SPS1_YEAST - dbPTM
SPS1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SPS1_YEAST
UniProt AC P08458
Protein Name Sporulation-specific protein 1
Gene Name SPS1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 490
Subcellular Localization Nucleus . Cytoplasm .
Protein Description Serine/threonine protein kinase required for spore wall development..
Protein Sequence MESKEISIRSRTPPSKLYSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKRKPPKLQGPFSDAAKDFVAGCLVKTPADRPSAYNLLSFEFVKNITITNLKSDVDLIKQKKVQERYTKVPKYPLQNRLYKNSNTVRGKEFWNFESTRLSTTQISKEELSPITQDSPTSSLNMESPYLLHGQTVTPITNPSSSSFRKCTQPVFELDSGMDIDSGCPNAQAETEIVPLSNHNKKHKKNDIQALKIEKFDYLKNIVSHILNRMYDRARDDETRKYVNEMLKQFIKTEANVPGFNEVFIEEISLRIEAIKKGFV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
22PhosphorylationSKLYSIQSCIGRGNF
HHHEEHHHHCCCCCH		13.1626447709
224AcetylationLSKYDPMKVMTNLPK
HHHCCCCHHHHCCCC		33.9525381059
231AcetylationKVMTNLPKRKPPKLQ
HHHHCCCCCCCCCCC		75.9925381059
282PhosphorylationITITNLKSDVDLIKQ
EEEECCCCHHHHHHH		46.1428889911
301AcetylationERYTKVPKYPLQNRL
HHHHCCCCCCCCCCC		63.5925381059
310AcetylationPLQNRLYKNSNTVRG
CCCCCCCCCCCCCCC		59.5025381059
318AcetylationNSNTVRGKEFWNFES
CCCCCCCCEECCCCC		38.8925381059
339PhosphorylationQISKEELSPITQDSP
CCCHHHCCCCCCCCC		19.9628889911
345PhosphorylationLSPITQDSPTSSLNM
CCCCCCCCCCCCCCC		21.9128889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SPS1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SPS1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SPS1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ARP2_YEASTARP2physical
11805837
PP2A2_YEASTPPH22physical
11805837
PP2A1_YEASTPPH21physical
11805837
IDH1_YEASTIDH1physical
11805837
PET10_YEASTPET10physical
11805837
RPN8_YEASTRPN8physical
11805837
ATPG_YEASTATP3physical
11805837
PHO84_YEASTPHO84physical
11805837
YHJ3_YEASTYHR033Wphysical
11805837
PPID_YEASTCPR6physical
11805837
VATD_YEASTVMA8physical
11805837
AHA1_YEASTAHA1physical
11805837
PRTB_YEASTPRB1physical
11805837
SDHB_YEASTSDH2physical
11805837
VPS74_YEASTVPS74physical
11805837
NMD5_YEASTNMD5physical
11805837
TFC3_YEASTTFC3physical
16554755
RV167_YEASTRVS167physical
16554755
PYC1_YEASTPYC1physical
16554755
SPO75_YEASTSPO75physical
16554755
HFI1_YEASTHFI1physical
16554755
DPH1_YEASTDPH1physical
16319894
I23O_YEASTBNA2physical
16319894
SGF73_YEASTSGF73physical
16319894
TMA16_YEASTTMA16physical
16319894
RBD2_YEASTRBD2physical
16319894
STE20_YEASTSTE20genetic
19269370
IME1_YEASTIME1genetic
19269370
CTI6_YEASTCTI6genetic
19269370
PSB2_YEASTPUP1physical
15687504
ARO8_YEASTARO8physical
20489023
APN1_YEASTAPN1physical
21460040
ARF3_YEASTARF3physical
21460040
TCPZ_YEASTCCT6physical
21460040
PRP17_YEASTCDC40physical
21460040
CSK2B_YEASTCKB1physical
21460040
CYC7_YEASTCYC7physical
21460040
DIB1_YEASTDIB1physical
21460040
DOM34_YEASTDOM34physical
21460040
SYDC_YEASTDPS1physical
21460040
SYEC_YEASTGUS1physical
21460040
MPC54_YEASTMPC54physical
21460040
RDS2_YEASTRDS2physical
21460040
RNA1_YEASTRNA1physical
21460040
SDS22_YEASTSDS22physical
21460040
HSP7F_YEASTSSE1physical
21460040
UBC6_YEASTUBC6physical
21460040
UBP10_YEASTUBP10physical
21460040
PLPHP_YEASTYBL036Cphysical
21460040
YKC3_YEASTYKL023Wphysical
21460040
YM54_YEASTYMR196Wphysical
21460040
SIR2_YEASTSIR2genetic
21902802
BCH2_YEASTBCH2genetic
22282571
ATG1_YEASTATG1genetic
22282571
KNH1_YEASTKNH1genetic
22282571
CYK3_YEASTCYK3genetic
22282571
COQ1_YEASTCOQ1genetic
22282571
YO289_YEASTYOR289Wgenetic
22282571
PHR_YEASTPHR1genetic
22282571
YP109_YEASTYPL109Cgenetic
22282571
RS10A_YEASTRPS10Agenetic
22282571
SST2_YEASTSST2genetic
22282571
LCF1_YEASTFAA1genetic
22282571
NEW1_YEASTNEW1genetic
22282571
RRP8_YEASTRRP8genetic
22282571
STB5_YEASTSTB5genetic
22282571
ADE_YEASTAAH1genetic
22282571
GGPPS_YEASTBTS1genetic
22282571
HMO1_YEASTHMO1genetic
22282571
MET22_YEASTMET22genetic
22282571
RL22A_YEASTRPL22Agenetic
22282571
BMH1_YEASTBMH1physical
25409301
BMH2_YEASTBMH2physical
25409301
GPR1_YEASTGPR1genetic
27708008
CDC15_YEASTCDC15genetic
27708008
RPB1_YEASTRPO21genetic
27708008
TIM22_YEASTTIM22genetic
27708008
TAF12_YEASTTAF12genetic
27708008
TCPZ_YEASTCCT6genetic
27708008
MOB2_YEASTMOB2genetic
27708008
PRS8_YEASTRPT6genetic
27708008
TEL2_YEASTTEL2genetic
27708008
DAM1_YEASTDAM1genetic
27708008
CDC23_YEASTCDC23genetic
27708008
LIP1_YEASTLIP1genetic
27708008
SMC5_YEASTSMC5genetic
27708008
BUR1_YEASTSGV1genetic
27708008
RRP8_YEASTRRP8genetic
27708008
STB5_YEASTSTB5genetic
27708008
SST2_YEASTSST2genetic
27708008
ADE_YEASTAAH1genetic
27708008
RS10A_YEASTRPS10Agenetic
27708008
LCF1_YEASTFAA1genetic
27708008
GGPPS_YEASTBTS1genetic
27708008
SPO77_YEASTSPO77genetic
27182947
STP2_YEASTSTP2genetic
27182947
AMA1_YEASTAMA1genetic
27182947
SSP1_YEASTSSP1physical
27182947
THG1_HUMANTHG1Lphysical
27107014
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SPS1_YEAST

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Related Literatures of Post-Translational Modification

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