dbPTM

YL8C_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YL8C_SCHPO
UniProt AC	Q9UTA6
Protein Name	Uncharacterized hydrolase C25B8.12c
Gene Name	SPAC25B8.12c
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	303
Subcellular Localization	Cytoplasm . Nucleus .
Protein Description
Protein Sequence	MSAVDKTNNLPTLDTLQMVISDVDGTLLDKHHRFHFRTYRAMKYIREKYPNFPIVLATGKQRSAVDLIRIPLDLDAFPAAHVNGCVLYNKGKIVYADHLKPEVVMEVVEATKGNPNIANVVYDEHYVYALTPGREDMKNVKRLAEIGEKVDFSMPCEEAIEKVKSGEIKVIKMAVCEDPDKLDVVRDILGKFPREKFATTQALEFCIELIPSNSNKGTALQYITSNILPEVKNENVISFGDGQNDLSMFAIAGWSVAIKNGMPIAIEKAKAVSRVGNEEGAVGEVLERIFNIPEDYTPPPYTF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
63	Phosphorylation	LATGKQRSAVDLIRI EECCCCCCCCCEEEE	30.10	28889911
218	Phosphorylation	PSNSNKGTALQYITS CCCCCCCCHHHHHHH	26.29	25720772
225	Phosphorylation	TALQYITSNILPEVK CHHHHHHHCCCHHHC	16.59	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YL8C_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YL8C_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YL8C_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YL8C_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YL8C_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-63, AND MASSSPECTROMETRY.	18257517 [Abstract]