| UniProt ID | CE152_HUMAN | |
|---|---|---|
| UniProt AC | O94986 | |
| Protein Name | Centrosomal protein of 152 kDa | |
| Gene Name | CEP152 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 1710 | |
| Subcellular Localization | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Colocalizes with CDK5RAP2, WDR62 and CEP63 in a discrete ring around the proximal end of the parental | |
| Protein Description | Necessary for centrosome duplication; the function seems also to involve CEP63, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. [PubMed: 26297806 Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 molecules involved in centriole formation] | |
| Protein Sequence | MSLDFGSVALPVQNEDEEYDEEDYEREKELQQLLTDLPHDMLDDDLSSPELQYSDCSEDGTDGQPHHPEQLEMSWNEQMLPKSQSVNGYNEIQSLYAGEKCGNVWEENRSKTEDRHPVYHPEEGGDEGGSGYSPPSKCEQTDLYHLPENFRPYTNGQKQEFNNQATNVIKFSDPQWNHFQGPSCQGLEPYNKVTYKPYQSSAQNNGSPAQEITGSDTFEGLQQQFLGANENSAENMQIIQLQVLNKAKERQLENLIEKLNESERQIRYLNHQLVIIKDEKDGLTLSLRESQKLFQNGKEREIQLEAQIKALETQIQALKVNEEQMIKKSRTTEMALESLKQQLVDLHHSESLQRAREQHESIVMGLTKKYEEQVLSLQKNLDATVTALKEQEDICSRLKDHVKQLERNQEAIKLEKTEIINKLTRSLEESQKQCAHLLQSGSVQEVAQLQFQLQQAQKAHAMSANMNKALQEELTELKDEISLYESAAKLGIHPSDSEGELNIELTESYVDLGIKKVNWKKSKVTSIVQEEDPNEELSKDEFILKLKAEVQRLLGSNSMKRHLVSQLQNDLKDCHKKIEDLHQVKKDEKSIEVETKTDTSEKPKNQLWPESSTSDVVRDDILLLKNEIQVLQQQNQELKETEGKLRNTNQDLCNQMRQMVQDFDHDKQEAVDRCERTYQQHHEAMKTQIRESLLAKHALEKQQLFEAYERTHLQLRSELDKLNKEVTAVQECYLEVCREKDNLELTLRKTTEKEQQTQEKIKEKLIQQLEKEWQSKLDQTIKAMKKKTLDCGSQTDQVTTSDVISKKEMAIMIEEQKCTIQQNLEQEKDIAIKGAMKKLEIELELKHCENITKQVEIAVQNAHQRWLGELPELAEYQALVKAEQKKWEEQHEVSVNKRISFAVSEAKEKWKSELENMRKNILPGKELEEKIHSLQKELELKNEEVPVVIRAELAKARSEWNKEKQEEIHRIQEQNEQDYRQFLDDHRNKINEVLAAAKEDFMKQKTELLLQKETELQTCLDQSRREWTMQEAKRIQLEIYQYEEDILTVLGVLLSDTQKEHISDSEDKQLLEIMSTCSSKWMSVQYFEKLKGCIQKAFQDTLPLLVENADPEWKKRNMAELSKDSASQGTGQGDPGPAAGHHAQPLALQATEAEADKKKVLEIKDLCCGHCFQELEKAKQECQDLKGKLEKCCRHLQHLERKHKAVVEKIGEENNKVVEELIEENNDMKNKLEELQTLCKTPPRSLSAGAIENACLPCSGGALEELRGQYIKAVKKIKCDMLRYIQESKERAAEMVKAEVLRERQETARKMRKYYLICLQQILQDDGKEGAEKKIMNAASKLATMAKLLETPISSKSQSKTTQSALPLTSEMLIAVKKSKRNDVNQKIPCCIESKSNSVNTITRTLCEQAPKRRAACNLQRLLENSEHQSIKHVGSKETHLEFQFGDGSCKHLNSLPRNVSPEFVPCEGEGGFGLHKKKDLLSDNGSESLPHSAAYPFLGTLGNKPSPRCTPGPSESGCMHITFRDSNERLGLKVYKCNPLMESENAASEKSQGLDVQEPPVKDGGDLSDCLGWPSSSATLSFDSREASFVHGRPQGTLEIPSESVKSKQFSPSGYLSDTEESNMICQTMKCQRYQTPYLSEETTYLEPGKISVNCGHPSRHKADRLKSDFKKLSSTLPSSVCQQPSRKLIVPLSSQQDSGFDSPFVNLD | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MSLDFGSVA ------CCCCCCCCE | 48.20 | - | |
