dbPTM

SYG_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SYG_SCHPO
UniProt AC	Q10179
Protein Name	Putative glycine--tRNA ligase
Gene Name	grs1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	652
Subcellular Localization	Cytoplasm .
Protein Description	Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs (By similarity)..
Protein Sequence	MTEVSKAAAFDRTQFEELMKKRFFFSPSFQIYGGISGLYDYGPPGSALQSNLVDIWRKHFVIEESMLEVDCSMLTPHEVLKTSGHVDKFADWMCKDPATGEIFRADHLVEEVLEARLKGDKEARGQNSNDQPEESDDKKKRKKKVKEIRATRLDDKTVEEYEFILAQIDNYDGDQLGELMKKYDIRNPATNGELETPRQFNLMFETQIGPSGGLKGYLRPETAQGQFLNFSRLLEFNNGKVPFASAMVGKAFRNEISPRSGLLRVREFLMAEVEHFVDPKNKEHDRFDEVSHMPLRLLPRGVQLEGKTDILEMPIGDAVKKGIVDNTTLGYFMARISLFLEKIGIDMNRVRFRQHMSNEMAHYACDCWDAEIQCSYGWIECVGCADRSAYDLSVHSKATKTPLVVQEALPEPVVVEQFEVEVNRKKFGPRFKRDAKAVEEAMISWPESEKVEKSAQLVAEGKIIVNVNGVEHTVESDLVTIEKRKHTEHIRTYTPNVIEPSFGLGRILYVLMEHAYWTRPEDVNRGVLSFPASIAPIKALIVPLSRNAEFAPFVKKLSAKLRNLGISNKIDDSNANIGRRYARNDELGTPFGLTVDFETLQNETITLRERDSTKQVRGSQDEVIAALVSMVEGKSSFEDALAKFGEFKSTQE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
492	Phosphorylation	KHTEHIRTYTPNVIE CCCCHHHHCCCCCEE	31.01	25720772
493	Phosphorylation	HTEHIRTYTPNVIEP CCCHHHHCCCCCEEC	15.45	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SYG_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SYG_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SYG_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of SYG_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SYG_SCHPO

Related Literatures of Post-Translational Modification