSE	Tnr	physical	28671696
TRIM3_MOUSE	Trim3	physical	28671696
WASF1_MOUSE	Wasf1	physical	28671696
1433Z_MOUSE	Ywhaz	physical	28671696
ABI1_MOUSE	Abi1	physical	28671696
DP13A_MOUSE	Appl1	physical	28671696
RHG32_MOUSE	Arhgap32	physical	28671696
ARHG2_MOUSE	Arhgef2	physical	28671696
KCC2B_MOUSE	Camk2b	physical	28671696
KCC2D_MOUSE	Camk2d	physical	28671696
KCC2G_MOUSE	Camk2g	physical	28671696
CYFP1_MOUSE	Cyfip1	physical	28671696
DLG4_MOUSE	Dlg4	physical	28671696
MINK1_MOUSE	Mink1	physical	28671696
NCKP1_MOUSE	Nckap1	physical	28671696
PP2BA_MOUSE	Ppp3ca	physical	28671696
SHAN3_MOUSE	Shank3	physical	28671696
SYGP1_MOUSE	Syngap1	physical	28671696
AMPD2_MOUSE	Ampd2	physical	28671696
PYR1_MOUSE	Cad	physical	28671696
TCPG_MOUSE	Cct3	physical	28671696
TCPQ_MOUSE	Cct8	physical	28671696
CLAP1_MOUSE	Clasp1	physical	28671696
DCX_MOUSE	Dcx	physical	28671696
DYR1A_MOUSE	Dyrk1a	physical	28671696
EF2_MOUSE	Eef2	physical	28671696
IF4A2_MOUSE	Eif4a2	physical	28671696
EPHA4_MOUSE	Epha4	physical	28671696
TCAF1_MOUSE	Fam115a	physical	28671696
FOXG1_MOUSE	Foxg1	physical	28671696
FXR1_MOUSE	Fxr1	physical	28671696
HS90A_MOUSE	Hsp90aa1	physical	28671696
HS90B_MOUSE	Hsp90ab1	physical	28671696
HSP7C_MOUSE	Hspa8	physical	28671696
MPRI_MOUSE	Igf2r	physical	28671696
KDM1A_MOUSE	Kdm1a	physical	28671696
KIF5C_MOUSE	Kif5c	physical	28671696
LTOR1_MOUSE	Lamtor1	physical	28671696
MAGD1_MOUSE	Maged1	physical	28671696
MATR3_MOUSE	Matr3	physical	28671696
NCAN_MOUSE	Ncan	physical	28671696
NEDD4_MOUSE	Nedd4	physical	28671696
NISCH_MOUSE	Nisch	physical	28671696
PAK5_MOUSE	Pak7	physical	28671696
PP2AB_MOUSE	Ppp2cb	physical	28671696
PTPRS_MOUSE	Ptprs	physical	28671696
SCRIB_MOUSE	Scrib	physical	28671696
SESD1_MOUSE	Sestd1	physical	28671696
SFPQ_MOUSE	Sfpq	physical	28671696
SMC2_MOUSE	Smc2	physical	28671696
SOGA3_MOUSE	Soga3	physical	28671696
TDRD3_MOUSE	Tdrd3	physical	28671696
TMEDA_MOUSE	Tmed10	physical	28671696
TMED9_MOUSE	Tmed9	physical	28671696
TNKS1_MOUSE	Tnks	physical	28671696
TP53B_MOUSE	Trp53bp1	physical	28671696
TIF1B_MOUSE	Trim28	physical	28671696
USP9X_MOUSE	Usp9x	physical	28671696
WNK2_MOUSE	Wnk2	physical	28671696
WNK3_MOUSE	Wnk3	physical	28671696
1433T_MOUSE	Ywhaq	physical	28671696

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TSC1_MOUSE

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Qualitative and quantitative analyses of protein phosphorylation innaive and stimulated mouse synaptosomal preparations."; Munton R.P., Tweedie-Cullen R., Livingstone-Zatchej M., Weinandy F.,Waidelich M., Longo D., Gehrig P., Potthast F., Rutishauser D.,Gerrits B., Panse C., Schlapbach R., Mansuy I.M.; Mol. Cell. Proteomics 6:283-293(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-394, AND MASSSPECTROMETRY.	17114649 [Abstract]

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