| 24 | Phosphorylation | EEYDEEDYEREKELQ CCCCHHHHHHHHHHH | 21.84 | - | |
| 83 | Phosphorylation | NEQMLPKSQSVNGYN CCCCCCHHHCCCCHH | 26.25 | 28450419 | |
| 85 | Phosphorylation | QMLPKSQSVNGYNEI CCCCHHHCCCCHHHH | 25.33 | 28450419 | |
| 89 | Phosphorylation | KSQSVNGYNEIQSLY HHHCCCCHHHHHHHH | 12.38 | 28450419 | |
| 119 | Phosphorylation | TEDRHPVYHPEEGGD CCCCCCCCCCCCCCC | 18.99 | 20873877 | |
| 130 | Phosphorylation | EGGDEGGSGYSPPSK CCCCCCCCCCCCCHH | 45.47 | 23663014 | |
| 132 | Phosphorylation | GDEGGSGYSPPSKCE CCCCCCCCCCCHHCC | 21.50 | 23663014 | |
| 133 | Phosphorylation | DEGGSGYSPPSKCEQ CCCCCCCCCCHHCCC | 33.58 | 23663014 | |
| 136 | Phosphorylation | GSGYSPPSKCEQTDL CCCCCCCHHCCCCCC | 54.01 | 30576142 | |
| 144 | Phosphorylation | KCEQTDLYHLPENFR HCCCCCCCCCCCCCC | 12.24 | - | |
| 190 | Phosphorylation | SCQGLEPYNKVTYKP CCCCCCCCCCCCCCC | 20.45 | 27642862 | |
| 268 | Phosphorylation | ESERQIRYLNHQLVI HHHHHHHHHCCCEEE | 17.31 | 26126808 | |
| 286 | Phosphorylation | EKDGLTLSLRESQKL CCCCEEEEHHHHHHH | 21.83 | 24719451 | |
| 349 | Phosphorylation | QLVDLHHSESLQRAR HHHHHHHHHHHHHHH | 20.38 | 20873877 | |
| 351 | Phosphorylation | VDLHHSESLQRAREQ HHHHHHHHHHHHHHH | 32.58 | 20873877 | |
| 367 | Phosphorylation | ESIVMGLTKKYEEQV HHHHHHHCHHHHHHH | 21.54 | - | |
| 370 | Phosphorylation | VMGLTKKYEEQVLSL HHHHCHHHHHHHHHH | 26.67 | 24114839 | |
| 376 | Phosphorylation | KYEEQVLSLQKNLDA HHHHHHHHHHHHHHH | 29.87 | 24719451 | |
| 384 | Phosphorylation | LQKNLDATVTALKEQ HHHHHHHHHHHHHHH | 20.32 | 24114839 | |
| 413 | Ubiquitination | ERNQEAIKLEKTEII HHHHHHHHHHHHHHH | 58.61 | - | |
| 417 | Phosphorylation | EAIKLEKTEIINKLT HHHHHHHHHHHHHHH | 24.04 | 19664994 | |
| 422 | Ubiquitination | EKTEIINKLTRSLEE HHHHHHHHHHHCHHH | 40.61 | - | |
| 432 | Ubiquitination | RSLEESQKQCAHLLQ HCHHHHHHHHHHHHH | 57.53 | - | |
| 484 | Phosphorylation | LKDEISLYESAAKLG HHHHHHHHHHHHHHC | 10.88 | 27642862 | |
| 495 | Phosphorylation | AKLGIHPSDSEGELN HHHCCCCCCCCCCCC | 39.34 | 26074081 | |
| 497 | Phosphorylation | LGIHPSDSEGELNIE HCCCCCCCCCCCCEE | 52.41 | 26074081 | |
| 506 | Phosphorylation | GELNIELTESYVDLG CCCCEEEEHHHHHCC | 15.30 | - | |
| 522 | Phosphorylation | KKVNWKKSKVTSIVQ CCCCCCHHHCEEEEC | 28.73 | - | |
| 523 | Ubiquitination | KVNWKKSKVTSIVQE CCCCCHHHCEEEECC | 59.41 | - | |
