| UniProt ID | PRP17_YEAST | |
|---|---|---|
| UniProt AC | P40968 | |
| Protein Name | Pre-mRNA-processing factor 17 | |
| Gene Name | CDC40 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 455 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | May function in the second step of pre-mRNA splicing. Regulatory protein involved in replication and mitotic spindle formation and/or maintenance. Required for initiation and completion of S-phase and for initiation and completion of DNA replication. Might be required for the maintenance of microtubules. Essential only at elevated temperatures.. | |
| Protein Sequence | MGLVDGYDTSSDSDLNFDEGKSVHEKKNGNLHEDTSYEPSSNNIHKRKSHFTKSELKRRRKTRKGDGPWGSWSSSDDETSQASETQKEDQDIFVHALAEDNLDSEQIEVEEVSHFYGKSEKDYQGRGYLYPPNDVDVDLREERISFRCYLPKKVIRNYPGHPEGTTALKFLPKTGHLILSGGNDHTIKIWDFYHDYECLRDFQGHNKPIKALRFTEDCQSFLSSSFDRSVKIWDTETGKVKTRLHLNSTPADVESRPTNPHEFIVGLSNSKILHYDDRVSENQGLVQTYDHHLSSILALKYFPDGSKFISSSEDKTVRIWENQINVPIKQISDTAQHSMPFLNVHPSQNYFCAQSMDNRIYSFSLKPKYKRHPKKIFKGHSSAGYGISLAFSGDGRYICSGDSKSRLFTWDWNTSRLLNNIKIPGNKPITQVDWHPQETSKVICSGAAGKIYVCD | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 7 | Phosphorylation | -MGLVDGYDTSSDSD -CCCCCCCCCCCCCC | 16.16 | 19795423 | |
| 9 | Phosphorylation | GLVDGYDTSSDSDLN CCCCCCCCCCCCCCC | 22.96 | 19795423 | |
| 10 | Phosphorylation | LVDGYDTSSDSDLNF CCCCCCCCCCCCCCC | 29.29 | 19795423 | |
| 11 | Phosphorylation | VDGYDTSSDSDLNFD CCCCCCCCCCCCCCC | 43.13 | 19795423 | |
| 13 | Phosphorylation | GYDTSSDSDLNFDEG CCCCCCCCCCCCCCC | 46.04 | 19795423 | |
| 41 | Phosphorylation | DTSYEPSSNNIHKRK CCCCCCCCCCCCCCC | 44.61 | 27017623 | |
| 46 | Acetylation | PSSNNIHKRKSHFTK CCCCCCCCCCCCCCH | 58.69 | 25381059 | |
| 158 | Phosphorylation | PKKVIRNYPGHPEGT CHHHHHCCCCCCCCC | 10.76 | 28889911 | |
| 165 | Phosphorylation | YPGHPEGTTALKFLP CCCCCCCCCCCCCCC | 13.77 | 19779198 | |
| 248 | Phosphorylation | KTRLHLNSTPADVES EEEEECCCCCCCCCC | 41.97 | 19779198 | |
| 268 | Phosphorylation | HEFIVGLSNSKILHY CCEEEEECCCEEEEC | 32.88 | 19779198 | |
| 270 | Phosphorylation | FIVGLSNSKILHYDD EEEEECCCEEEECCC | 20.07 | 19779198 | |
| 382 | Phosphorylation | KIFKGHSSAGYGISL CEECCCCCCCCCEEE | 21.75 | 19779198 | |
| 388 | Phosphorylation | SSAGYGISLAFSGDG CCCCCCEEEEEECCC | 14.85 | 19779198 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PRP17_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PRP17_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PRP17_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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