dbPTM

RL18A_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RL18A_SCHPO
UniProt AC	Q10192
Protein Name	60S ribosomal protein L18-A
Gene Name	rpl1801
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	187
Subcellular Localization
Protein Description
Protein Sequence	MGIDIERHHVKKSQRSKPASENVYLKLLVKLYRFLARRTDSRFNKAILKRLFQSKTNRPPISISKIAALTSRKSASSQNKTTVVVGTVTDDERMLTVPKLSIAALRFTKSARARILKAGGEVLTLDQLALRAPTGSNTVLVRGKKHAREAYRHFGFGPHKHKAPYVRSEGRKFERARGRRKSRAFKV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
13	Phosphorylation	ERHHVKKSQRSKPAS CHHCCCHHHCCCCCC	25.71	21712547
16	Phosphorylation	HVKKSQRSKPASENV CCCHHHCCCCCCCHH	35.04	28889911
20	Phosphorylation	SQRSKPASENVYLKL HHCCCCCCCHHHHHH	37.93	28889911
56	Phosphorylation	KRLFQSKTNRPPISI HHHHHCCCCCCCCCH	41.53	24763107
64	Phosphorylation	NRPPISISKIAALTS CCCCCCHHHHHHHHC	15.95	28889911
81	Phosphorylation	SASSQNKTTVVVGTV CCCCCCCCEEEEEEE	32.16	25720772
82	Phosphorylation	ASSQNKTTVVVGTVT CCCCCCCEEEEEEEC	16.95	25720772
87	Phosphorylation	KTTVVVGTVTDDERM CCEEEEEEECCCCCE	14.50	28889911
89	Phosphorylation	TVVVGTVTDDERMLT EEEEEEECCCCCEEC	37.26	28889911
134	Phosphorylation	QLALRAPTGSNTVLV EEEHHCCCCCCEEEE	52.86	28889911
136	Phosphorylation	ALRAPTGSNTVLVRG EHHCCCCCCEEEECC	31.63	28889911
138	Phosphorylation	RAPTGSNTVLVRGKK HCCCCCCEEEECCHH	19.53	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RL18A_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RL18A_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RL18A_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
YGNB_SCHPO	nap2	physical	26771498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RL18A_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-16; SER-64; THR-87;THR-89; THR-134; SER-136 AND THR-138, AND MASS SPECTROMETRY.	18257517 [Abstract]