| 525 | Phosphorylation | NWKKSKVTSIVQEED CCCHHHCEEEECCCC | 19.24 | 25159151 | |
| 526 | Phosphorylation | WKKSKVTSIVQEEDP CCHHHCEEEECCCCC | 24.61 | 25159151 | |
| 539 | Ubiquitination | DPNEELSKDEFILKL CCCCCCCCCHHHHHH | 74.11 | - | |
| 547 | Ubiquitination | DEFILKLKAEVQRLL CHHHHHHHHHHHHHH | 40.70 | - | |
| 556 | Phosphorylation | EVQRLLGSNSMKRHL HHHHHHCCCHHHHHH | 26.21 | 20068231 | |
| 558 | Phosphorylation | QRLLGSNSMKRHLVS HHHHCCCHHHHHHHH | 27.64 | 20068231 | |
| 560 | Ubiquitination | LLGSNSMKRHLVSQL HHCCCHHHHHHHHHH | 36.16 | - | |
| 577 | Ubiquitination | DLKDCHKKIEDLHQV HHHHHHHHHHHHHHH | 27.88 | - | |
| 590 | Phosphorylation | QVKKDEKSIEVETKT HHHCCCCCCEEEECC | 23.18 | 23401153 | |
| 595 | Phosphorylation | EKSIEVETKTDTSEK CCCCEEEECCCCCCC | 44.41 | 26471730 | |
| 596 | Ubiquitination | KSIEVETKTDTSEKP CCCEEEECCCCCCCC | 30.78 | - | |
| 597 | Phosphorylation | SIEVETKTDTSEKPK CCEEEECCCCCCCCH | 52.51 | 28302921 | |
| 599 | Phosphorylation | EVETKTDTSEKPKNQ EEEECCCCCCCCHHH | 43.98 | 25002506 | |
| 600 | Phosphorylation | VETKTDTSEKPKNQL EEECCCCCCCCHHHC | 46.57 | 25002506 | |
| 612 | Phosphorylation | NQLWPESSTSDVVRD HHCCCCCCCCHHHHH | 30.21 | 30576142 | |
| 613 | Phosphorylation | QLWPESSTSDVVRDD HCCCCCCCCHHHHHH | 37.92 | 30576142 | |
| 614 | Phosphorylation | LWPESSTSDVVRDDI CCCCCCCCHHHHHHH | 30.29 | 30576142 | |
| 644 | Ubiquitination | ELKETEGKLRNTNQD HHHHHHHHHHHCCHH | 37.73 | - | |
| 677 | Phosphorylation | AVDRCERTYQQHHEA HHHHHHHHHHHHHHH | 11.91 | - | |
| 678 | Phosphorylation | VDRCERTYQQHHEAM HHHHHHHHHHHHHHH | 16.64 | - | |
| 686 | Ubiquitination | QQHHEAMKTQIRESL HHHHHHHHHHHHHHH | 44.30 | - | |
| 701 | Ubiquitination | LAKHALEKQQLFEAY HHHHHHHHHHHHHHH | 44.16 | - | |
| 740 | Ubiquitination | YLEVCREKDNLELTL HHHHHHHHCCEEEEE | 32.34 | - | |
| 771 | Ubiquitination | KLIQQLEKEWQSKLD HHHHHHHHHHHHHHH | 73.22 | - | |
| 776 | Ubiquitination | LEKEWQSKLDQTIKA HHHHHHHHHHHHHHH | 40.77 | - | |
| 782 | Ubiquitination | SKLDQTIKAMKKKTL HHHHHHHHHHHHCCC | 45.90 | - | |
| 786 | Ubiquitination | QTIKAMKKKTLDCGS HHHHHHHHCCCCCCC | 37.59 | - | |
| 787 | Ubiquitination | TIKAMKKKTLDCGSQ HHHHHHHCCCCCCCC | 49.12 | - | |
| 805 | Phosphorylation | VTTSDVISKKEMAIM CCHHHHCCHHHHHHH | 37.21 | - | |
| 807 | Acetylation | TSDVISKKEMAIMIE HHHHCCHHHHHHHHH | 46.03 | 27452117 | |
| 807 | Ubiquitination | TSDVISKKEMAIMIE HHHHCCHHHHHHHHH | 46.03 | - | |
