dbPTM

DJ1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DJ1_SCHPO
UniProt AC	Q10356
Protein Name	Glutathione-independent glyoxalase DJ-1 {ECO:0000303\|PubMed:24758716}
Gene Name	hsp3106 {ECO:0000312\|PomBase:SPAC22E12.03c}
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	191
Subcellular Localization	Cytoplasm . Nucleus .
Protein Description	Catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step. [PubMed: 24758716 May play a role in detoxifying endogenously produced glyoxals. Involved in protection against reactive oxygen species (ROS) (By similarity]
Protein Sequence	MVKVCLFVADGTDEIEFSAPWGIFKRAEIPIDSVYVGENKDRLVKMSRDVEMYANRSYKEIPSADDFAKQYDIAIIPGGGLGAKTLSTTPFVQQVVKEFYKKPNKWIGMICAGTLTAKTSGLPNKQITGHPSVRGQLEEGGYKYLDQPVVLEENLITSQGPGTAMLFGLKLLEQVASKDKYNAVYKSLSMP

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of DJ1_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DJ1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DJ1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DJ1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ACAC_SCHPO	cut6	physical	26152728
ADH_SCHPO	adh1	physical	26152728
ARO1_SCHPO	aro1	physical	26152728
AROG_SCHPO	SPAP8A3.07c	physical	26152728
ASSY_SCHPO	arg12	physical	26152728
ATPA_SCHPO	atp1	physical	26152728
BFR1_SCHPO	bfr1	physical	26152728
CARB_SCHPO	arg4	physical	26152728
CDC48_SCHPO	cdc48	physical	26152728
GDH2_SCHPO	gdh2	physical	26152728
EBP2_SCHPO	ebp2	physical	26152728
EFTU_SCHPO	tuf1	physical	26152728
ERF3_SCHPO	sup35	physical	26152728
FAS2_SCHPO	fas2	physical	26152728
FBRL_SCHPO	fib1	physical	26152728
G3P2_SCHPO	gpd3	physical	26152728
GAR1_SCHPO	gar1	physical	26152728
GLT1_SCHPO	glt1	physical	26152728
GLY1_SCHPO	gly1	physical	26152728
GPD1_SCHPO	gpd1	physical	26152728
GRP78_SCHPO	bip1	physical	26152728
HMT2_SCHPO	hmt2	physical	26152728
HOSM_SCHPO	lys4	physical	26152728
HSP16_SCHPO	hsp16	physical	26152728
HSP7F_SCHPO	pss1	physical	26152728
HXK1_SCHPO	hxk1	physical	26152728
IDHP_SCHPO	idp1	physical	26152728
PFKA_SCHPO	pfk1	physical	26152728
KPR2_SCHPO	SPCC1620.06c	physical	26152728
LCF1_SCHPO	lcf1	physical	26152728
LEU3_SCHPO	leu1	physical	26152728
MAS5_SCHPO	mas5	physical	26152728
MET10_SCHPO	SPCC584.01c	physical	26152728
MPCP_SCHPO	SPBC1703.13c	physical	26152728
MPG1_SCHPO	mpg1	physical	26152728
NDH2_SCHPO	nde1	physical	26152728
NOP10_SCHPO	nop10	physical	26152728
NOP56_SCHPO	SPBC646.10c	physical	26152728
NOP58_SCHPO	SPAC23G3.06	physical	26152728
PDC4_SCHPO	SPAC3G9.11c	physical	26152728
PMP20_SCHPO	pmp20	physical	26152728
PRS10_SCHPO	rpt4	physical	26152728
PRS6A_SCHPO	rpt5	physical	26152728
PRS8_SCHPO	rpt6	physical	26152728
PUR6_SCHPO	ade6	physical	26152728
PYC_SCHPO	pyr1	physical	26152728
PYR1_SCHPO	ura1	physical	26152728
RAD25_SCHPO	rad25	physical	26152728
RHO1_SCHPO	rho1	physical	26152728
RL14_SCHPO	rpl14	physical	26152728
RL15B_SCHPO	rpl1502	physical	26152728
RL17A_SCHPO	rpl1701	physical	26152728
RL18A_SCHPO	rpl1801	physical	26152728
