RTL9_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RTL9_HUMAN
• UniProt AC: Q8NET4
• Protein Name: Retrotransposon Gag-like protein 9 {ECO:0000312|HGNC:HGNC:29245}
• Gene Name: RTL9 {ECO:0000312|HGNC:HGNC:29245}
• Organism: Homo sapiens (Human).
• Sequence Length: 1388
• Protein Sequence: MSIPLHSLRFNNTMREENVEPQNKQMAFCRPMTETRADVQILHSHVQLPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPSFGMLTPALCYLLEEQEAARGSCSVEEEMEIDEEKQMKGFLDDSERMAFLVSLHLGAAERWFILQMEVGEPLSHENKSFLRRSQGIYDSLSEIDILSAVLCHPKQGQKSVRQYATDFLLLARHLSWSDAILRTRFLEGLSEAVTTKMGRIFLKVAGSLKELIDRSLYTECQLAEEKDSPGNSSQVLPTACKRNNEEAMGNELSSQQQTEEHQHVSKRCYYLKEHGDPQEGLHDHLGQSTGHHQKAHTNK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MSIPLHSLRFNNTM -CCCCHHHHCCCCCC		-
412	Phosphorylation	ALDSGAMSTPLMGAP ECCCCCCCCCCCCCC		-
413	Phosphorylation	LDSGAMSTPLMGAPA CCCCCCCCCCCCCCC		-
430	Phosphorylation	NMSTLQKTVPASGAM CCCCCCCEECCCCCE		-
434	Phosphorylation	LQKTVPASGAMTTSL CCCEECCCCCEEEEE		26503892
439	Phosphorylation	PASGAMTTSLMTVPS CCCCCEEEEEEECCC		26503892
464	Phosphorylation	ATASRVMSAQLTMAK HHHHHHHHHHHHHHH		23532336
468	Phosphorylation	RVMSAQLTMAKTSGA HHHHHHHHHHHHCCC		24719451
473	Phosphorylation	QLTMAKTSGAMPTGS HHHHHHHCCCCCCCH		23532336
478	Phosphorylation	KTSGAMPTGSMKAVA HHCCCCCCCHHHHHH		24719451
494	Phosphorylation	QYKRATASGKMSTPL HHHHHHCCCCCCCCC		25332170
498	Phosphorylation	ATASGKMSTPLRRAP HHCCCCCCCCCCCCC		24719451
499	Phosphorylation	TASGKMSTPLRRAPT HCCCCCCCCCCCCCC		22210691
512	Phosphorylation	PTSGAMSTQPVTATA CCCCCCCCCCEEEEC		22210691
550	Phosphorylation	APVSEAMSMPQMRTM CCHHHHHCCHHHHHH		-
556	Phosphorylation	MSMPQMRTMASGLTS HCCHHHHHHHHCCCH		-
572	Phosphorylation	AQMKAMTSGAMSTPL HHHHHHHCCCCCCCC		18669648
577	Phosphorylation	MTSGAMSTPLMTAQT HHCCCCCCCCEEEEC		23532336
581	Phosphorylation	AMSTPLMTAQTSGST CCCCCCEEEECCCCC		23532336
588	Phosphorylation	TAQTSGSTSTLLMRD EEECCCCCCEEEEEC		18669648
602	Phosphorylation	DTASGVMSCPQMRSL CCCCCCCCCHHHHHH		23532336
608	Phosphorylation	MSCPQMRSLASGALS CCCHHHHHHHHCCCC		27542207
611	Phosphorylation	PQMRSLASGALSKPL HHHHHHHHCCCCCCC		27542207
615	Phosphorylation	SLASGALSKPLMTPK HHHHCCCCCCCCCCC		24719451
620	Phosphorylation	ALSKPLMTPKASGTM CCCCCCCCCCCCCCC		20446291
624	Phosphorylation	PLMTPKASGTMFTEK CCCCCCCCCCCCEEC		20446291
626	Phosphorylation	MTPKASGTMFTEKMT CCCCCCCCCCEECEE		24719451
629	Phosphorylation	KASGTMFTEKMTTTA CCCCCCCEECEECCH		20446291
633	Phosphorylation	TMFTEKMTTTASEAM CCCEECEECCHHHHC		30243723
634	Phosphorylation	MFTEKMTTTASEAMP CCEECEECCHHHHCC		30243723
635	Phosphorylation	FTEKMTTTASEAMPT CEECEECCHHHHCCC		30243723
637	Phosphorylation	EKMTTTASEAMPTLL ECEECCHHHHCCCHH		30243723
642	Phosphorylation	TASEAMPTLLMRDTV CHHHHCCCHHHHCCC		20393185
676	Phosphorylation	SLMRDTASGAMSTSQ HHHHHCCCCCCCCCC		-
685	Phosphorylation	AMSTSQMTATVSGGM CCCCCCEEEEEECCC		22210691
689	Phosphorylation	SQMTATVSGGMSMPL CCEEEEEECCCCCCC		22210691
693	Phosphorylation	ATVSGGMSMPLMRAQ EEEECCCCCCCEECC		22210691
715	Phosphorylation	SLMRAKVSGKMLSQP HHHHHHHCCCCCCCC		24719451
734	Phosphorylation	DPGGMSMSPMKSMTA CCCCCCCCCCCCCCC		-