| 828 | Ubiquitination | QQNLEQEKDIAIKGA HHCHHHHHHHHHHHH | 54.88 | - | |
| 833 | Ubiquitination | QEKDIAIKGAMKKLE HHHHHHHHHHHHHHH | 31.43 | - | |
| 853 | Ubiquitination | KHCENITKQVEIAVQ HHHCCHHHHHHHHHH | 48.85 | - | |
| 881 | Ubiquitination | AEYQALVKAEQKKWE HHHHHHHHHHHHHHH | 47.24 | - | |
| 897 | Acetylation | QHEVSVNKRISFAVS HHCCCHHHHHHHHHH | 49.29 | 25953088 | |
| 897 | Ubiquitination | QHEVSVNKRISFAVS HHCCCHHHHHHHHHH | 49.29 | - | |
| 900 | Phosphorylation | VSVNKRISFAVSEAK CCHHHHHHHHHHHHH | 15.93 | 30266825 | |
| 907 | Ubiquitination | SFAVSEAKEKWKSEL HHHHHHHHHHHHHHH | 56.63 | - | |
| 909 | Ubiquitination | AVSEAKEKWKSELEN HHHHHHHHHHHHHHH | 60.25 | - | |
| 919 | Ubiquitination | SELENMRKNILPGKE HHHHHHHHHCCCCHH | 37.26 | - | |
| 925 | Ubiquitination | RKNILPGKELEEKIH HHHCCCCHHHHHHHH | 58.13 | - | |
| 930 | Ubiquitination | PGKELEEKIHSLQKE CCHHHHHHHHHHHHH | 36.02 | - | |
| 933 | Phosphorylation | ELEEKIHSLQKELEL HHHHHHHHHHHHHCC | 35.65 | 21857030 | |
| 936 | Ubiquitination | EKIHSLQKELELKNE HHHHHHHHHHCCCCC | 70.34 | - | |
| 941 | Ubiquitination | LQKELELKNEEVPVV HHHHHCCCCCCCCEE | 53.60 | - | |
| 989 | Ubiquitination | FLDDHRNKINEVLAA HHHHHHHHHHHHHHH | 47.03 | - | |
| 998 | Ubiquitination | NEVLAAAKEDFMKQK HHHHHHHHHHHHHHH | 53.76 | - | |
| 998 (in isoform 3) | Ubiquitination | - | 53.76 | - | |
| 1005 | Ubiquitination | KEDFMKQKTELLLQK HHHHHHHHHHHHHHH | 38.15 | - | |
| 1006 | Phosphorylation | EDFMKQKTELLLQKE HHHHHHHHHHHHHHH | 29.39 | - | |
| 1012 | Ubiquitination | KTELLLQKETELQTC HHHHHHHHHHHHHHH | 67.58 | - | |
| 1028 | O-linked_Glycosylation | DQSRREWTMQEAKRI HHHHHHHHHHHHHHH | 12.29 | 30379171 | |
| 1033 | Ubiquitination | EWTMQEAKRIQLEIY HHHHHHHHHHCCEEE | 49.64 | - | |
| 1063 | O-linked_Glycosylation | DTQKEHISDSEDKQL CCCHHHCCCHHHHHH | 36.67 | 30379171 | |
| 1063 | Phosphorylation | DTQKEHISDSEDKQL CCCHHHCCCHHHHHH | 36.67 | 22210691 | |
| 1065 | O-linked_Glycosylation | QKEHISDSEDKQLLE CHHHCCCHHHHHHHH | 40.69 | 30379171 | |
| 1065 | Phosphorylation | QKEHISDSEDKQLLE CHHHCCCHHHHHHHH | 40.69 | 22210691 | |
| 1068 | Ubiquitination | HISDSEDKQLLEIMS HCCCHHHHHHHHHHH | 38.50 | - | |
| 1089 | Ubiquitination | MSVQYFEKLKGCIQK HHHHHHHHHHHHHHH | 45.67 | - | |
| 1101 | Phosphorylation | IQKAFQDTLPLLVEN HHHHHHHHHHHHHCC | 21.35 | - | |
| 1114 | Ubiquitination | ENADPEWKKRNMAEL CCCCHHHHHHCHHHH | 39.95 | - | |
