dbPTM

YDMC_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YDMC_SCHPO
UniProt AC	P87142
Protein Name	Heat shock protein 70 homolog C57A7.12
Gene Name	SPAC57A7.12
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	566
Subcellular Localization
Protein Description
Protein Sequence	MQLKLTKTLPFSENFIMADSEEYKTVIGISFGNQNSSIAFNRDGKTDVLANEEGNRQIPSILSYHGDQEYHGVQARGQLVRNADNSVTNFRDLLGKSHDELTLHHCHYSANPVNVEGQIGFKITVQEDEESDPKEKILTAHEASVRHLRRLTESAEDFLGTKVNGCVMSVPVYFTDAQRKALESAANEAGLPVLQLIHDPAAVILALMYSEEVLIDKTVVVANFGATRSEVSVVSVKGGLMTILASVHDENLGGEQLTDVLVNFFAKEFEKKNGIDPRKNARSLAKLRAQCEITKRVLSNGTTASAAVDSLADGIDFHSSINRLRYDLAASATLNRMADLVTEAVEKANMEPFDISEVILAGGASNTPKLTSLMESIFPEQTIIRSSSSVTPLQLDPSELTAIGSGVQASLIGHFDAADIAASTDAQVVDVPHLTAPIGINEGENFVTIFDIETALPARKTVEVIAPKEGAAFIPIYEAERSVKVTKVEPEPIDEEEAFSDDEEEEPEEIKERIAIPKTLIATITLPDVSPNAKIELVLQIDAEGKLTASARPKDGKGTNVRGSTA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Phosphorylation	LTKTLPFSENFIMAD EEEECCCCCCEEECC	29.68	21712547
20	Phosphorylation	ENFIMADSEEYKTVI CCEEECCCHHHEEEE	23.84	21712547
86	Phosphorylation	LVRNADNSVTNFRDL EEECCCCCCCCHHHH	30.76	28889911
88	Phosphorylation	RNADNSVTNFRDLLG ECCCCCCCCHHHHHC	28.58	25720772
131	Phosphorylation	TVQEDEESDPKEKIL EEECCCCCCHHHHHH	58.11	25720772
500	Phosphorylation	IDEEEAFSDDEEEEP CCHHHCCCCCCCCCH	51.72	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YDMC_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YDMC_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YDMC_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YDMC_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YDMC_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-86 AND SER-500, AND MASSSPECTROMETRY.	18257517 [Abstract]