dbPTM

EBP2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	EBP2_SCHPO
UniProt AC	O13802
Protein Name	Probable rRNA-processing protein ebp2
Gene Name	ebp2
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	333
Subcellular Localization	Nucleus, nucleolus .
Protein Description	Required for the processing of the 27S pre-rRNA..
Protein Sequence	MAGIESKQRRAQKKAAKAAMKEKKNKESNESSTSVEALNEKEMINTIKSPIIETADTADQENESEGSDEVELSDLEGIELEEDADLIRKRKLAINNTVALENIYERIKYPDDISFVENQAVTTKEPIIIENVEDDLARELAFYKQGVSSVKAAFAKLREANVLISRPHDYFAEMLKSDDHMEKVRQELIKEATAKKLSQQAKKQRELKKFGKQVQLAKQEERQREKKETLEKINLLKRKHTGGDLTTEDDFDIALSSASADTFKKGSRSTKSRPQPNPKRQKKNEKYGFGGPKHRSKSNDLDSLAATEFGRKGLKNIKSKKRPGKARREKARK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
28	Phosphorylation	KEKKNKESNESSTSV HHHCCCCCCCCCCHH	47.72	21712547
31	Phosphorylation	KNKESNESSTSVEAL CCCCCCCCCCHHHHH	43.07	24763107
33	Phosphorylation	KESNESSTSVEALNE CCCCCCCCHHHHHCH	46.18	29996109
34	Phosphorylation	ESNESSTSVEALNEK CCCCCCCHHHHHCHH	21.65	24763107
272	Phosphorylation	KGSRSTKSRPQPNPK CCCCCCCCCCCCCCC	49.64	28889911
296	Phosphorylation	FGGPKHRSKSNDLDS CCCCCCCCCCCCHHH	39.91	29996109
298	Phosphorylation	GPKHRSKSNDLDSLA CCCCCCCCCCHHHHH	36.50	28889911
303	Phosphorylation	SKSNDLDSLAATEFG CCCCCHHHHHHHHHH	27.49	24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of EBP2_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of EBP2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of EBP2_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of EBP2_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of EBP2_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-272, AND MASSSPECTROMETRY.	18257517 [Abstract]