UniProt ID | IKS1_YEAST | |
---|---|---|
UniProt AC | P47042 | |
Protein Name | Probable serine/threonine-protein kinase IKS1 | |
Gene Name | IKS1 | |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
Sequence Length | 667 | |
Subcellular Localization | ||
Protein Description | ||
Protein Sequence | MSLVPYEEGSLILDDPNSKSVVVVNPTSGTLSFFQQDNSNNDSELNEDQTASLSALDFPSGIHQYKSPIASYVCPQCGTEINPDIINRRQLHRRASAGVESESSRLSIPENTVPLGFEFANSSFSRRYFQSLERNHRHYALQNDSNNKQGQFSKNKYFIPDDLFIPGYFRKFFKILSLLGNGARGSVYKVVHTIGNTELGVFALKKIPIGNDMEWFNKCIREVKALSSLTHKSANLITYNHVWLEMDSSVGFVRSIDGSQSDSQEEVPCIFILQQYCSGGNLEDCILRKVFNRFSDTESPEERKKKFRTRKKNHGKSGEVGLSTEQLVSIIRDIARGLHELHSIGLIHRDLKPSNCLLLTPFKSDNENDNVYDREHNSDEFFPSIVIGDLGESQLEGESRLGTGCTGTLEFTAPDLIIQGRPVSSSTLPSRSSHTYNEYTFASDMYSLGMICYFIVFGELPFEPQLDIVDLKVRIKNFRFDTEGMIEKHQAMKLKPIDRRIFHLMDALLQPNNDARPTAKTVEETLDEMLINSKPGKKFWKENVDSTLNFSTISEVNENTNSFTDDYIDGDNVTLSLPAPEENLSTVSTQNLQKYSALNRTIQVCYKLVSMILTIIIFKCTKTGSWLSYMSLILLGMVFKSPADERGKHARALVLLAFIAACKKYIY | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
2 | Phosphorylation | ------MSLVPYEEG ------CCCCCCCCC | 37.77 | 30377154 | |
10 | Phosphorylation | LVPYEEGSLILDDPN CCCCCCCCEEECCCC | 18.60 | 30377154 | |
96 | Phosphorylation | RQLHRRASAGVESES HHHHHHHHCCCCCCC | 24.60 | 25533186 | |
101 | Phosphorylation | RASAGVESESSRLSI HHHCCCCCCCCCCCC | 40.13 | 22890988 | |
123 | Phosphorylation | GFEFANSSFSRRYFQ CCEECCCHHHHHHHH | 27.35 | 30377154 | |
125 | Phosphorylation | EFANSSFSRRYFQSL EECCCHHHHHHHHHH | 20.14 | 30377154 | |
295 | Phosphorylation | RKVFNRFSDTESPEE HHHHHHCCCCCCHHH | 40.15 | 29136822 | |
297 | Phosphorylation | VFNRFSDTESPEERK HHHHCCCCCCHHHHH | 36.84 | 27717283 | |
299 | Phosphorylation | NRFSDTESPEERKKK HHCCCCCCHHHHHHH | 39.44 | 21440633 | |
403 | Phosphorylation | EGESRLGTGCTGTLE CCCCCCCCCCCCEEE | 33.40 | 23607784 | |
406 | Phosphorylation | SRLGTGCTGTLEFTA CCCCCCCCCEEEEEC | 34.25 | 25752575 | |
408 | Phosphorylation | LGTGCTGTLEFTAPD CCCCCCCEEEEECCC | 12.64 | 30377154 | |
424 | Phosphorylation | IIQGRPVSSSTLPSR EEECEECCCCCCCCC | 22.66 | 30377154 | |
425 | Phosphorylation | IQGRPVSSSTLPSRS EECEECCCCCCCCCC | 27.81 | 30377154 | |
525 | Phosphorylation | TAKTVEETLDEMLIN CCHHHHHHHHHHHHC | 26.46 | 27017623 | |
533 | Phosphorylation | LDEMLINSKPGKKFW HHHHHHCCCCCCCHH | 32.98 | 27017623 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of IKS1_YEAST !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of IKS1_YEAST !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of IKS1_YEAST !! |
Kegg Drug | ||||||
---|---|---|---|---|---|---|
DrugBank | ||||||
There are no disease associations of PTM sites. |
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Phosphorylation | |
Reference | PubMed |
"A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-96; THR-403 AND THR-406,AND MASS SPECTROMETRY. | |
"Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases."; Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.; Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-96, AND MASSSPECTROMETRY. |