DNJA4_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DNJA4_MOUSE
• UniProt AC: Q9JMC3
• Protein Name: DnaJ homolog subfamily A member 4
• Gene Name: Dnaja4
• Organism: Mus musculus (Mouse).
• Sequence Length: 397
• Subcellular Localization: Membrane ; Lipid-anchor .
• Protein Sequence: MVKETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEGEKFKLISQAYEVLSDPKKRDIYDQGGEQAIKEGGSGSPSFSSPMDIFDMFFGGGGRMTRERRGKNVVHQLSVTLEDLYNGITKKLALQKNVICEKCEGIGGKKGSVEKCPLCKGRGMQVHIQQIGPGMVQQIQTVCIECKGQGERINPKDRCENCSGAKVTREKKIIEVHVEKGMKDGQKILFHGEGDQEPELDPGDVIIVLDQKDHSVFQRRGQDLIMKMKIQLSEALCGFKKTIKTLDDRVLVISSKSGEVIKHGDLKCIRNEGMPIYKAPLEKGVMIIQFLVVFPEKQWLSQEKLPQLEALLPPRQKVRITDDMDQVELKEFNPNEQSWRQHREAYEEDDEEPRAGVQCQTA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Phosphorylation	DILGVKPSASPEEIK EECCCCCCCCHHHHH	35.34	27742792
18	Phosphorylation	LGVKPSASPEEIKKA CCCCCCCCHHHHHHH	36.86	27742792
32	Ubiquitination	AYRKLALKYHPDKNP HHHHHHHHHCCCCCC	35.59	22790023
64	Phosphorylation	DPKKRDIYDQGGEQA CCCCCCCCCCCHHHH	13.40	-
77	Phosphorylation	QAIKEGGSGSPSFSS HHHHCCCCCCCCCCC	47.13	27180971
79	Phosphorylation	IKEGGSGSPSFSSPM HHCCCCCCCCCCCCC	21.04	23737553
81	Phosphorylation	EGGSGSPSFSSPMDI CCCCCCCCCCCCCHH	39.18	23737553
83	Phosphorylation	GSGSPSFSSPMDIFD CCCCCCCCCCCHHHH	37.56	25293948
84	Phosphorylation	SGSPSFSSPMDIFDM CCCCCCCCCCHHHHH	23.41	25293948
113	Phosphorylation	KNVVHQLSVTLEDLY CCCEEEEECCHHHHH	13.39	29899451
144	Acetylation	KCEGIGGKKGSVEKC ECCCCCCCCCCCCCC	49.07	19856023
190	Ubiquitination	GQGERINPKDRCENC CCCCCCCCCCCCCCC	37.24	27667366
313	Ubiquitination	NEGMPIYKAPLEKGV CCCCCCEECCHHHCE	44.22	22790023
336	Phosphorylation	FPEKQWLSQEKLPQL CCHHHCCCCCCCCHH	33.08	28542873
373	Phosphorylation	EFNPNEQSWRQHREA HCCCCHHHHHHHHHH	20.32	23684622
394	Farnesylation	EPRAGVQCQTA---- CCCCCCCCCCC----	3.45	-
394	Methylation	EPRAGVQCQTA---- CCCCCCCCCCC----	3.45	-
471	Ubiquitination	--------------------------------------------------------------------------------- ---------------------------------------------------------------------------------		27667366

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DNJA4_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DNJA4_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DNJA4_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of DNJA4_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.