RL18B_SCHPO	rpl1802	physical	26152728
RL21A_SCHPO	rpl2101	physical	26152728
RL24B_SCHPO	rpl2402	physical	26152728
RL25A_SCHPO	rpl2501	physical	26152728
RL25B_SCHPO	rpl2502	physical	26152728
RL26_SCHPO	rpl26	physical	26152728
RL27A_SCHPO	rpl2701	physical	26152728
RL27B_SCHPO	rpl2702	physical	26152728
RL28A_SCHPO	rpl2802	physical	26152728
RL29_SCHPO	rpl29	physical	26152728
RL30B_SCHPO	rpl3002	physical	26152728
RL31_SCHPO	rpl31	physical	26152728
RL32A_SCHPO	rpl3202	physical	26152728
RL33B_SCHPO	rpl35a	physical	26152728
RL35_SCHPO	rpl35	physical	26152728
RL36B_SCHPO	rpl3602	physical	26152728
RL3B_SCHPO	rpl302	physical	26152728
RL43A_SCHPO	rpl4301	physical	26152728
RL4A_SCHPO	rpl402	physical	26152728
RL4B_SCHPO	rpl401	physical	26152728
RL5B_SCHPO	rpl502	physical	26152728
RL6_SCHPO	rpl6	physical	26152728
RL7B_SCHPO	rpl702	physical	26152728
RL7C_SCHPO	rpl701	physical	26152728
RL8_SCHPO	rpl8	physical	26152728
RL9A_SCHPO	rpl901	physical	26152728
RL9B_SCHPO	rpl902	physical	26152728
RNC1_SCHPO	rnc1	physical	26152728
RPIA_SCHPO	SPAC144.12	physical	26152728
RRP5_SCHPO	SPCC1183.07	physical	26152728
RS13_SCHPO	rps13	physical	26152728
RS15A_SCHPO	rps1501	physical	26152728
RS15B_SCHPO	rps1502	physical	26152728
RS17B_SCHPO	rps1702	physical	26152728
RS19A_SCHPO	rps1901	physical	26152728
RS24A_SCHPO	rps2401	physical	26152728
RS25A_SCHPO	rps2502	physical	26152728
RS26B_SCHPO	rps2602	physical	26152728
RS2_SCHPO	rps2	physical	26152728
RS3A1_SCHPO	rps101	physical	26152728
RS3A2_SCHPO	rps102	physical	26152728
RS3_SCHPO	rps3	physical	26152728
RS4B_SCHPO	rps402	physical	26152728
RS4C_SCHPO	rps403	physical	26152728
RS5B_SCHPO	rps502	physical	26152728
RS6B_SCHPO	rps602	physical	26152728
RS7_SCHPO	rps7	physical	26152728
RS8B_SCHPO	rps802	physical	26152728
RS9B_SCHPO	rps902	physical	26152728
RUVB2_SCHPO	rvb2	physical	26152728
PIL1_SCHPO	pil1	physical	26152728
SPI1_SCHPO	spi1	physical	26152728
SRP68_SCHPO	srp68	physical	26152728
SUCB_SCHPO	SPCC1620.08	physical	26152728
SYEC_SCHPO	gus1	physical	26152728
SYG_SCHPO	grs1	physical	26152728
SYMC_SCHPO	rar1	physical	26152728
TBB_SCHPO	nda3	physical	26152728
TCG1_SCHPO	tcg1	physical	26152728
THI4_SCHPO	thi2	physical	26152728
THI6_SCHPO	thi4	physical	26152728
TOM70_SCHPO	tom70	physical	26152728
TRXB_SCHPO	trr1	physical	26152728
YAY1_SCHPO	SPAC4H3.01	physical	26152728
YBP8_SCHPO	SPBC16H5.08c	physical	26152728
YCO6_SCHPO	nap1	physical	26152728
DJ1_SCHPO	hsp3106	physical	26152728
YDMC_SCHPO	SPAC57A7.12	physical	26152728
YEAF_SCHPO	SPACUNK4.15	physical	26152728
YEG9_SCHPO	SPAC26H5.09c	physical	26152728
YFG5_SCHPO	SPAC19G12.05	physical	26152728
YFM8_SCHPO	SPAC222.08c	physical	26152728
YG23_SCHPO	sac11	physical	26152728
YIW2_SCHPO	SPAC694.02	physical	26152728
YL8C_SCHPO	SPAC25B8.12c	physical	26152728
YLI2_SCHPO	SPAC458.02c	physical	26152728
YPT1_SCHPO	ypt1	physical	26152728
RL22_SCHPO	rpl22	physical	26152728

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DJ1_SCHPO

Related Literatures of Post-Translational Modification