| 1114 (in isoform 3) | Ubiquitination | - | 39.95 | - | |
| 1115 | Ubiquitination | NADPEWKKRNMAELS CCCHHHHHHCHHHHC | 50.51 | - | |
| 1115 (in isoform 3) | Ubiquitination | - | 50.51 | - | |
| 1157 | Ubiquitination | ATEAEADKKKVLEIK HCHHHHHHHHHHHHH | 73.48 | - | |
| 1158 | Ubiquitination | TEAEADKKKVLEIKD CHHHHHHHHHHHHHH | 45.16 | - | |
| 1159 | Ubiquitination | EAEADKKKVLEIKDL HHHHHHHHHHHHHHH | 41.60 | - | |
| 1164 | Ubiquitination | KKKVLEIKDLCCGHC HHHHHHHHHHHCHHH | 43.36 | - | |
| 1237 | Phosphorylation | NKLEELQTLCKTPPR HHHHHHHHHHCCCCC | 16.19 | 30266825 | |
| 1240 | Ubiquitination | EELQTLCKTPPRSLS HHHHHHHCCCCCCCC | 3.91 | - | |
| 1241 | Phosphorylation | ELQTLCKTPPRSLSA HHHHHHCCCCCCCCC | 37.20 | 23401153 | |
| 1245 | Phosphorylation | LCKTPPRSLSAGAIE HHCCCCCCCCCCCCC | 3.37 | 30108239 | |
| 1247 | Phosphorylation | KTPPRSLSAGAIENA CCCCCCCCCCCCCCC | 55.33 | 30108239 | |
| 1259 | Phosphorylation | ENACLPCSGGALEEL CCCEECCCCCHHHHH | 7.82 | 22210691 | |
| 1272 | Acetylation | ELRGQYIKAVKKIKC HHHHHHHHHHHHCCC | 61.03 | 20167786 | |
| 1272 | Ubiquitination | ELRGQYIKAVKKIKC HHHHHHHHHHHHCCC | 61.03 | - | |
| 1276 | Acetylation | QYIKAVKKIKCDMLR HHHHHHHHCCCHHHH | 66.78 | 20167786 | |
| 1278 | Acetylation | IKAVKKIKCDMLRYI HHHHHHCCCHHHHHH | 38.40 | 20167786 | |
| 1278 | Ubiquitination | IKAVKKIKCDMLRYI HHHHHHCCCHHHHHH | 38.40 | - | |
| 1285 (in isoform 3) | Ubiquitination | - | 37.10 | - | |
| 1297 | Ubiquitination | ERAAEMVKAEVLRER HHHHHHHHHHHHHHH | 10.69 | - | |
| 1314 | Phosphorylation | TARKMRKYYLICLQQ HHHHHHHHHHHHHHH | 28.79 | - | |
| 1315 | Phosphorylation | ARKMRKYYLICLQQI HHHHHHHHHHHHHHH | 32.54 | 18083107 | |
| 1321 (in isoform 3) | Ubiquitination | - | 42.16 | - | |
| 1333 | Ubiquitination | DGKEGAEKKIMNAAS CCCHHHHHHHHHHHH | 17.60 | - | |
| 1334 | Ubiquitination | GKEGAEKKIMNAASK CCHHHHHHHHHHHHH | 4.09 | - | |
| 1339 (in isoform 3) | Ubiquitination | - | 40.65 | - | |
| 1341 | Acetylation | KIMNAASKLATMAKL HHHHHHHHHHHHHHH | 54.43 | 25953088 | |
| 1341 | Ubiquitination | KIMNAASKLATMAKL HHHHHHHHHHHHHHH | 54.43 | - | |
| 1347 | Ubiquitination | SKLATMAKLLETPIS HHHHHHHHHHCCCCC | 18.63 | - | |
| 1351 | Phosphorylation | TMAKLLETPISSKSQ HHHHHHCCCCCCCCC | 3.44 | 30266825 | |
| 1354 | Phosphorylation | KLLETPISSKSQSKT HHHCCCCCCCCCCCC | 6.84 | 30266825 | |
| 1355 | Phosphorylation | LLETPISSKSQSKTT HHCCCCCCCCCCCCC | 30.31 | 30266825 | |