748	Phosphorylation	AGGMQMNSPTSDVMS CCCCCCCCCCCCCCC		28985074
750	Phosphorylation	GMQMNSPTSDVMSTP CCCCCCCCCCCCCCC		23403867
751	Phosphorylation	MQMNSPTSDVMSTPT CCCCCCCCCCCCCCC		28985074
758	Phosphorylation	SDVMSTPTVRAWTSE CCCCCCCCHHCCCCC		-
774	Phosphorylation	MSTPLMRTSDPGERP CCCCCCCCCCCCCCC		23403867
775	Phosphorylation	STPLMRTSDPGERPS CCCCCCCCCCCCCCC		23403867
782	Phosphorylation	SDPGERPSLLTRASS CCCCCCCCHHHCCCC		24719451
842	Phosphorylation	PQVKAPISGAMSMPL CCCCCCCCCCCCCCC		30576142
872	Phosphorylation	APDSRVTSTSQMMPT CCCCCCCCCCCCCCC		-
874	Phosphorylation	DSRVTSTSQMMPTAS CCCCCCCCCCCCCCC		22468782
879	Phosphorylation	STSQMMPTASGDMCT CCCCCCCCCCCCCCC		22468782
881	Phosphorylation	SQMMPTASGDMCTLP CCCCCCCCCCCCCCC		22468782
886	Phosphorylation	TASGDMCTLPVRAPA CCCCCCCCCCEECCC		-
911	Phosphorylation	APASGTMSTPLRRPS CCCCCCCCCCCCCCC		24719451
931	Phosphorylation	STELMRASASGHMST CHHHHHHHHCCCCCC		23322592
933	Phosphorylation	ELMRASASGHMSTAQ HHHHHHHCCCCCCHH		23322592
937	Phosphorylation	ASASGHMSTAQTTAM HHHCCCCCCHHHHHH		25278378
938	Phosphorylation	SASGHMSTAQTTAMV HHCCCCCCHHHHHHH		25278378
941	Phosphorylation	GHMSTAQTTAMVSGG CCCCCHHHHHHHCCC		25278378
942	Phosphorylation	HMSTAQTTAMVSGGM CCCCHHHHHHHCCCC		25278378
950	Phosphorylation	AMVSGGMSKPLMRAP HHHCCCCCCCCCCCC		24719451
959	Phosphorylation	PLMRAPASGTMPMPL CCCCCCCCCCCCHHH		-
1022	Phosphorylation	ATAPIRASASGARST ECCCEEECCCCCCCC		-
1024	Phosphorylation	APIRASASGARSTSF CCEEECCCCCCCCCC		-
1035	Phosphorylation	STSFMRASVSGSMPM CCCCEECCCCCCCCC		28270605
1037	Phosphorylation	SFMRASVSGSMPMPL CCEECCCCCCCCCCC		28270605
1039	Phosphorylation	MRASVSGSMPMPLPR EECCCCCCCCCCCCC		22210691
1062	Phosphorylation	GMSMPQMTATDSRGM CCCCCCCCCCCCCCC		28985074
1066	Phosphorylation	PQMTATDSRGMSTPL CCCCCCCCCCCCCCC		22210691
1070	Phosphorylation	ATDSRGMSTPLMRAS CCCCCCCCCCCCCCC		22210691
1081	Phosphorylation	MRASGPGTMSTPQTA CCCCCCCCCCCCCEE		28985074
1084	Phosphorylation	SGPGTMSTPQTAFGV CCCCCCCCCCEECCC		-
1094	Phosphorylation	TAFGVMSTPEIKATD EECCCCCCCCEEECC		28985074
1191	Phosphorylation	ERMAFLVSLHLGAAE HHHHHHHHHHHCHHH		24719451
1217	Phosphorylation	PLSHENKSFLRRSQG CCCCCCHHHHHHHCC		24719451
1248	Phosphorylation	HPKQGQKSVRQYATD CCCCCCHHHHHHHHH		18187866
1271	Methylation	SWSDAILRTRFLEGL CHHHHHHHHHHHHHH		54561729
1271	Dimethylation	SWSDAILRTRFLEGL CHHHHHHHHHHHHHH		-
1304	Phosphorylation	LKELIDRSLYTECQL HHHHHHHHHHHHHHH		27461979
1306	Phosphorylation	ELIDRSLYTECQLAE HHHHHHHHHHHHHHH		27461979
1307	Phosphorylation	LIDRSLYTECQLAEE HHHHHHHHHHHHHHH		27461979
1317	Phosphorylation	QLAEEKDSPGNSSQV HHHHHCCCCCCCCHH		27461979
1321	Phosphorylation	EKDSPGNSSQVLPTA HCCCCCCCCHHHCHH		27461979
1322	Phosphorylation	KDSPGNSSQVLPTAC CCCCCCCCHHHCHHH		27461979
1327	Phosphorylation	NSSQVLPTACKRNNE CCCHHHCHHHHHCCH		27461979

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RTL9_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RTL9_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RTL9_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HSF1_HUMAN	HSF1	physical	27173435

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.