dbPTM

YG23_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YG23_SCHPO
UniProt AC	O60162
Protein Name	Uncharacterized protein C19F5.03
Gene Name	SPBC19F5.03
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	598
Subcellular Localization	Endoplasmic reticulum membrane Multi-pass membrane protein .
Protein Description
Protein Sequence	MVQFEANEKQFKLRREDCCLTIDRESGAVSFEPDELKPVARSKENSVTLFGSIKLKKDKYLILATEKSSAAQILGHKIYRVHKFEVIPYRNLLADDQDELDLYNLLQNHLKTGPFYFSYTWDLTNSLQRSCTDEGKASPILRSDKRFFWNEFASKDFIDLIGAHSEVSLFITPMIYGFITSASTIVKGRTITLALISRRSKQRAGTRYFTRGLDENGNPANFNETEQITIVSDEKSEVTYSHVQTRGSVPAFWAEVNNLRYKPLMVANSASMAAAAAKKHFDEQISIYGDQVVVNLVNCKGHELPIKQLYENVIRRLDNPHIHYHYFDFHKECSHMRWDRVSLLLNEIQPELEEQGYTTLDTQKYRVLSRQNGVVRSNCMDCLDRTNVVQSCIGRWVLTNQLRKCGIIGATHPLRSVIPLDNIFCNIWSDNADYISLSYSGTGALKTDFTRTGIRTRKGAFNDFVNSAKRYILNNFYDGARQDAYDLVLGQFRPDVNFRYRLDLRPLTIRCVPYILLACLILFFMTLFSRSSSTILPPSILLILTFLGIVASLYYCFAHGLQFINWPRLLLPSFLRSDMTPEGRVFVINRQLASKHKV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
42	Phosphorylation	ELKPVARSKENSVTL HCCCCCCCCCCCEEE	34.29	25720772
46	Phosphorylation	VARSKENSVTLFGSI CCCCCCCCEEEEEEE	19.99	28889911
68	Phosphorylation	LILATEKSSAAQILG EEEEECCCCHHHHHC	20.98	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YG23_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YG23_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YG23_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YG23_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YG23_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-46, AND MASSSPECTROMETRY.	18257517 [Abstract]