| 1356 | Ubiquitination | LETPISSKSQSKTTQ HCCCCCCCCCCCCCH | 58.49 | - | |
| 1360 | Ubiquitination | ISSKSQSKTTQSALP CCCCCCCCCCHHCCC | 4.86 | - | |
| 1377 | Ubiquitination | SEMLIAVKKSKRNDV HHHHHHHHHHHCCCC | 27.74 | - | |
| 1387 | Ubiquitination | KRNDVNQKIPCCIES HCCCCCCCCCCCCCC | 10.31 | - | |
| 1395 | Ubiquitination | IPCCIESKSNSVNTI CCCCCCCCCCCHHHH | 53.47 | - | |
| 1396 | Phosphorylation | PCCIESKSNSVNTIT CCCCCCCCCCHHHHH | 34.27 | 26471730 | |
| 1398 | Phosphorylation | CIESKSNSVNTITRT CCCCCCCCHHHHHHH | 41.02 | 26471730 | |
| 1405 | Phosphorylation | SVNTITRTLCEQAPK CHHHHHHHHHHHCCH | 23.43 | 18669648 | |
| 1412 | Ubiquitination | TLCEQAPKRRAACNL HHHHHCCHHHHHHHH | 54.96 | - | |
| 1426 | Phosphorylation | LQRLLENSEHQSIKH HHHHHHCCCCCCCCC | 9.66 | - | |
| 1430 | Phosphorylation | LENSEHQSIKHVGSK HHCCCCCCCCCCCCC | 37.47 | 28122231 | |
| 1432 | Ubiquitination | NSEHQSIKHVGSKET CCCCCCCCCCCCCCC | 58.66 | - | |
| 1437 | Ubiquitination | SIKHVGSKETHLEFQ CCCCCCCCCCEEEEE | 16.80 | - | |
| 1449 | Phosphorylation | EFQFGDGSCKHLNSL EEECCCCCCCCCCCC | 45.11 | 26074081 | |
| 1451 | Ubiquitination | QFGDGSCKHLNSLPR ECCCCCCCCCCCCCC | 26.96 | - | |
| 1455 | Phosphorylation | GSCKHLNSLPRNVSP CCCCCCCCCCCCCCC | 32.34 | 28555341 | |
| 1461 | Phosphorylation | NSLPRNVSPEFVPCE CCCCCCCCCCCCCCC | 41.45 | 29255136 | |
| 1478 | Ubiquitination | GGFGLHKKKDLLSDN CCCCCCCCCCCCCCC | 41.54 | - | |
| 1479 | Ubiquitination | GFGLHKKKDLLSDNG CCCCCCCCCCCCCCC | 7.12 | - | |
| 1483 | Phosphorylation | HKKKDLLSDNGSESL CCCCCCCCCCCCCCC | 28.70 | 28961369 | |
| 1487 | Phosphorylation | DLLSDNGSESLPHSA CCCCCCCCCCCCCCC | 63.68 | 28348404 | |
| 1489 | Phosphorylation | LSDNGSESLPHSAAY CCCCCCCCCCCCCHH | 37.27 | 28348404 | |
| 1493 | Phosphorylation | GSESLPHSAAYPFLG CCCCCCCCCHHCCCC | 43.05 | 28961369 | |
| 1496 | Phosphorylation | SLPHSAAYPFLGTLG CCCCCCHHCCCCCCC | 25.98 | 26074081 | |
| 1501 | Phosphorylation | AAYPFLGTLGNKPSP CHHCCCCCCCCCCCC | 9.26 | 20873877 | |
| 1505 | Ubiquitination | FLGTLGNKPSPRCTP CCCCCCCCCCCCCCC | 45.07 | - | |
| 1507 | Phosphorylation | GTLGNKPSPRCTPGP CCCCCCCCCCCCCCC | 57.33 | 20873877 | |
| 1511 | Phosphorylation | NKPSPRCTPGPSESG CCCCCCCCCCCCCCC | 48.83 | 26074081 | |
| 1515 | Phosphorylation | PRCTPGPSESGCMHI CCCCCCCCCCCEEEE | 3.21 | 26074081 | |
| 1534 | Ubiquitination | SNERLGLKVYKCNPL CCCCEECEEEECCHH | 6.40 | - | |
| 1537 | Ubiquitination | RLGLKVYKCNPLMES CEECEEEECCHHHCC | 37.35 | - | |
| 1552 | Phosphorylation | ENAASEKSQGLDVQE CCHHHHHHCCCCCCC | 29.54 | 29255136 | |
| 1589 | Phosphorylation | SFDSREASFVHGRPQ EECCCCCEECCCCCC | 29.41 | 28122231 | |
| 1598 | Phosphorylation | VHGRPQGTLEIPSES CCCCCCCEEECCHHH | 8.60 | 27251275 | |
| 1607 | Ubiquitination | EIPSESVKSKQFSPS ECCHHHHCCCCCCCC | 51.37 | - | |
| 1609 | Ubiquitination | PSESVKSKQFSPSGY CHHHHCCCCCCCCCC | 62.34 | - | |
| 1612 | Phosphorylation | SVKSKQFSPSGYLSD HHCCCCCCCCCCCCC | 49.20 | 27251275 | |
| 1614 | Phosphorylation | KSKQFSPSGYLSDTE CCCCCCCCCCCCCCH | 58.77 | 28450419 | |
| 1616 | Phosphorylation | KQFSPSGYLSDTEES CCCCCCCCCCCCHHH | 58.77 | 28450419 | |
| 1618 | Phosphorylation | FSPSGYLSDTEESNM CCCCCCCCCCHHHCC | 5.15 | 28450419 | |
| 1620 | Phosphorylation | PSGYLSDTEESNMIC CCCCCCCCHHHCCHH | 44.38 | 28450419 | |
| 1623 | Phosphorylation | YLSDTEESNMICQTM CCCCCHHHCCHHHHH | 25.33 | 30108239 | |
| 1631 | Ubiquitination | NMICQTMKCQRYQTP CCHHHHHCCCCCCCC | 37.40 | - | |
| 1644 | Phosphorylation | TPYLSEETTYLEPGK CCCCCCCCCEECCCE | 36.70 | 21945579 | |
| 1645 | Phosphorylation | PYLSEETTYLEPGKI CCCCCCCCEECCCEE | 38.37 | 21945579 | |
| 1646 | Phosphorylation | YLSEETTYLEPGKIS CCCCCCCEECCCEEE | 11.00 | 21945579 | |
| 1651 | Ubiquitination | TTYLEPGKISVNCGH CCEECCCEEEEECCC | 8.69 | - | |
| 1669 | Phosphorylation | HKADRLKSDFKKLSS HHHHHHHHHHHHHHC | 30631047 | ||
| 1673 | Ubiquitination | RLKSDFKKLSSTLPS HHHHHHHHHHCCCCH | - | ||
| 1676 | Phosphorylation | SDFKKLSSTLPSSVC HHHHHHHCCCCHHHH | 30631047 | ||
| 1680 | Phosphorylation | KLSSTLPSSVCQQPS HHHCCCCHHHHCCCC | 30631047 | ||
| 1681 | Phosphorylation | LSSTLPSSVCQQPSR HHCCCCHHHHCCCCC | 30631047 | ||
| 1689 | Ubiquitination | VCQQPSRKLIVPLSS HHCCCCCEEEEECCC | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CE152_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CE152_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CE152_HUMAN !! | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1405, AND MASSSPECTROMETRY. | |
| "An extensive survey of tyrosine phosphorylation revealing new sitesin human mammary epithelial cells."; Heibeck T.H., Ding S.-J., Opresko L.K., Zhao R., Schepmoes A.A.,Yang F., Tolmachev A.V., Monroe M.E., Camp D.G. II, Smith R.D.,Wiley H.S., Qian W.-J.; J. Proteome Res. 8:3852-3861(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-1258, AND MASSSPECTROMETRY. | |
